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EMD Serono begins MSB0010718C Phase II study in mMCC patients

EMD Serono begins MSB0010718C Phase II study in mMCC patients

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, today announced the initiation of an international Phase II study designed to assess the efficacy and safety of MSB0010718C, an investigational fully human IgG1 monoclonal antibody that binds to programmed death-ligand 1 (PD-L1). [More]
Endoscopic resection not always best for localized, early-stage esophageal cancer: Study

Endoscopic resection not always best for localized, early-stage esophageal cancer: Study

A new study, published in the July, 2014, issue of the Journal of the National Cancer Institute by Northwestern Medicine- researchers, sheds new light on the risks associated with the growing popularity of endoscopic resection in the treatment of localized, early-stage esophageal cancer. [More]
PLXNA4 gene may increase risk of developing Alzheimer's disease

PLXNA4 gene may increase risk of developing Alzheimer's disease

Researchers from Boston University School of Medicine report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically. [More]
Adopting a comprehensive and integrative healing strategy for cancer

Adopting a comprehensive and integrative healing strategy for cancer

The cancer drugs, radiation therapy and cancer surgery available today help millions of people survive their cancer. [More]
Mercy achieves national ranking for specialty care, earns No. 2 rank in Maryland

Mercy achieves national ranking for specialty care, earns No. 2 rank in Maryland

Mercy Medical Center has been ranked nationally in three adult medical specialties (Gynecology, Orthopedics, and Neurology/Neurosurgery), named a high performer in six key adult specialties, and further recognized as the #2 hospital in the State of Maryland for 2014-15 by U.S. News & World Report. [More]
Pediatrician currently utilizes Quotient ADHD test on patients

Pediatrician currently utilizes Quotient ADHD test on patients

Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood condition characterized by more than normal difficulty with focus, behavior control, impulsivity and hyperactivity. [More]
Early life experiences influence risk of cognitive impairment in later life

Early life experiences influence risk of cognitive impairment in later life

Early life experiences, such as childhood socioeconomic status and literacy, may have greater influence on the risk of cognitive impairment late in life than such demographic characteristics as race and ethnicity, a large study by researchers with the UC Davis Alzheimer's Disease Center and the University of Victoria, Canada, has found. [More]
Study: Slow walking, memory complaints may predict future dementia

Study: Slow walking, memory complaints may predict future dementia

A study involving nearly 27,000 older adults on five continents found that nearly 1 in 10 met criteria for pre-dementia based on a simple test that measures how fast people walk and whether they have cognitive complaints. [More]
Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS). [More]
Protective effects of ischemic preconditioning on focal cerebral infarction linked with upregulation of VEGF

Protective effects of ischemic preconditioning on focal cerebral infarction linked with upregulation of VEGF

Neuroprotection by ischemic preconditioning has been confirmed by many studies, but the precise mechanism remains unclear. [More]
Highlights: Calif. nurse union in contract fight; personhood measure in Colo.; Md. transgender coverage

Highlights: Calif. nurse union in contract fight; personhood measure in Colo.; Md. transgender coverage

But this is no church service, and nurses are not here to worship. The California Nurses Association is rousing its troops for battle. California's powerful nurses' union will begin bargaining next week with Kaiser Permanente on a new four-year contract for nurses at its Northern California hospitals. (Kaiser Health News is not affiliated with Kaiser Permanente.) Kaiser operates the largest hospital system in the state, by number of hospitals and number of hospital beds, and is the eighth largest health system in the country (Dembosky, 7/22). [More]
Monitoring pulse regularly after stroke helps prevent next stroke

Monitoring pulse regularly after stroke helps prevent next stroke

New research suggests that regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke may be a simple and effective first step in detecting irregular heartbeat, a major cause of having a second stroke. [More]
Autoimmune diseases share certain pathogenic mechanisms with cancer

Autoimmune diseases share certain pathogenic mechanisms with cancer

Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report by George Washington University researcher Linda Kusner, Ph.D., published in PLOS ONE on July 22. [More]
Tiny gold particles can make cell membranes deliver drugs directly to target cells

Tiny gold particles can make cell membranes deliver drugs directly to target cells

A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells. [More]
Signs and symptoms of Lewy body dementia

Signs and symptoms of Lewy body dementia

"I watched my husband experience a decline in cognition followed by a period of what seemed like improved function only to plunge again into confusion with more frequent hallucinations," says one caregiver newly acquainted with Lewy body dementia (LBD). [More]
Researchers collaborate to tackle rare diseases

Researchers collaborate to tackle rare diseases

Support from a network of leading researchers across Europe specialised in a rare auto-immune disease with unmet medical needs could help test several novel treatments [More]
First diagnostic criteria proposed for Christianson Syndrome

First diagnostic criteria proposed for Christianson Syndrome

Because the severe autism-like condition Christianson Syndrome was only first reported in 1999 and some symptoms take more than a decade to appear, families and doctors urgently need fundamental information about it. A new study that doubles the number of cases now documented in the scientific literature provides the most definitive characterization of CS to date. [More]
Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers identify group of cells in brain that plays important role in Down syndrome

Researchers from UC Davis School of Medicine and Shriners Hospitals for Children - Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome. [More]
Correlation between sensitivity to light or noise and increased emotional symptoms in concussed teens

Correlation between sensitivity to light or noise and increased emotional symptoms in concussed teens

Two researchers from the University of Kentucky have demonstrated a connection between sensitivity to light or noise and increased emotional symptoms in teens who have suffered a concussion. [More]
Researchers receive $2.098 million grant to study recovery of language after stroke

Researchers receive $2.098 million grant to study recovery of language after stroke

An interdisciplinary group of researchers at the University of Arizona has been awarded a $2 million grant from the National Institutes of Health to study language abilities in patients recovering from a stroke. [More]