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Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.
Chemical compound shows promise in treating rheumatoid arthritis

Chemical compound shows promise in treating rheumatoid arthritis

Montana State University researchers and their collaborators have published their findings about a chemical compound that shows potential for treating rheumatoid arthritis. [More]
UH pharmacy students receive awards for excellence in clinical skills, disease management

UH pharmacy students receive awards for excellence in clinical skills, disease management

University of Houston pharmacy students wrapped up the spring semester with awards for excellence in professional service, clinical skills and disease management, earning kudos at the state level from the Texas Society of Health-System Pharmacists. [More]
University of Missouri researchers identify key protein component that causes cystic fibrosis

University of Missouri researchers identify key protein component that causes cystic fibrosis

Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers from the University of Missouri have identified a key component in the protein that causes the disease. It is a finding that may lay the foundation for the development of new medications and improved therapies. [More]
Researchers uncover major link between human body clock and immune system

Researchers uncover major link between human body clock and immune system

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases, discovered collaborators at the Perelman School of Medicine at the University of Pennsylvania and Trinity College, Dublin. [More]
LABINDIA to promote Dotmatics’ scientific informatics solutions, services in India

LABINDIA to promote Dotmatics’ scientific informatics solutions, services in India

Dotmatics, the leading provider of scientific informatics solutions and services for the pharma, biotech, chemicals, agrochemicals and academia announced today that it has appointed LABINDIA as a distributor in India. [More]

CPhI Istanbul 2015 opens as Turkey continues to dominate the MENA pharma region

Turkey is fast emerging as a new hub for pharma manufacturing. This year, CPhI Istanbul will welcome more than 200 exhibitors from 23 Countries and over 4,000 visitors.. [More]
Experimental gene therapy holds promise against metastatic prostate cancer

Experimental gene therapy holds promise against metastatic prostate cancer

Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth. [More]
Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Increased vascular stiffness has been identified as an important part of hypertension in aging adults. Previous studies of aortic stiffness have focused on changes in structural proteins that alter the properties of vascular walls causing them to become rigid. [More]
Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty. [More]
Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is the delivery of DNA into a patient's cells to replace faulty or missing genes—or adds new genes—in an attempt to cure cancer or make changes so the body is better able to fight off disease. Scientists and clinicians have identified a number of different ways to do this, in an effort to correct malfunctioning or mutated genes. Many gene therapy clinical trials are ongoing to assess the safety and potential benefits in patients with rare diseases. [More]
New study identifies enzyme that causes obesity-related hypertension

New study identifies enzyme that causes obesity-related hypertension

Obesity is a serious health problem affecting approximately one-third of the adult population in the United States. Obese individuals have an increased risk of diabetes and cardiovascular disease, including hypertension. A recent study led by a University of Missouri researcher has identified the enzyme responsible for obesity-related hypertension -- a finding that could lead to new treatment options. [More]
Novel combination therapy shows promise in mouse models of advanced prostate cancer

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body's immune response, allowing the cancer to grow despite treatment. [More]
Research provides insights into the ability of FL118 to overcome treatment resistance

Research provides insights into the ability of FL118 to overcome treatment resistance

The latest research from the team that discovered the novel anticancer agent FL118 highlights distinctive characteristics of this small-molecule compound and provides insights into its ability to overcome the persistent problem of treatment resistance. In findings reported in Molecular Cancer, Fengzhi Li, PhD, of Roswell Park Cancer Institute, and colleagues provide new evidence that FL118 may be more effective than two structurally similar injectable drugs and, additionally, may be effective as an oral agent. [More]
Cocaine changes brain function, increases impulsive behaviors

Cocaine changes brain function, increases impulsive behaviors

The brain function of people addicted to cocaine is different from that of people who are not addicted and often linked to highly impulsive behavior, according to a new scientific study. [More]
TDF switch effective in Asian chronic HBV patients

TDF switch effective in Asian chronic HBV patients

Switching therapy to tenofovir disoproxil fumarate is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients. [More]

New clinical guide focuses on use and validity of public blood pressure kiosks

High blood pressure affects one in three adults in the United States, and blood pressure measurement is the first step toward accurate diagnosis and management of the disease. The Food and Drug Administration acknowledges shortcomings of many public blood pressure kiosks (i.e., those found in pharmacies and supermarkets) and recommends the public seek doctors' advice when using blood pressure kiosks. [More]
TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

TAXIS Pharmaceuticals' TXA709 compound shows promise in combating antibiotic resistance

TAXIS Pharmaceuticals, a drug-discovery company focused on developing a new class of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections, today announced the presentation of data demonstrating the promise of its lead clinical candidate, TXA709, in combating antibiotic resistance. [More]
Dan Theodorescu awarded Barringer Medal for distinguished contributions to urology

Dan Theodorescu awarded Barringer Medal for distinguished contributions to urology

Dan Theodorescu, MD, PhD, director of the NCI-designated University of Colorado Cancer Center and professor of Urology and Pharmacology at the University of Colorado School of Medicine was awarded the Barringer Medal this past Saturday from the American Association of Genitourinary Surgeons for his distinguished contributions to urology. [More]
Purdue University study sheds light on how decitabine drug reverses cell damage

Purdue University study sheds light on how decitabine drug reverses cell damage

A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment. [More]
Researchers describe natural mechanism that helps repair lesions in teeth

Researchers describe natural mechanism that helps repair lesions in teeth

Researchers at Inserm and Paris Descartes University have just taken an important step in research on stem cells and dental repair. They have managed to isolate dental stem cell lines and to describe the natural mechanism by which they repair lesions in the teeth. This fundamental discovery will make it possible to initiate unprecedented therapeutic strategies to mobilise the resident dental stem cells and magnify their natural capacity for repair. [More]
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