Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Women have statistically lower incidence of severe psoriasis compared to men, study reveals

Women have statistically lower incidence of severe psoriasis compared to men, study reveals

Linking RNA to autoimmune diseases

Linking RNA to autoimmune diseases

Study identifies therapeutic target for diabetic retinopathy

Study identifies therapeutic target for diabetic retinopathy

New biomarkers may help in diagnosis and management of Crohn's disease

New biomarkers may help in diagnosis and management of Crohn's disease

New drug-like compound shows potential to treat symptoms of lupus

New drug-like compound shows potential to treat symptoms of lupus

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

Newly-identified autoimmune endocrine disease is caused by thymomas, study finds

SBP researchers identify new regulator of innate immune response to foreign invaders

SBP researchers identify new regulator of innate immune response to foreign invaders

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Penn-led researchers gain better understanding of how T cells support long-lived plasma cells

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Genetic variant encoded in NCF1 linked to increased risk for autoimmune diseases, study shows

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Common drug for autoimmune disease may increase risk of myeloid neoplasms

Cardiologist reveals 13 facts about heart disease in women

Cardiologist reveals 13 facts about heart disease in women

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Salk Institute researchers reveal how to curb immune enthusiasm

Salk Institute researchers reveal how to curb immune enthusiasm

Dermatologist reveals how smoking can affect the skin

Dermatologist reveals how smoking can affect the skin

AARDA recognizes AARDA founder and longtime staff as its latest Autoimmune Heroes

AARDA recognizes AARDA founder and longtime staff as its latest Autoimmune Heroes

Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

U-M researchers identify gene expression linked to gender differences in autoimmune diseases