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Tbx18 gene directs conversion of cardiomyocytes to genuine pacemaker cells

Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene (Tbx18)-a major step forward in the decade-long search for a biological therapy to correct erratic and failing heartbeats.

18 Dec 2012

Maryland researchers launch groundbreaking study into spread of drug-resistant malaria in Burma

University of Maryland School of Medicine researchers have launched groundbreaking research into the spread of potentially deadly drug-resistant malaria in the developing Southeast Asian nation of Myanmar, also known as Burma.

17 Dec 2012

‘Ambu-lysis’ edges closer for stroke patients

A pilot trial of giving suitable stroke patients intravenous thrombolysis before their arrival in hospital has produced promising results.

17 Dec 2012

NeoGenomics launches FISH assay for surveillance of patients with Barrett's Esophagus

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today it has validated and launched a laboratory developed Fluorescent in Situ Hybridization assay for the surveillance of patients with Barrett's Esophagus.

17 Dec 2012

Study reveals how BRCA1 enzymatic activity may stop cancer cell growth

A new study by Georgetown University Medical Center researchers reveals how a well-known tumor suppressor gene may be functioning to stop cancer cell growth.

17 Dec 2012

Dyslipidaemia: an interview with Prof. Peter Kokkinos

Dyslipidemia is defined as abnormal levels of blood lipids (fats) and cholesterol. The most common dyslipidaemias are high blood cholesterol (Total Cholesterol) and triglyceride levels, high levels of low-density lipoprotein (LDL) cholesterol (‘bad’ cholesterol) and low levels of high-density lipoprotein (HDL) cholesterol (‘good’ cholesterol).

17 Dec 2012

New technique could help develop more-specific, cell-based immune therapies for cancer

A team led by Michel Sadelain, MD, PhD, Director of the Center for Cell Engineering at Memorial Sloan-Kettering Cancer Center, has shown for the first time the effectiveness of a new technique that could allow the development of more-specific, cell-based immune therapies for cancer.

17 Dec 2012

Blocking single tiny blood vessel in the brain can harm neural tissue and even alter behavior

Blocking a single tiny blood vessel in the brain can harm neural tissue and even alter behavior, a new study from the University of California, San Diego has shown. But these consequences can be mitigated by a drug already in use, suggesting treatment that could slow the progress of dementia associated with cumulative damage to miniscule blood vessels that feed brain cells.

17 Dec 2012

Aspen Dental announces opening of new dental office in Waltham, MA

Aspen Dental is proud to announce that a new Aspen Dental office is opening in Waltham, MA on Thursday, Dec. 20. Located at 1030 Main St, Unit J, the practice will provide dental services that range from dentures and preventive care to general dentistry and restoration.

15 Dec 2012

IRCM study identifies mechanism responsible for generation of fingers and toes

Dr. Marie Kmita and her research team at the IRCM contributed to a multidisciplinary research project that identified the mechanism responsible for generating our fingers and toes, and revealed the importance of gene regulation in the transition of fins to limbs during evolution.

15 Dec 2012

Banner MD Anderson Cancer Center to expand its outpatient cancer facility

Banner MD Anderson Cancer Center on the Banner Gateway campus will break ground in January 2013 on an expansion of its outpatient cancer facility, offering a new service and additional equipment and treatment areas to meet the needs of its rapidly growing patient population.

15 Dec 2012

New Aspen Dental office to open in Auburn, ME

Aspen Dental is proud to announce that a new Aspen Dental office is opening in Auburn, ME on Thursday, Dec. 20. Located near Wal-Mart at 791 Turner Street, the practice will provide dental services that range from dentures and preventive care to general dentistry and restoration.

15 Dec 2012

Research provides broader understanding of processes that lead to Alzheimer's disease

Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aβ) protein causes neuronal loss in patients.

15 Dec 2012

Scientists discover new gene mechanism that appears to regulate triglyceride levels

Scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University have discovered a new gene mechanism that appears to regulate triglyceride levels.

15 Dec 2012

Fluidigm, GIS announce establishment of first single-cell genomics research center in Asia

The Genome Institute of Singapore (GIS), an institute under the umbrella of the Agency for Science, Technology and Research, and Fluidigm Corporation today announced the establishment of the first research center in Asia exclusively dedicated to accelerating the understanding of how individual cells work, and how diagnosis and treatment might be enhanced through insight derived from single cells.

15 Dec 2012

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments for diseases associated with protein misfolding and apoptosis, today announced that it has licensed the LymPro Alzheimer's Disease Diagnostic Blood Test (LymPro) from Memory Dx, LLC (MDx), formerly known as Provista Life Sciences, Inc.

14 Dec 2012

Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

A Cedars-Sinai physician-scientist has been awarded a $3 million grant from the California Institute for Regenerative Medicine to study with new stem cell technology Charcot-Marie-Tooth disease, the most common inherited neurological disorder and which damages nerves that control muscles.

14 Dec 2012

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

The plague-causing bacteria Yersinia pestis evades detection and establishes a stronghold without setting off the body's early alarms.

14 Dec 2012

High-dose vitamin D can reduce risk of respiratory tract infections

Treating infection-prone patients over a 12-month period with high doses of vitamin D reduces their risk of developing respiratory tract infection - and consequently their antibiotic requirement. This according to a new study by researchers at Karolinska Institutet and Karolinska University Hospital published in the online scientific journal BMJ Open.

14 Dec 2012

Researchers question animal models that measure generalized anxiety disorder

Pre-clinical trials - the stage at which medications or therapies are tested on animals like laboratory mice - is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before a drug is administered to patients.

14 Dec 2012

Laboratory News and Research

Tbx18 gene directs conversion of cardiomyocytes to genuine pacemaker cells

Maryland researchers launch groundbreaking study into spread of drug-resistant malaria in Burma

‘Ambu-lysis’ edges closer for stroke patients

NeoGenomics launches FISH assay for surveillance of patients with Barrett's Esophagus

Study reveals how BRCA1 enzymatic activity may stop cancer cell growth

Dyslipidaemia: an interview with Prof. Peter Kokkinos

New technique could help develop more-specific, cell-based immune therapies for cancer

Blocking single tiny blood vessel in the brain can harm neural tissue and even alter behavior

Aspen Dental announces opening of new dental office in Waltham, MA

IRCM study identifies mechanism responsible for generation of fingers and toes

Banner MD Anderson Cancer Center to expand its outpatient cancer facility

New Aspen Dental office to open in Auburn, ME

Research provides broader understanding of processes that lead to Alzheimer's disease

Scientists discover new gene mechanism that appears to regulate triglyceride levels

Fluidigm, GIS announce establishment of first single-cell genomics research center in Asia

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

High-dose vitamin D can reduce risk of respiratory tract infections

Researchers question animal models that measure generalized anxiety disorder

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