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Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.
UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat. [More]
Penn State dermatologist clarifies common myths about psoriasis

Penn State dermatologist clarifies common myths about psoriasis

Psoriasis is a much-misunderstood disease, often kept under wraps by sufferers who want to hide their skin lesions. [More]
Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Study suggests microRNAs may connect inflammation with heart disease risk in obese people

Inflammation likely plays a role in the increased risk of heart disease that comes with obesity, but scientists don't fully understand how obesity leads to heart disease. [More]
Arab uprising linked to detrimental effects on health and life expectancy in several countries

Arab uprising linked to detrimental effects on health and life expectancy in several countries

The Arab uprising in 2010 and subsequent wars in the eastern Mediterranean region have had serious detrimental effects on the health and life expectancy of the people living in many of the 22 countries in the region, according to a major new analysis from the Global Burden of Disease Study 2013 (GBD 2013), published in The Lancet Global Health journal. [More]
Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis. [More]
New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus

A disorder known as Barrett's esophagus (BE) affects some 200,000 Americans each year. The condition, which is caused by stomach acid damaging the lining of the esophagus, can lead to the development of a serious, potentially fatal cancer of epithelial tissue, known as esophageal adenocarcinoma. [More]
UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

UC San Francisco researchers studying beige fat — a calorie-burning tissue that can help to ward off obesity and diabetes — have discovered a new strategy to cultivate this beneficial blubber. [More]
Study reveals disadvantaged neighborhood puts teens at increased risk for being overweight or obese

Study reveals disadvantaged neighborhood puts teens at increased risk for being overweight or obese

A new Kaiser Permanente study found an increased risk for becoming overweight or obese among normal-weight 18-year-olds who lived in neighborhoods with lower education or income levels. [More]
Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. [More]
Scientists identify eight cancer types linked to excess weight and obesity

Scientists identify eight cancer types linked to excess weight and obesity

There's yet another reason to maintain a healthy weight as we age. An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma. [More]
Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. [More]
Avoiding foods high in AGEs could help protect from developing diabetes

Avoiding foods high in AGEs could help protect from developing diabetes

Simple changes in how we cook could go a long way towards preventing diabetes, say researchers at the Icahn School of Medicine at Mount Sinai. [More]
UT Southwestern researchers discover protein that can promote healthful breakdown of fat

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat. [More]
Study shows Latinos age more slowly at molecular level than other ethnic groups

Study shows Latinos age more slowly at molecular level than other ethnic groups

A new paper co-authored by a UC Santa Barbara researcher reveals that Latinos age at a slower rate than other ethnic groups. The findings, published in the current issue of Genome Biology, may one day help scientists understand how to slow the aging process for everyone. [More]
AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Scientists have proposed that inflammation is the harbinger of aging and central to the aging process, a phenomenon described as 'inflamm-aging,' said Dr. Yuxiang Sun. [More]
Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Can a diet high in processed fat and sugar and Type 2 diabetes cause degeneration of intervertebral discs in the spine? If so, what is happening, and can it be prevented? As part of an ongoing collaboration between Rensselaer Polytechnic Institute and the Icahn School of Medicine at Mount Sinai - a partnership that draws upon the expertise of both schools to address significant health problems - researchers hope to answer those questions by investigating the link between diet, obesity-linked Type 2 diabetes, and intervertebral disc degeneration. [More]
U-M study casts doubt on possible link between obesity and imbalance of microbes

U-M study casts doubt on possible link between obesity and imbalance of microbes

For people with weight problems, news headlines in recent years may have brought relief, as researchers studying the microscopic creatures inside our bodies reported possible links between obesity and an out-of-whack balance of microbes. [More]
Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Scientists have long known that infants born to women who are obese show higher risks of obesity, but they don't fully understand what boosts those risks. [More]
New MRI method detects low zinc levels to help identify healthy prostate tissue from cancer

New MRI method detects low zinc levels to help identify healthy prostate tissue from cancer

A novel MRI method that detects low levels of zinc ion can help distinguish healthy prostate tissue from cancer, UT Southwestern Medical Center radiologists have determined. [More]
Morbidly obese individuals more likely to experience heart failure, say researchers

Morbidly obese individuals more likely to experience heart failure, say researchers

A study by Johns Hopkins researchers of more than 13,000 people has found that even after accounting for such risk factors as high blood pressure, high cholesterol and diabetes, so-called morbid obesity appears to stand alone as a standout risk for heart failure, but not for other major types of heart disease. [More]
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