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Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

19 Oct 2015

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

19 Oct 2015

OSU discovery sheds new light on how proteins fold

Biochemists at Oregon State University have made a fundamental discovery about protein structure that sheds new light on how proteins fold, which is one of the most basic processes of life.

19 Oct 2015

Camels in Kenya infected by MERS virus, new study finds

A new study has found that nearly half of camels in parts of Kenya have been infected by the virus that causes Middle East Respiratory Syndrome (MERS) and calls for further research into the role they might play in the transmission of this emerging disease to humans.

19 Oct 2015

Reward and daytime nap combo key to learning, new study suggests

A new study suggests that receiving rewards as you learn can help cement new facts and skills in your memory, particularly when combined with a daytime nap.

19 Oct 2015

More research needed on commercially available nutrigenomics tests: Study

There is insufficient scientific evidence to support the utility of commercially available nutrigenomics tests that claim to link genetic variants to dietary intake or nutrition-related disorders.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

The New York Stem Cell Foundation and Cbr Systems, Inc. DBA Cord Blood Registry today announced a collaboration to customize the creation of high-quality stem cell lines. NYSCF will create induced pluripotent stem (iPS) cell lines from umbilical cord tissue collected after birth from healthy newborns provided by CBR.

19 Oct 2015

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

Neural stem cells transplanted into damaged brain sites in mice dramatically improved both motor and cognitive impairments associated with dementia with Lewy bodies, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

The key to immune-based cancer therapies lies in the ability to exploit some weakness within the tumor and its environment or to elude cancer's offenses. Writing in the journal Scientific Reports, researchers led by a group from the Roswell Park Cancer Institute Center for Immunotherapy have shared new insights about a subset of T cells that appear to do both those things, inhibiting cancer growth at the same time that they enhance the tumor-killing powers of other immune cells.

19 Oct 2015

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

A research group at Tohoku Medical Megabank Organization (ToMMo) has successfully constructed a Japanese population reference panel (1KJPN), from the genome information of 1,070 individuals who had participated in the cohort studies of the Tohoku Medical Megabank Project.

19 Oct 2015

CNIO researchers identify molecular mechanisms that determine cancer predisposition in DBA patients

Researchers from the Tumour Suppression Group at the Spanish National Cancer Research Centre, headed by Manuel Serrano, have discovered the molecular mechanisms that determine cancer predisposition in patients with Diamond-Blackfan anaemia (DBA).

18 Oct 2015

New UCL study highlights genes associated with schizophrenia and obesity

Genes involved in schizophrenia and obesity have been highlighted in a new UCL study, which could lead to a better understanding of the DNA variants which affect risk of these conditions and aid the development of improved strategies for prevention and treatment.

18 Oct 2015

New zebrafish study provides insights into causes of congenital heart defects

Researchers working with zebrafish at New Zealand's University of Otago have published a study providing new insights into the causes of the congenital heart defects associated with a rare developmental disorder.

16 Oct 2015

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating blood cells and opens up a new avenue for reducing their progressive functional decline with age.

16 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

NEB releases new NEBNext Ultra II DNA Library Prep Kit

New England Biolabs today announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina next generation sequencing systems. The new Ultra II kit substantially improves upon its predecessor to produce libraries of both higher quality and higher yield from a variety of sample types, including challenging ones, such as formalin-fixed, paraffin-embedded (FFPE) samples and those containing low amounts of input DNA.

From New England Biolabs 16 Oct 2015

Brown University researchers describe new method to test HIV mutations

Tests that can distinguish whether HIV-positive people are infected with a drug-resistant strain or a non-resistant strain allow patients to get the most effective treatment as quickly as possible. In the November edition of the Journal of Molecular Diagnostics, a team of Brown University researchers describes a new method that works faster and more sensitively in lab testing than the current standard technologies.

16 Oct 2015

Medical Science News

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

OSU discovery sheds new light on how proteins fold

Camels in Kenya infected by MERS virus, new study finds

Reward and daytime nap combo key to learning, new study suggests

More research needed on commercially available nutrigenomics tests: Study

New research shows nicotine increases codeine-induced analgesia

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

Researchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodies

BET protein family plays key role in regulation of normal neuronal development and function

Special CD4+ T cells appear to inhibit cancer growth, enhance tumor-killing powers of other immune cells

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

CNIO researchers identify molecular mechanisms that determine cancer predisposition in DBA patients

New UCL study highlights genes associated with schizophrenia and obesity

New zebrafish study provides insights into causes of congenital heart defects

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

New research raises hope for novel cancer immunotherapy

NEB releases new NEBNext Ultra II DNA Library Prep Kit

Brown University researchers describe new method to test HIV mutations

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

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