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Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

What started as an experiment to probe brain circuits involved in compulsive behavior has revealed a surprising connection with obesity. [More]

Stroke experts discuss benefits of endovascular therapy in treating acute ischemic stroke

Covidien, a leading global provider of healthcare products, recently brought together six of the world's prominent thought-leaders in stroke at the 2013 European Stroke Conference. [More]
Children's Hospitals and Clinics of Minnesota honored as 2013-2014 Best Children's Hospital

Children's Hospitals and Clinics of Minnesota honored as 2013-2014 Best Children's Hospital

Children's Hospitals and Clinics of Minnesota has been honored by U.S. News & World Report as a 2013-2014 Best Children's Hospital. Children's has been ranked on the list every year since the program's inception in 2007. [More]
Report shows low baseline DBP associated with brain atrophy in patients with arterial disease

Report shows low baseline DBP associated with brain atrophy in patients with arterial disease

Low baseline diastolic blood pressure appears to be associated with brain atrophy in patients with arterial disease, whenever declining levels of blood pressure over time among patients who had a higher baseline BP were associated with less progression of atrophy, according to a report published Online First by JAMA Neurology, a JAMA Network publication. [More]
SUNY Downstate to receive grant to advance blood test to predict breast cancer progression

SUNY Downstate to receive grant to advance blood test to predict breast cancer progression

SUNY Downstate Medical Center will receive up to $50,000 from the statewide SUNY Technology Accelerator Fund to advance a blood test to determine breast cancer prognosis. [More]
Scientists discover how Arc protein helps translate learning into memory

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted. [More]

Study: Baseball players experience disrupted sleep patterns and fatigue during major league seasons

Strike zone judgment grows worse over the course of a Major League Baseball season in a predictable way, possibly due to the effect of grueling travel schedules, disrupted sleep patterns and fatigue, a Vanderbilt University Medical Center sleep researcher reports at a national meeting this week. [More]

New minimally invasive surgery for epilepsy offers quicker recuperation time for patients

A new minimally invasive laser-based tool for epilepsy surgery offers a quicker recuperation time for patients than major surgery, Mayo Clinic researchers report. The research is ongoing, but preliminary results were recently presented at the American Academy of Neurology. [More]
People with irregular heartbeat may be more likely to develop problems with memory, thinking

People with irregular heartbeat may be more likely to develop problems with memory, thinking

People who develop a type of irregular heartbeat common in old age called atrial fibrillation may also be more likely to develop problems with memory and thinking, according to new research published in the June 5, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. [More]
Atrial fibrillation associated with faster cognitive decline, new research finds

Atrial fibrillation associated with faster cognitive decline, new research finds

An abnormal heartbeat, known as atrial fibrillation, is associated with faster cognitive decline, according to new research from a University of Alabama at Birmingham School of Public Health scientist. [More]
New research suggests that surgical anesthesia may also have lasting effects on adult brains

New research suggests that surgical anesthesia may also have lasting effects on adult brains

As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains. [More]
Study: New genetic marker predicts warfarin dose in African-Americans

Study: New genetic marker predicts warfarin dose in African-Americans

A newfound genetic marker promises to better predict warfarin dose in African-Americans, according to a study published online today in The Lancet. If confirmed in further studies, the finding may help to avert more of the bleeds and blood clots that come when a patient's starting dose misses the drug's narrow safety window. [More]
Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

The same mechanism that lets the immune system mount a massive attack against invading bacteria contributes to the destruction of brain cells as part of Parkinson's disease, according to a study published online today in the Journal of Neuroscience. [More]
UCLA researchers identify abnormal brain networks in Fragile X syndrome

UCLA researchers identify abnormal brain networks in Fragile X syndrome

The genetic malady known as Fragile X syndrome is the most common cause of inherited autism and intellectual disability. Brain scientists know the gene defect that causes the syndrome and understand the damage it does in misshaping the brain's synapses - the connections between neurons. But how this abnormal shaping of synapses translates into abnormal behavior is unclear. [More]

Canadian researcher develops first animal model to study function of C9ORF72 in ALS

Canadian researcher Edor Kabashi of the Université de Montréal has developed the first animal model to study the function of a gene responsible for the highest percentage of ALS, commonly known as Lou Gehrig's disease. Results to date shed light on the cause of the devastating disease. [More]
Naurex initiates Phase I trial of NRX-1074 in normal volunteers

Naurex initiates Phase I trial of NRX-1074 in normal volunteers

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced that it has begun patient dosing in a Phase I trial of its novel, orally active agent NRX-1074. [More]
Researchers establish link between abnormal structure of synapses and behavioral abnormalities of brain circuits in FXS

Researchers establish link between abnormal structure of synapses and behavioral abnormalities of brain circuits in FXS

Fragile X syndrome (FXS) is a genetic malady that is the most common inherited cause of autism and intellectual disability. Brain scientists know the gene defect that causes FXS, and the damage it does-- misshaping the brain's synapses, the connections between neurons. But how that abnormal shaping of synapses translates to abnormal behavior is unclear. [More]
People with narcolepsy have increased number of neurons that produce histamine

People with narcolepsy have increased number of neurons that produce histamine

A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target for this potentially disabling sleep disorder. [More]
Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells appear to promote healing in mice infected with MS-like disease

Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails. [More]
International researchers find how brain cancer cells survive and drive tumor growth

International researchers find how brain cancer cells survive and drive tumor growth

An international team of researchers - led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine - has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism. [More]