Bipolar Disorder

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Symptoms of bipolar disorder are severe.

The Genetics of Mental Disorder

No psychiatric or mental disorder has a fully genetic basis or heritability, and many environmental factors may influence the likelihood of a particular disorder.

What is Olanzapine?

Generalized Anxiety Disorder Comorbidities

Bipolar Disorder

Bipolar Disorder Symptoms

Bipolar Disorder Diagnosis

Bipolar Disorder Treatment

Bipolar Disorder Interventions

Bipolar Disorder Counseling

Intermittent Explosive Disorder Causes

Bipolar Disorder and Parkinson’s

What is Schizoaffective Disorder?

Latest Bipolar Disorder News and Research

Many ADHD trials in adults lack proper diagnostic standards

Millions of adults around the world are diagnosed with ADHD every year, and there is a great need for research in the field.

1 Jul 2025

New study reveals how diverse brain cells unite to guide decisions

Every decision begins invisibly. Long before someone acts, the brain is already hard at work gathering evidence, weighing options, and gradually committing to a choice.

27 Jun 2025

TET1 identified as key regulator in cancer and chronic disease

Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases.

25 Jun 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Rising temperatures linked to more severe sleep apnea worldwide

Sleep apnea will become more common and more severe due to global warming, leading to increased health and economic burdens across the globe, warn Flinders University sleep experts.

16 Jun 2025

Bitter 'supertaster gene' tied to bipolar disorder and poor kidney function

People who carry a bitter 'supertaster gene' have been linked to various health conditions including bipolar disorder and poor kidney function, University of Queensland researchers have found.

12 Jun 2025

Physical comorbidities from mental illness drive up hospital strain in Europe

A recent study led by Judit Simon from the Department of Health Economics, Center for Public Health, at the Medical University of Vienna shows for the first time comprehensively the extent to which people with mental disorders suffer from physical illnesses - and the resulting hospital costs.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Late-life mood disorders may signal neurodegenerative diseases

Depression and bipolar disorder of late onset may represent more than just mental health conditions. Growing evidence suggests these late-life mood disorders (LLMDs) could be not merely risk factors, but rather early warning signs of neurodegenerative diseases like dementia, even when they appear years before memory loss or other cognitive symptoms become apparent.

9 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

Researchers show cannabis dependence drives links to psychiatric disorders

Research uncovers genetic connections between cannabis addiction and psychiatric disorders, urging a reevaluation of cannabis legalization and treatment.

2 Jun 2025

Study shows elevated risk of psychopathology in children of people with schizophrenia or bipolar disorder

A new study confirms that children of people with schizophrenia or bipolar disorder have a higher risk of developing psychopathology compared to children whose parents do not have these conditions.

21 May 2025

Detailed personality tests may help personalize care for people with bipolar disorder

People with cancer, heart disease and other conditions have come to expect treatments that their medical teams "personalize" just for them, based on tests.

16 May 2025

Californians receiving in-home care fear Medicaid cuts will spell end to independent living

With a Starbucks coffee cup in her hand and a half gallon of milk under her arm, Florence Owens let herself into Carol Crooks' apartment on a Monday morning, announced herself with a cheery "hello," walked through the book-filled living room, and got to work in the kitchen.

16 May 2025

Early vitamin D deficiency increases risk of ADHD, schizophrenia and autism

Newborn babies with a vitamin D deficiency have a higher chance of later developing mental disorders such as ADHD, schizophrenia and autism, a major study involving The University of Queensland has found.

14 May 2025

GLP-1 receptor agonists improve mood and metabolic health in adults with mental illness

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can lead to significant weight loss and improve blood sugar control in adults with severe mental illness, as well as having positive effects on mood, well-being, and quality of life in those both with and without mental illness, according to a systematic review of the available evidence being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

Women with serious mental illness need more support and education during menopause transition

Many women struggle to find resources to help manage their menopause symptoms. For women living with a serious mental illness, the need for additional support and education during the menopause transition is even greater.

7 May 2025

Mental health disorders tied to growing number of cannabis-related hospital visits

More people are landing in the hospital with cannabis-related problems-and for many, a mental health condition is the primary issue, according to a new study published in the Journal of Studies on Alcohol and Drugs.

7 May 2025

Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response

A randomized controlled trial shows that lithium treatment in bipolar disorder patients reduces daytime activity, advances its onset time, and increases volatility in circadian rest-activity patterns. These changes appear early and independently of mood, offering promise as early biomarkers of treatment response.

14 Apr 2025