CN-Bio provides standard and tailored in vitro investigations to screen innovative therapeutic candidates, research mechanisms of action, and expedite clinical trial design. Their services are suitable for drug developers who want immediate access to organ-on-a-chip (OOC) technology without having to invest in equipment.
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Partner with CN-Bio to gain access to over a decade of OOC knowledge, the most human-relevant in vitro models available, a committed team of creative problem solvers, and a proven track record of producing clinically translatable solutions.
The dedicated contact will collaborate with users to plan and conduct research that yields findings more rapidly and cost-effectively than animal investigations. All studies use PhysioMimix® technology to create human-relevant data, which increases the likelihood of clinical success.
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NAFLD/NASH services
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Utilize the complimentary service to overcome the drawbacks of murine models and gain insight into the effectiveness of novel anti-NASH therapies in humans. Learn about the mechanisms underlying various disease markers, such as fibrosis, inflammation, and hepatic steatosis, and their target pathways.
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Drug-induced liver injury services
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The DILI Services provide a trustworthy instrument for assessing drug safety in a system relevant to humans. Using a broad range of clinically relevant endpoints, we can assess multiple endpoints to determine causality and the mechanism of toxicity, thereby establishing a comprehensive assessment of acute or chronic DILI risk.
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ADME services
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To understand the ADME characteristics of a broad range of drug modalities, we must go beyond what is currently achievable by determining the metabolites unique to humans and their relationship to cell health or selecting candidates with desired profiles by more precisely predicting bioavailability compared to animal models.
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