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Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.
MGH study reveals effects of obesity on pancreatic and breast cancer

MGH study reveals effects of obesity on pancreatic and breast cancer

Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of obesity to promote cancer progression. In their report published online in the journal Clinical Cancer Research, the research team describes finding an association between obesity and an overabundance of a factor called PlGF (placental growth factor) and that PlGF's binding to its receptor VEGFR-1, which is expressed on immune cells within tumors, promotes tumor progression. [More]
Transition from milk-based diet to family food impacts Infants’ gut bacteria

Transition from milk-based diet to family food impacts Infants’ gut bacteria

It is the transition to eating the family's food and not the weight of the mother that has the greatest impact on the composition of gut bacteria in nine-month-old children. [More]
New research findings uncover lifestyle secrets of ‘mindlessly slim’

New research findings uncover lifestyle secrets of ‘mindlessly slim’

You know that one friend that never worries about weight and seems to stay effortlessly slim? That friend, and others like them might unknowingly possess secrets to helping those who struggle with their weight. [More]
Animal study shows link between oxygen-sensing neurons and fat-burning circuit

Animal study shows link between oxygen-sensing neurons and fat-burning circuit

A new study in animal models, led by scientists at The Scripps Research Institute (TSRI), is the first to show that oxygen sensing in the brain has a role in metabolism and sensing an organism's internal state. [More]
Interplay between gene variant and socio-economic environment may determine girls' food choices

Interplay between gene variant and socio-economic environment may determine girls' food choices

If you're fat, can you blame it on your genes? The answer is a qualified yes. Maybe. Under certain circumstances. Researchers are moving towards a better understanding of some of the roots of obesity. [More]
Transition to family foods drives development of infant gut microbiota

Transition to family foods drives development of infant gut microbiota

After the age of nine months, the development of the infant gut microbiota is driven by the transition to family foods, not maternal obesity, according to results from a new study. The study was published online this week in mSphere, an open-access journal of the American Society for Microbiology. [More]
Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes

Study identifies FGF21 protein as potential therapeutic agent for cardiovascular diseases, type 2 diabetes

New research on the blood lipid-lowering protein FGF21 shows how it redistributes fatty acids by two distinct mechanisms. The discovery could lead to improved pharmaceutical treatment for type 2 diabetes and other obesity-related diseases. [More]
New technique could help detect harmful PAMP molecules in certain processed foods

New technique could help detect harmful PAMP molecules in certain processed foods

Our favourite foods could be made healthier thanks to a new technique developed by the University of Leicester which has identified harmful bacterial molecules in certain processed foods such as burgers and ready meals. [More]
Study sheds light on role of red raspberries in metabolically-based chronic diseases

Study sheds light on role of red raspberries in metabolically-based chronic diseases

Components in red raspberries may have anti-inflammatory, anti-oxidative and metabolic stabilizing activity, according to a comprehensive review of the available scientific literature published in the January issue of Advances in Nutrition. [More]
Barley can help reduce blood sugar levels and diabetes risk

Barley can help reduce blood sugar levels and diabetes risk

A recent study from Lund University in Sweden shows that barley can rapidly improve people's health by reducing blood sugar levels and risk for diabetes. The secret lies in the special mixture of dietary fibres found in barley, which can also help reduce people's appetite and risk for cardiovascular disease. [More]
Certain gene variants influence what we eat

Certain gene variants influence what we eat

If you're fat, can you blame it on your genes? The answer is a qualified yes. Maybe. Under certain circumstances. Researchers are moving towards a better understanding of some of the roots of obesity. [More]
Loyola offers multidisciplinary digestive health program

Loyola offers multidisciplinary digestive health program

Loyola University Health System now offers a multidisciplinary digestive health program to treat digestive tract and related medical conditions. Bipan Chand, MD, FACS, FASGE, FASMBS, and Neil Gupta, MD, MPH, are co-directors of the new program. [More]
Vacations may lead to extra weight

Vacations may lead to extra weight

A week's vacation may leave many adults with a heavier midsection--extra weight that can hang around even six weeks post-vacation. [More]
ADHD increases risk of becoming obese

ADHD increases risk of becoming obese

With the incidence of obesity increasing steadily, much research has been undertaken to try and identify those people who are most likely to become obese so measures can be taken to avoid excessive weight gain, since it is easier to prevent than to reverse. [More]
Strong link found between incarceration of family members during childhood and heart attacks in men

Strong link found between incarceration of family members during childhood and heart attacks in men

A parent's incarceration has immediate, devastating effects on a family. Now, Virginia Tech and University of Toronto researchers say there may be a longer term risk: Men who as children experienced a family member's incarceration are approximately twice as likely to have a heart attack in later adulthood in comparison with men who were not exposed to such a childhood trauma. [More]
Growing up poor promotes eating in the absence of hunger in adulthood

Growing up poor promotes eating in the absence of hunger in adulthood

How much you eat when you're not really hungry may depend on how well off your family was when you were a child, according to new research published in Psychological Science, a journal of the Association for Psychological Science. [More]
Using BMI to measure health incorrectly labels over 54 million Americans as 'unhealthy', study finds

Using BMI to measure health incorrectly labels over 54 million Americans as 'unhealthy', study finds

Over the past few years, body mass index, a ratio of a person's height and weight, has effectively become a proxy for whether a person is considered healthy. Many U.S. companies use their employees' BMIs as a factor in determining workers' health care costs. And people with higher BMIs could soon have to pay higher health insurance premiums, if a rule proposed in April by the Equal Employment Opportunity Commission is adopted. [More]
New research shows link between childhood ADHD and obesity development during adulthood

New research shows link between childhood ADHD and obesity development during adulthood

The incidence of childhood and adult obesity has increased significantly over the past three decades. New research shows that there is an association between obesity development during adulthood and childhood attention deficit hyperactivity disorder (ADHD). [More]
One million serious medical complications could be avoided with improvements in blood glucose levels in diabetics

One million serious medical complications could be avoided with improvements in blood glucose levels in diabetics

Sanofi, Diabetes UK and JDRF today announce the publication of IMPACT 2 in the journal Diabetic Medicine. This new study shows that, if sustained, even modest improvement in blood glucose levels can provide significantly improved outcomes for the 3.5 million people diagnosed with diabetes in the UK. [More]
Potential treatment target identified for fatty liver disease

Potential treatment target identified for fatty liver disease

Two proteins, p38 gamma and p38 delta, control the accumulation of fat in the liver, a process linked to the development of insulin resistance and diabetes, which are common outcomes of obesity. These findings are presented in an article published by researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC). [More]
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