Pharmacology News and Research RSS Feed - Pharmacology News and Research

Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.
New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella. [More]
Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key. [More]
UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass Medical School scientist Gang Han, PhD, and his team have designed a new class of molecules used in photodynamic therapy that are able to direct lamp light deep into tissue to kill cancer tumors. [More]
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
Special article outlines recommended strategies to prevent Zika from blood transfusion

Special article outlines recommended strategies to prevent Zika from blood transfusion

As the Zika epidemic spreads to the United States, the potential for contracting the disease via blood transfusion has emerged as a serious concern. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
New mouse model provides key information for understanding cortical circuit development

New mouse model provides key information for understanding cortical circuit development

A day by day log of cortical electric activity in the mouse visual cortex was published in the Journal of Neuroscience by George Washington University researcher Matthew Colonnese, Ph.D. [More]
Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol. [More]
Specific milk protein may help strengthen the body's disease-fighting power, research reveals

Specific milk protein may help strengthen the body's disease-fighting power, research reveals

According to an innovative, new investigation published in Nutrition Journal, cow's milk containing only A2 protein has been shown to increase an essential antioxidant that may help strengthen the body's disease-fighting power. [More]
Kratom may be safer and less addictive than current treatments for pain, research suggests

Kratom may be safer and less addictive than current treatments for pain, research suggests

A delayed U.S. Drug Enforcement Administration ban on kratom would stifle scientific understanding of the herb's active chemical components and documented pharmacologic properties if implemented, according to a special report published today in The Journal of the American Osteopathic Association. [More]
Acne: when to seek help?

Acne: when to seek help?

Acne develops due to an interplay between genetic factors (so people often have a family history) and hormonal factors that can increase the size and activity of the sebaceous or oil gland. [More]
Moderate coffee consumption may offer protection against age-related cognitive decline

Moderate coffee consumption may offer protection against age-related cognitive decline

A new report from the Institute for Scientific Information on Coffee (ISIC), a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health, highlights the potential role of coffee consumption in reducing the risk of cognitive decline. [More]
Editing preferences of enzymes may play role in infertility and cancer

Editing preferences of enzymes may play role in infertility and cancer

To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. [More]
Study explores link between feeding behavior and alcohol consumption

Study explores link between feeding behavior and alcohol consumption

Laboratory rats will drink alcohol if it's available, and may even get a little tipsy, researchers report in a new study. [More]
ADD Program receives $19.5 million NIH contract to test drugs for treating epilepsy

ADD Program receives $19.5 million NIH contract to test drugs for treating epilepsy

The University of Utah College of Pharmacy's Anticonvulsant Drug Development Program has been awarded a five-year $19.5 million contract renewal with the National Institutes of Health to test drugs to treat epilepsy, and the major focus of the project is to address needs that affect millions of people worldwide -identify novel investigational compounds to prevent the development of epilepsy or to treat refractory, or drug-resistant, epilepsy. [More]
Low-calorie diet and exercise could improve kidney function in patients with NASH

Low-calorie diet and exercise could improve kidney function in patients with NASH

Non-alcoholic steatohepatitis (NASH) is a potentially serious liver condition characterized by excess fat in the liver associated with inflammation and scarring. [More]
Researchers identify protein that plays key role in LDL accumulation in blood vessels

Researchers identify protein that plays key role in LDL accumulation in blood vessels

A Yale-led research team identified a protein that plays an important role in the buildup of LDL cholesterol in blood vessels. [More]
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