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Lung cancer is the world's most common cancer and kills more people than any other cancer. In 2008, approximately 1.52 million new cases of lung cancer were diagnosed worldwide, with 1.31 million people dying from the disease.(14) In the United States, an estimated 161,840 deaths, accounting for 29 percent of all cancer deaths, occurred in 2008, according to the American Cancer Society (ACS).
Anxiety regarding inconclusive cancer screening test results is far less than claimed

Anxiety regarding inconclusive cancer screening test results is far less than claimed

Anxiety regarding inconclusive cancer screening test results among some patients is real and is only natural. [More]
Experts at ABTA conference reveal possible causes, risk factors for brain tumors

Experts at ABTA conference reveal possible causes, risk factors for brain tumors

Today, nearly 700,000 people in the U.S. are living with a brain tumor, and yet, when it comes to pinpointing causes or risk factors, scientists are still searching for answers. [More]
CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Over half of patients being seen in the clinic for a diagnosed brain tumor have metastatic cancer, which has no treatment and detrimental outcomes in most cases. [More]
Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS). [More]
Prognostic value of visceral plural invasion limited in part-solid lung cancer

Prognostic value of visceral plural invasion limited in part-solid lung cancer

Visceral plural invasion is a significant predictor of survival in patients with small solid lung tumours but not in patients with part-solid tumours, Japanese study findings indicate. [More]
Combined risk score enhances radiation pneumonitis prediction

Combined risk score enhances radiation pneumonitis prediction

Combining dose-volume histogram parameters with age and baseline pulmonary fibrosis score creates a novel predictive risk score that improves prediction of radiation pneumonitis in patients receiving concurrent chemoradiotherapy for non-small-cell lung cancer, research shows. [More]
Standard TFI definition still applies for relapsed SCLC classification

Standard TFI definition still applies for relapsed SCLC classification

Italian researchers have confirmed that using a treatment-free interval cut-off of 60 days to classify relapsed small-cell lung cancer as sensitive or resistant can be regarded as the standard definition. [More]
Co-targeting strategies suggested for EGFR-TKI resistance in NSCLC

Co-targeting strategies suggested for EGFR-TKI resistance in NSCLC

Researchers have identified additional resistance mechanisms that could be targeted to improve the efficacy of irreversible epidermal growth factor receptor-tyrosine kinase inhibitors in patients with non-small-cell lung cancer harbouring both EGFR and T790M mutations. [More]
CRIPTO1 role in TKI resistance elucidated

CRIPTO1 role in TKI resistance elucidated

Overexpression of CRIPTO1 may explain intrinsic tyrosine kinase inhibitor resistance in around 10% of patients with non-small-cell lung cancer and endothelial growth factor receptor mutations, research indicates. [More]
Collaboration classification useful for Japanese lung cancer patients

Collaboration classification useful for Japanese lung cancer patients

Epidermal growth factor receptor status and prognosis in Japanese patients can be predicted by a recently developed lung adenocarcinoma classification system, say researchers. [More]
Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer. [More]
ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

ROS1 fusion genes were successfully detected independent of gender or smoking history in young East Asian patients with lung adenocarcinoma, a histological subgroup in non-small cell lung cancer (NSCLC), using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC) diagnostic tests. [More]
Study confirms effectiveness of EKF PointMan technology for isolating low-level DNA mutations in blood

Study confirms effectiveness of EKF PointMan technology for isolating low-level DNA mutations in blood

EKF Diagnostics, the global diagnostics company, announces that the latest results from its collaboration with the Institute of Life Sciences at the University of Swansea, UK, have continued to confirm the effectiveness of its PointMan DNA enrichment technology for isolating and characterizing low-level DNA mutations in blood. [More]
First Edition: July, 21, 2014

First Edition: July, 21, 2014

Today's headlines include a story about an effort by regulators to widen insurer networks, as well as a range of other health policy developments. [More]

New material can extract atoms of rare or dangerous elements from air

Scientists at the University of Liverpool have successfully tested a material that can extract atoms of rare or dangerous elements such as radon from the air. [More]
Salk scientists identify gene that fights metastasis of common lung cancer

Salk scientists identify gene that fights metastasis of common lung cancer

Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers. [More]
TAZ represents a novel therapeutic target in NSCLC

TAZ represents a novel therapeutic target in NSCLC

Patients with non-small-cell lung cancer who express high levels of transcriptional coactivator with PDZ-binding motif may be a clinically distinct subgroup with an unfavourable prognosis, researchers report. [More]
CIP2A pathway involved in erlotinib response

CIP2A pathway involved in erlotinib response

Researchers have identified a novel mechanism, involving the cancerous inhibitor of protein phosphatase 2A pathway, which mediates the anti-tumour effects of erlotinib in non-small-cell lung cancer cells without epidermal growth factor receptor mutations. [More]
New role for cholesterol in activation of cellular signaling pathway that linked to cancer

New role for cholesterol in activation of cellular signaling pathway that linked to cancer

Everyone knows that cholesterol, at least the bad kind, can cause heart disease and hardening of the arteries. Now, researchers at the University of Illinois at Chicago describe a new role for cholesterol in the activation of a cellular signaling pathway that has been linked to cancer. [More]
Yashoda Cancer Institute uses Varian Clinac medical linear accelerator for radiotherapy treatments

Yashoda Cancer Institute uses Varian Clinac medical linear accelerator for radiotherapy treatments

Clinicians at a leading cancer center in India have become the first in the country to commence advanced lung, liver and brain radiotherapy treatments using an upgraded Clinac medical linear accelerator from Varian Medical Systems. [More]