Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Cardiologist reveals 13 facts about heart disease in women

Cardiologist reveals 13 facts about heart disease in women

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Salk Institute researchers reveal how to curb immune enthusiasm

Salk Institute researchers reveal how to curb immune enthusiasm

Dermatologist reveals how smoking can affect the skin

Dermatologist reveals how smoking can affect the skin

AARDA recognizes AARDA founder and longtime staff as its latest Autoimmune Heroes

AARDA recognizes AARDA founder and longtime staff as its latest Autoimmune Heroes

Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

Researchers explore kidney biomarkers to track lupus progression

Researchers explore kidney biomarkers to track lupus progression

Researchers show how microRNAs play key role in tumor progression and response to radiation

Researchers show how microRNAs play key role in tumor progression and response to radiation

Results of high-impact clinical trials could improve kidney-related medical care

Results of high-impact clinical trials could improve kidney-related medical care

Bilingual support group addressing health needs of lupus patients has positive impact, study finds

Bilingual support group addressing health needs of lupus patients has positive impact, study finds

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research shows how immune system avoids attacking own tissues with antibodies

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

New research identifies mechanism that may lead to treatment of fibrosis in scleroderma

New research identifies mechanism that may lead to treatment of fibrosis in scleroderma

Two leading non-profit organizations sign strategic affiliation to hasten drug development

Two leading non-profit organizations sign strategic affiliation to hasten drug development

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models