Archived Medical News Stories

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RSSArchived Drug Trial News Stories - May 2012

Date Title Comments Rating
2012-05-31 Ketamine reduces suicidal thoughts in patients with bipolar depression 0 None
2012-05-31 Taiho to initiate TAS-102 Phase III trial in colorectal cancer 0 None
2012-05-31 Top-line data from Flexion‘s FX005 Phase 2 trial on osteoarthritis 0 None
2012-05-31 Stiefel to acquire WBI-1001 licensing rights from Welichem 0 None
2012-05-31 CTI announces results from PIX301 phase 3 trial of Pixuvri for NHL 0 None
2012-05-31 Wellmune minimizes risk of URTI among marathoners 0 None
2012-05-31 Top-line results from Alnylam’s ALN-RSV01 Phase IIb trial on RSV infection 0 None
2012-05-31 Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation 0 None
2012-05-31 Exelixis commences cabozantinib phase 3 pivotal trial in mCRPC 0 None
2012-05-30 Corrected interim data from Vertex VX-809, KALYDECO combination Phase 2 study for CF 0 None
2012-05-30 DMARD not superior to oral therapy in long-term treatment of patients with JIA 0 None
2012-05-30 CytRx INNO-206 doxorubicin conjugate shows anti-multiple myeloma effects 0 None
2012-05-30 JTCC to present latest findings in blood-cancer research at ASCO annual meeting 0 None
2012-05-30 Positive results from RedHill’s RHB-103 bioequivalence trial on acute migraine 0 None
2012-05-30 Marshall Edwards initiates ME-344 Phase I trial in solid tumors 0 None
2012-05-30 NAC may be an effective therapy for some features of autism 0 None
2012-05-30 Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD 2 None
2012-05-29 FDA accepts NDA filing for KYNAMRO to treat HoFH 0 None
2012-05-29 Oncos Therapeutics commences clinical study with oncolytic viruses 0 None
2012-05-29 Spectrum initiates enrollment in RenaZorb Phase 1 trial in healthy volunteers 0 None
2012-05-29 Enrollment complete in Advaxis’ ADXS-HPV Phase 2 trial for cervical cancer 0 None
2012-05-29 Abbott to highlight latest investigational research findings on HUMIRA at EULAR 2012 0 None
2012-05-28 Positive results from Acacia Phase II APD421 study in prevention of post-operative nausea & vomiting 0 None
2012-05-28 Medivir initiates MIV-711 phase I trial in bone disorders 0 None
2012-05-28 AngioPredict project to focus on patients with metastatic colorectal cancer 0 None
2012-05-28 Tβ4 offers both neurorestoration and neuroprotection after TBI 0 None
2012-05-28 Positive results from Sanofi and Regeneron’s SAR236553/REGN727 Phase 2 trial on heFH 0 4
2012-05-28 ESRD patients with diabetes may benefit from Baxter’s low-glucose PD regimen 0 None
2012-05-25 Linagliptin safe and effective for African American patients with type 2 diabetes 0 None
2012-05-24 Insmed initiates patient screening for ARIKACE phase 2 NTM lung disease trial 0 None
2012-05-24 ICS may prevent parapneumonic effusion in patients with CAP 0 None
2012-05-24 Preliminary results from Celldex’s CDX-011 Phase 2b breast cancer study 0 None
2012-05-24 Azithromycin can be effective treatment option for patients with BOS 0 None
2012-05-24 Molecular Therapy releases characteristics and activity of SNS01 formulation 0 None
2012-05-23 Phase I/II clinical trial of novel dialysate completed by Zytoprotec 0 None
2012-05-23 AVEO commences AV-203 Phase 1 study in advanced solid tumors 0 None
2012-05-23 Researchers to initiate Crenezumab clinical trial to treat Alzheimer's 0 None
2012-05-23 New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer 0 None
2012-05-23 HVTN opens enrollment in GeoVax’s GM-CSF adjuvanted vaccine Phase 1 trial for HIV 0 None
2012-05-23 Daily use of vitamin C by smoking pregnant woman improves pulmonary function in babies 0 None
2012-05-23 Results from Boehringer Ingelheim’s Respimat Phase II study on moderate, persistent asthma 0 None
2012-05-23 Benefits of ICS treatment vary among children with differing demographic, clinical characteristics 0 None
2012-05-23 Data from Alvine’s ALV003 Phase 2A trial on celiac disease presented at DDW 2012 0 None
2012-05-22 Combination therapy does not reduce mortality rates associated with severe sepsis 0 None
2012-05-22 Gattex may represent new treatment approach for short bowel syndrome 0 None
2012-05-22 Diamyd Medical completes enrollment in NP2 Enkephalin Phase II study for cancer pain 0 None
2012-05-22 Bayer’s Nexavar Phase 3 trial on NSCLC does not meet primary endpoint 0 None
2012-05-22 New research reveals effective treatments for gastrointestinal conditions 0 None
2012-05-22 Enrollment complete in Xencor, MorphoSys’ MOR208 phase 1 trial for CLL 0 None
2012-05-22 Data from Janssen’s SIMPONI Phase 3 study on ulcerative colitis 0 5
2012-05-21 AltheRx reports positive Phase II results of Solabegron for OAB 0 None
2012-05-21 SERVE-HF study on effect of CSA treatment for stable heart failure enrolls 1,000th participant 0 None
2012-05-21 Ipsen, Active Biotech complete half of planned recruitment in tasquinimod phase III study for CRPC 0 None
2012-05-21 Hypertonic saline does not reduce rate of pulmonary exacerbations in young children with CF 0 None
2012-05-21 Statin therapy prevents cancer and reduces death risk in heart transplant recipients 0 None
2012-05-21 Oxytocin increases brain activations in children and adolescents with ASD 0 None
2012-05-21 Three-drug combo harmful for patients with idiopathic pulmonary fibrosis 0 None
2012-05-21 POZEN presents data from PA32540 Phase 1 gastric acid reduction study at DDW 2012 0 None
2012-05-19 Santarus to present UCERIS Phase III trial data on ulcerative colitis at DDW meeting 0 5
2012-05-19 Receptos to present scientific podium presentation about RPC1063 at DDW 2012 0 None
2012-05-19 Ceregene announces new data from CERE-120 clinical trial on Parkinson's 0 None
2012-05-19 Data from Purdue Pharma’s Butrans clinical trials to be presented at APS annual meeting 0 None
2012-05-19 Pfizer announces results from Lyrica clinical studies on fibromyalgia 1 5
2012-05-19 Data from Almirall, Forest Labs’ aclidinium studies on COPD to be presented at ATS conference 0 None
2012-05-19 Biovest announces new data from BiovaxID Phase II mantle cell lymphoma trial 0 None
2012-05-19 Daiichi Sankyo, ArQule complete enrollment in tivantinib plus erlotinib Phase 3 NSCLC trial 0 None
2012-05-19 Sigmoid provides financial and product development update 0 None
2012-05-18 ArQule to present positive tivantinib Phase 2 clinical data for hepatocellular carcinoma 0 None
2012-05-18 Urocortin 2 improves cardiac output in Phase II study for acute decompensated heart failure 0 None
2012-05-18 Breast cancer vaccine that elicits powerful immune response also improves recurrence rates 0 None
2012-05-18 Pharmacyclics announces clinical abstracts on ibrutinib to be presented at ASCO annual meeting 0 None
2012-05-18 Ipsen, Active Biotech to present data from tasquinimod phase II trial on CRPC at ASCO 2012 0 None
2012-05-18 Potential public-private partnership aims to bring TB vaccine trials to mines of Southern Africa 0 None
2012-05-18 Janssen’s NUCYNTA ER tablets more effective in providing pain management in adults with DPN 0 None
2012-05-18 Avraham initiates ladostigil Phase 2 trial in MCI 0 None
2012-05-18 Dabrafenib drug shrinks tumors in patients with melanoma brain metastases 0 None
2012-05-18 Patients with muscle-invasive bladder cancer benefit from accelerated MVAC 0 5
2012-05-18 Esperance initiates enrollment in EP-100 and paclitaxel Phase 2 combination trial for ovarian cancer 0 None
2012-05-18 Additional data from Tokai’s galeterone Phase 1 study on CRPC 0 None
2012-05-18 Pharmos completes levotofisopam phase 2a trial on hyperuricemia, gout 0 None
2012-05-18 Spectrum initiates ZEVALIN and MGd Phase 2 combination study in NHL 0 None
2012-05-17 Inovio SynCon avian influenza vaccine demonstrates broad coverage 0 None
2012-05-17 Lenalidomide following stem cell transplant can halt progression of blood cancer 0 None
2012-05-17 CHOP researcher leads trial of ALK inhibitor in neuroblastoma, lymphoma 0 None
2012-05-17 Abiraterone acetate can help eliminate prostate tumors 0 None
2012-05-17 First trial to investigate new drug combination for NSCLC 0 None
2012-05-17 PCSO-524 omega-3 complex may provide benefits for joint mobility and pain 0 None
2012-05-17 Treating prenatal maternal infections could improve birth outcomes, study suggests 0 None
2012-05-17 Updated results from Amgen’s blinatumomab Phase 2 study on ALL 0 None
2012-05-17 Ibrutinib shows promise against CLL in the elderly 0 None
2012-05-17 Data from Jennerex JX-594 clinical trials on cancer to be presented at ASCO annual meeting 0 None
2012-05-17 Reformulated anti-HIV gel may be safe for use in both vagina, rectum 0 None
2012-05-17 No significant differences in absorption between tablet and softgel capsule forms of folic acid 0 None
2012-05-17 Combination of daclizumab and vaccine improves survival of breast cancer patients 0 None
2012-05-17 May issue of NeuroPerspective assesses field of stroke therapeutics 0 None
2012-05-17 Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC 0 None
2012-05-16 Most depressed patients must make multiple attempts before finding an effective antidepressant 0 None
2012-05-16 First patient included in the phase II study of Amphinex® in head and neck cancer patients 0 None
2012-05-16 Achaogen’s plazomicin and levofloxacin safe and effective in treating cUTI, acute pyelonephritis 0 None
2012-05-16 Pfizer fails to meet primary endpoint in TORISEL Phase 3 study for advanced RCC 0 None
2012-05-16 Galectin Therapeutics commences Phase 1/2 trial of new treatment combination for advanced MM 0 4
2012-05-16 Positive data from Theraclone Sciences’ TCN-032 Phase 1 trial on influenza A infection 0 None
2012-05-16 Juventas begins enrollment in JVS-100 Phase IIa study for Rutherford Class 4 or 5 CLI 0 None
2012-05-16 Novelos completes I-131-CLR1404 Phase 1b trial on advanced solid tumors 0 None
2012-05-15 Svelte completes enrollment in DIRECT drug-eluting stent study 0 None
2012-05-15 Cubist announces results from CB-5945 Phase 2 studies on chronic non-cancer pain, OIC 0 None
2012-05-15 Pearl Therapeutics to present PT003 Phase 2b study on COPD at ATS meeting 0 None
2012-05-15 Smoked cannabis may be an effective treatment for spasticity 0 None
2012-05-15 BioAlliance Pharma commences Livatag phase III trial in hepatocellular carcinoma 0 None
2012-05-15 Lilly to present oncology data from more than 25 studies at ASCO annual meeting 0 None
2012-05-15 Fibrocell submits azficel-T Phase II study protocol with FDA to treat restrictive burn scars 0 None
2012-05-14 Phase II trial to examine effects of resveratrol on individuals with mild to moderate dementia 0 None
2012-05-14 Top-line data from S.L.A. Pharma’s Nalcol Phase 2 study on OIC 0 None
2012-05-14 Lenalidomide delays progression of multiple myeloma after stem cell transplant 0 None
2012-05-14 Chronic asthma sufferers may have new hope for relief due to two BWH research studies 0 None
2012-05-11 Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD 0 None
2012-05-11 Arno AR-42 for neurofibromatosis type 2 receives EMA orphan-drug designation 0 None
2012-05-11 Top-line results from Takeda vedolizumab phase 3 trial on Crohn's disease 0 None
2012-05-11 Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis 0 None
2012-05-11 Interim results from Seattle Genetics’ ADCETRIS phase II trial on CTCL 0 None
2012-05-11 NEJM publishes results from Celgene’s REVLIMID phase III studies on MM 0 None
2012-05-11 Rituximab does not appear to benefit children with INS 0 None
2012-05-11 Onconova advances rigosertib into new Phase II study for refractory MDS 0 None
2012-05-10 Macrocure's CureXcell Shows Strong Efficacy and Safety in Phase IV Hard-To-Heal Wounds Trial 0 None
2012-05-10 Fast track approval process for “breakthrough” drugs proposed in the U.S. 0 None
2012-05-10 Leishmaniasis vaccine trial begins in U.S., India 0 None
2012-05-10 Hygieia’s DIGS automatically adjusts insulin dosage in patients with diabetes 0 None
2012-05-10 Sunovion announces results from LATUDA open-label study for schizophrenia 0 None
2012-05-10 Lenalidomide improves overall survival for patients with multiple myeloma 0 None
2012-05-10 IDRI, Aeras partner to develop new TB vaccine candidate 0 None
2012-05-10 Resverlogix completes RVX-208 Phase 2b trial on CVD 0 None
2012-05-10 Janssen submits XARELTO sNDA with FDA to reduce risk of stent thrombosis in ACS patients 0 None
2012-05-09 New study to measure effectiveness of Vitamin B12 in preventing gestational diabetes 0 None
2012-05-09 Provectus announces final data from PV-10 Phase 2 trial on metastatic melanoma 0 None
2012-05-09 Sildenafil may improve cardiac function in children, young adults with single ventricle defects 0 4.5
2012-05-09 Antidepressives reduce risk of suicides in schizophrenic patients 0 None
2012-05-09 Two studies suggest long-term value of Deplin in treating MDD 0 5
2012-05-08 Rexahn submits Phase II protocol for Archexin clinical study for ovarian cancer 0 None
2012-05-08 Advaxis commences enrollment in ADXS-HPV Phase 1/2 study for head and neck cancer 0 None
2012-05-08 Certain males at higher risk of infection after receiving experimental HIV vaccine 0 None
2012-05-08 Oral zinc treatments may shorten duration of common cold symptoms in adults 0 None
2012-05-08 Everett Labs announces availability of Pregnitude for women with fertility problems 0 None
2012-05-08 Pall in-line filters can reduce severe complications, length of hospital stay in PICU 0 None
2012-05-08 New data from Acucela’s ACU-4429 Phase 2a trial on advanced dry AMD/geographic atrophy 1 None
2012-05-08 Otsuka announces results from aripiprazole Phase 3 trial on schizophrenia 0 None
2012-05-07 Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency 0 None
2012-05-07 NovaDigm reports positive data from Phase 1 NDV-3 vaccine program 0 None
2012-05-07 Galleon GAL-021 safe and well-tolerated in Phase I respiratory depression clinical study 0 None
2012-05-07 Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting 0 None
2012-05-07 Positive results from Dainippon Sumitomo Pharma's LATUDA trials for bipolar I depression 0 None
2012-05-07 KYTHERA ATX-101-10-16 trial for submental fat meets primary endpoints 0 None
2012-05-07 BioCryst first quarter revenues increase to $12.2 million 0 None
2012-05-05 Clinical data from Anacor’s tavaborole and AN2728 study to be presented at upcoming meetings 0 None
2012-05-05 Ocular Therapeutix initiates travoprost-loaded punctum plug trial in glaucoma 0 None
2012-05-05 Teva announces new data from women's health franchise 0 None
2012-05-05 Flavan-3-ols, SoyLife can improve biomarkers of CVD risk in postmenopausal type 2 diabetic patients 0 None
2012-05-05 Pfizer terminates Lyrica Phase 3 trial on neuropathic pain associated with HIV neuropathy 0 None
2012-05-05 Isis commences ISIS-APOCIIIRx Phase 2 study in hypertriglyceridemia 0 None
2012-05-05 Pfizer’s Lyrica Phase 3 study on pDPN fails to meet primary endpoint 0 None
2012-05-04 New analysis may help identify breast cancer patients who will benefit from immune suppressant 0 None
2012-05-04 CSL Behring commences C1-INH phase I/II study in hereditary angioedema 0 None
2012-05-04 Generon commences F-627 Phase II trial in breast cancer 0 None
2012-05-04 Abbott to purchase AP214 hormone analogue from Action Pharma 0 None
2012-05-04 Clinical trial to investigate statins in patients with acute severe respiratory failure 0 None
2012-05-04 Varenicline reduces alcohol intake among heavy-drinking smokers 0 None
2012-05-04 Lexicon to receive funding for LX4211 Phase 2 trial in type 1 diabetes 0 None
2012-05-04 GenVec receives NIAID’s Phase I SBIR grant to support RSV vaccine program 0 None
2012-05-04 NCIC CTG, Oncolytics to conduct REOLYSIN Phase II study in colorectal cancer 0 None
2012-05-03 HiLo trial sets new gold standard for thyroid cancer treatment 0 4
2012-05-03 SC formulation of Genentech’s ACTEMRA shows promise against RA 0 None
2012-05-03 Physician Therapeutics publishes results from Sentra PM clinical trial 0 None
2012-05-02 German BfArM grants Moberg Derma approval to initiate Limtop phase II actinic keratosis trial 0 None
2012-05-02 ImmuVen awarded $1.68M NIH Phase II SBIR grant to develop IMV0123 0 None
2012-05-02 Fish oil may improve outcomes for kidney patients undergoing hemodialysis 1 None
2012-05-02 JLGTD to publish results from Cutaneous Lysate study on vulvodynia 0 None
2012-05-02 Topline, interim results from Celldex Phase 2b EMERGE study of CDX-011 for advanced breast cancer 0 None
2012-05-02 Ultragenyx reports results from UX001 Phase 1 study on HIBM 0 None
2012-05-02 Inovio's SynCon vaccine for cervical dysplasias and cancers granted U.S. patent 0 None
2012-05-02 Sanofi Pasteur announces new quadrivalent influenza vaccine Phase III pediatric data 0 None
2012-05-02 Bevacizumab equivalent to ranibizumab in treating wet AMD 0 None
2012-05-02 CHR-3996 pill shows promise against advanced cancers 0 None
2012-05-02 Lixte submits IND with FDA to conduct LB-100 Phase I trial for cancer 0 None
2012-05-02 Gilead commences GS-1101 Phase 3 trial in CLL 0 None
2012-05-02 ACE inhibitors or ARBs could treat and prevent PTSD 0 None

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