Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

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Latest Lupus News and Research

Vitiligo linked to increased risk of heart disease and stroke, study finds

Vitiligo linked to increased risk of heart disease and stroke, study finds

Novel antibodies show promise for tumor targeting and RAD51 inhibition

Novel antibodies show promise for tumor targeting and RAD51 inhibition

New study reveals mechanism of inflammation in lupus

New study reveals mechanism of inflammation in lupus

The new science behind the health benefits of caffeine

The new science behind the health benefits of caffeine

Caffeine's anti-inflammatory effects may help protect blood vessels

Caffeine's anti-inflammatory effects may help protect blood vessels

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Autoimmune diseases more common in women who stop ovulating before 40

Autoimmune diseases more common in women who stop ovulating before 40

Over 80% of women are iron deficient by their third trimester

Over 80% of women are iron deficient by their third trimester

How viral persistence and immune dysfunction drive long COVID

How viral persistence and immune dysfunction drive long COVID

Premature ovarian insufficiency in women linked to greater risk of severe autoimmune conditions

Premature ovarian insufficiency in women linked to greater risk of severe autoimmune conditions

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Fever enhances immune cell activity and induces mitochondrial stress

Fever enhances immune cell activity and induces mitochondrial stress

Philanthropic investment establishes research center to advance precision diagnosis for diseases

Philanthropic investment establishes research center to advance precision diagnosis for diseases

Lupus Research Alliance announces 2024 Diversity in Lupus Research Award recipients

Lupus Research Alliance announces 2024 Diversity in Lupus Research Award recipients

New insight into the causes of autoimmune diseases

New insight into the causes of autoimmune diseases

Cancer drug offers life-changing results for severe lupus patient

Cancer drug offers life-changing results for severe lupus patient

New immune cell 'atlas' may aid in the diagnosis and treatment of children with life-threatening diseases

New immune cell 'atlas' may aid in the diagnosis and treatment of children with life-threatening diseases

Research unveils how hormones affect immune system differences between genders

Research unveils how hormones affect immune system differences between genders

New insights on how melanoma cells resist cancer immunotherapy

New insights on how melanoma cells resist cancer immunotherapy

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

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