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Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.
Insulin signaling pathway has significant influence on the growth of glioblastomas

Insulin signaling pathway has significant influence on the growth of glioblastomas

Drugs that target insulin pathways to slow or stop the growth of brain tumors are going in the right direction but appear to be on the wrong track, according to new research at Rice University. [More]
MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

Michigan State University researchers, who were the first to suggest that high blood pressure could be caused by belly fat hormones "talking" with blood vessels in the abdomen, have received a nearly $7 million National Institutes of Health grant to further their work. [More]
Obesity in African-American men increases prostate cancer risk

Obesity in African-American men increases prostate cancer risk

Obesity has a profoundly different effect on prostate cancer risk in African-American as compared to non-Hispanic white men. Obesity in black men substantially increases the risk of low- and high-grade prostate cancer, while obesity in white men moderately reduces the risk of low-grade cancer and only slightly increases the risk of high-grade cancer, according to the first large, prospective study to examine how race and obesity jointly affect prostate cancer risk. [More]
Children who experience multiple traumatic events face risk of being hypertensive adults

Children who experience multiple traumatic events face risk of being hypertensive adults

Children who experience multiple traumatic events, from emotional and sexual abuse to neglect, have higher blood pressures as young adults than their peers, researchers report. [More]
DPS Health introduces Virtual Lifestyle Management, forms partnership with Stanford Patient Education Research Center

DPS Health introduces Virtual Lifestyle Management, forms partnership with Stanford Patient Education Research Center

DPS Health, a leader in digital behavior change interventions for emergent-risk populations, announced today the launch of its health self-management solution. Designed for health plans, providers systems and employers that are setting population health strategies for the emergent-risk population – adults with one or more pre-chronic or early-stage chronic conditions – the solution includes multi-channel consumer engagement to educate and enroll populations, Virtual Lifestyle ManagementTM to help individuals embrace healthy lifestyles, and a suite of condition-based, self-management programs to help the same individuals manage the impact of one or more conditions. [More]
High-fat diet can alter your muscle metabolism, new study finds

High-fat diet can alter your muscle metabolism, new study finds

You might think that you can get away with eating fatty foods for a few days without it making any significant changes to your body. Think again. After just five days of eating a high-fat diet, the way in which the body's muscle processes nutrients changes, which could lead to long-term problems such as weight gain, obesity, and other health issues, a new study has found. [More]
Health-related tweets may help predict hospital emergency room visits

Health-related tweets may help predict hospital emergency room visits

Twitter users who post information about their personal health online might be considered by some to be "over-sharers," but new research led by the University of Arizona suggests that health-related tweets may have the potential to be helpful for hospitals. [More]
Being underweight in middle age associated with increased dementia risk

Being underweight in middle age associated with increased dementia risk

Middle-aged people who are underweight (with a Body Mass Index [BMI] less than 20 kg/m2) are a third more likely to develop dementia than people of similar age with a healthy BMI, according to new research published in The Lancet Diabetes & Endocrinology journal. [More]
Breastfeeding not a cure-all front-line strategy to prevent obesity, research shows

Breastfeeding not a cure-all front-line strategy to prevent obesity, research shows

Biologic research does not support breastfeeding as a cure-all front-line strategy to prevent obesity. Yes, while breastfeeding is the optimal first food for a baby, it's not as simple to say that it will protect all children from becoming obese. [More]
Commercial weight-loss programs can make significant difference in overall health

Commercial weight-loss programs can make significant difference in overall health

New research published in the Annals of Internal Medicine finds that commercial weight-loss programs can offer significant weight loss after one year of participation when compared to a control group. Researchers led by Kimberly A. Gudzune, M D, MPH, found that participants achieved up to 4.9% mean total weight loss following one year of participation, which could be medically significant for many people with obesity or excess weight. [More]
Simple dietary intervention can help reduce weight gain

Simple dietary intervention can help reduce weight gain

A University of Calgary study has found that rats fed a fibre supplement while on a high fat and high sugar diet show a much lower weight gain than those who did not eat the fibre. A team of researchers from the university's Cumming School of Medicine and the Faculty of Kinesiology says the study helps scientists better understand the mechanisms of weight control and energy balance. [More]
TABS study: Older people can improve their health by reducing sitting time

TABS study: Older people can improve their health by reducing sitting time

"I feel lethargic when I sit all day," said Gerald Alexander, an 82-year-old retired social service worker among the 25 Group Health patients who participated in the Take Active Breaks from Sitting (TABS) pilot study. "I feel much peppier when I stand and take walks." [More]
Rhythm, Actavis announce initiation of relamorelin Phase 2b trial for treatment of diabetic gastroparesis

Rhythm, Actavis announce initiation of relamorelin Phase 2b trial for treatment of diabetic gastroparesis

Rhythm, a biopharmaceutical company, and Actavis plc, a leading global pharmaceutical company, announced today the initiation of a Phase 2b clinical trial assessing the efficacy and safety of relamorelin (RM-131), Rhythm's ghrelin agonist, for the treatment of gastroparesis in patients with type 1 and type 2 diabetes. [More]
Exercise benefits obese, overweight people with NAFLD

Exercise benefits obese, overweight people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD. [More]
New study analyses physical, psychological consequences of bariatric surgery

New study analyses physical, psychological consequences of bariatric surgery

Bariatric surgery, or reduction of gastric capacity, is one of the longer lasting options to achieve considerable weight loss in obese people. A Spanish researcher has participated in a study that confirms that the effects of this relatively complex medical surgery are not only physical, but also psychological. [More]
Study identifies gut immune system as new, effective target for diabetes

Study identifies gut immune system as new, effective target for diabetes

A commonly-used drug to treat inflammatory bowel disease, such as Crohn's disease, has been shown to lower blood sugar levels in obese mice, potentially identifying the gut immune system as a new and effective target in treating diabetes in humans. [More]
American Oil Chemists' Society honors UMass Amherst food scientist

American Oil Chemists' Society honors UMass Amherst food scientist

The American Oil Chemists' Society has honored University of Massachusetts Amherst food scientist Yeonhwa Park with the Timothy L. Mounts Award for her "significant and important contributions in the area of bioactive lipids and their impact on health conditions such as obesity, osteoporosis, arthritis and cardiovascular disease." [More]
Family stressors during childhood are associated with weight gain

Family stressors during childhood are associated with weight gain

Adolescent obesity is a national public health concern and, unchecked, places young people on a trajectory for a variety of health issues as they grow older. [More]
Breastfeeding is not a frontline strategy to prevent obesity, say researchers

Breastfeeding is not a frontline strategy to prevent obesity, say researchers

A new study supports human milk as the optimal first food for babies, but the study raises questions about whether breast milk protects children from becoming obese. [More]
Researchers discover genetic factors key to POMC cells

Researchers discover genetic factors key to POMC cells

The little voice inside your head that tells you to eat, or stop eating, isn't a little voice - it's actually a cluster of about 10,000 specialized brain cells. And now, an international team of scientists has found tiny triggers inside those cells that give rise to this "voice", and keep it speaking throughout life. [More]
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