Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Today (16 March 2023), Cystic Fibrosis (CF) Syndicate in Antimicrobial Resistance (AMR) announces a £3 million Collaborative Discovery Programme for drug discovery innovators to accelerate the development of new treatments for people with CF.

20 Mar 2023

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Patients with cystic fibrosis (CF) face difficulty breathing and a decline in lung function and are at risk of early death. CF is an inherited condition that results in thick mucus build-up, persistent infection and inflammation in the lungs.

15 Mar 2023

A review on two novel eating disorders

Researchers review existing data on avoidant/restrictive food intake disorder (ARFID) and atypical-type anorexia nervosa (AN).

13 Mar 2023

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

Researchers explored microfluidic systems with a skin interface in assessing chemical exposure and health status.

27 Feb 2023

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease.

22 Feb 2023

Machine learning algorithm predicts DNA insertion efficiency of prime editing

A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute.

15 Feb 2023

9 out of every 10 people hospitalized with the flu have at least one underlying medical condition

Leading health organizations are urging people to get a flu shot if they haven't already done so. Compared to last year's mild flu season, the U.S. has already seen more than three times the number of flu-related deaths.

6 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

AI tool promises to accelerate the development of gene therapies on a large scale

An artificial intelligence (AI) program may enable the first simple production of customizable proteins called zinc fingers to treat diseases by turning genes on and off.

26 Jan 2023

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

23 Jan 2023

Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Hospital financial decisions play a role in the critical shortage of pediatric beds for RSV patients

The dire shortage of pediatric hospital beds plaguing the nation this fall is a byproduct of financial decisions made by hospitals over the past decade, as they shuttered children's wards, which often operate in the red, and expanded the number of beds available for more profitable endeavors like joint replacements and cancer care.

9 Dec 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine researchers continue to report on new findings from the landmark transplant.

14 Nov 2022

What is the role of adenoviruses in human health?

With advances in molecular biology informing recent developments in vaccinology, gene therapy, and other fields of medicine, human adenoviruses (HAdVs) have been of primary importance in medical research. A recent review looks at the promises of HAdVs, their potential dangers, and future challenges.

9 Nov 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

A review on two novel eating disorders

Using sweat to diagnosis disease: soft microfluidic analysis systems assess health status

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

Machine learning algorithm predicts DNA insertion efficiency of prime editing

9 out of every 10 people hospitalized with the flu have at least one underlying medical condition

Novel tool uses AI to predict the efficacy of genome-editing repair options

AI tool promises to accelerate the development of gene therapies on a large scale

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

Understanding the mechanisms involved in heart disease and cancers

Cystic fibrosis drug shows promise to treat pneumonia

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

How human cell atlases provide the missing links between genes, diseases and therapies

Hospital financial decisions play a role in the critical shortage of pediatric beds for RSV patients

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

What is the role of adenoviruses in human health?

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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