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Lung cancer is the world's most common cancer and kills more people than any other cancer. In 2008, approximately 1.52 million new cases of lung cancer were diagnosed worldwide, with 1.31 million people dying from the disease.(14) In the United States, an estimated 161,840 deaths, accounting for 29 percent of all cancer deaths, occurred in 2008, according to the American Cancer Society (ACS).
Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Researchers from the Genes and Cancer research group at the Bellvitge Biomedical Research Institute have identified inactivating mutations in a number of genes that code for HLA-I histocompatibility complex proteins, which are involved in the immune response and can condition the tesponse of lung cancer patients to immunotherapy. [More]
Epigenetic changes drive successful metastases of pancreatic cancer cells

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. [More]
LUNGevity Foundation launches new mobile app to help lung cancer patients manage life

LUNGevity Foundation launches new mobile app to help lung cancer patients manage life

LUNGevity, the nation’s leading lung cancer-focused nonprofit organization today launched a new mobile application designed to make understanding and living with lung cancer less daunting and considerably more manageable. [More]
NTNU researchers testing use of new removable stent in the lungs

NTNU researchers testing use of new removable stent in the lungs

A knitted rag sock inspired this professor and MD to develop a stent that can easily be removed after it has done its job. [More]
Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use. [More]
MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer [More]
NCCN publishes new easy-to-understand patient education resources focused on brain cancer

NCCN publishes new easy-to-understand patient education resources focused on brain cancer

The National Comprehensive Cancer Network has published the NCCN Guidelines for Patients and NCCN Quick Guide sheets for Brain Cancer - Gliomas—the first in a series of patient education resources focused on Brain Cancer. [More]
Place of residence contributes to late-stage diagnosis of colorectal cancer, study finds

Place of residence contributes to late-stage diagnosis of colorectal cancer, study finds

In addition to a person's race or ethnicity, where they live can matter in terms of whether they are diagnosed at a late stage for colorectal cancer, according to a recent study led by a researcher at the School of Public Health at Georgia State University. [More]
UI scientists reveal how high-dose vitamin C damages cancer cells

UI scientists reveal how high-dose vitamin C damages cancer cells

Vitamin C has a patchy history as a cancer therapy, but researchers at the University of Iowa believe that is because it has often been used in a way that guarantees failure. [More]
Yale study highlights treatment burden experienced by older lung cancer patients

Yale study highlights treatment burden experienced by older lung cancer patients

Depending on the type of treatment older lung cancer patients receive, they can spend an average of one in three days interacting with the healthcare system in the first 60 days after surgery or radiation therapy, according to a study by Yale researchers. [More]
Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells. [More]
Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

Delayed chemotherapy after surgery may benefit lung cancer patients, new Yale study suggests

A new Yale study suggests that patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to the researchers. [More]
NSCLC patients treated with surgery may benefit from delayed chemotherapy, study shows

NSCLC patients treated with surgery may benefit from delayed chemotherapy, study shows

A new study suggests patients who recover slowly from non-small-cell lung cancer (NSCLC) surgery may still benefit from delayed chemotherapy started up to four months after surgery, according to a new study published online by JAMA Oncology. [More]
Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

According to a new comprehensive financial analysis reported in the Journal of the American Medical Association and The Washington Post diabetes leads a list of just 20 diseases and conditions that account for more than half of all spending on healthcare in the United States. [More]
A new strategy to fight prostate cancer

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Hospitals eliminate bedsore occurrence using early detection technology

Hospitals eliminate bedsore occurrence using early detection technology

Using technology adapted from NASA's Mars lander as part of a large-scale bedsore reduction program, over half of the 13 participating hospitals were able to eliminate the occurrence of new bedsores completely; an additional 3 hospitals achieved reductions ranging from 11% to 90%. [More]
Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

Study reveals impact of histology on SBRT treatment in early-stage NSCLC patients

Early-stage non-small cell lung cancer (NSCLC) patients with squamous cell carcinoma (SqCC) have a significantly higher rate of local failure after stereotactic body radiation therapy (SBRT) than other NSCLC histological subtypes. [More]
New computational tool can predict personal cancer driver genes to optimize treatment

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments. [More]
Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own. [More]
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