Pharmacology News and Research

Latest Pharmacology News and Research

Micro-array technology is revolutionising current drug development

Gene expression micro-array technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics

29 Oct 2004

New insights into hormone therapy show when estrogen best aids brain

New hormone therapy studies demonstrate estrogen's ability to directly stimulate neurons, repair damaged neurons, and stimulate support cells—most of which can alleviate some of the cognitive decline associated with menopause.

28 Oct 2004

Smoking shown to quell painful sensations and heighten positive emotions

Smokers often say that lighting up a cigarette can calm their nerves, satisfy their craving and help them relax.

28 Oct 2004

Exercise protects brain cells affected by Parkinson's

In an animal model of Parkinson's, exercise prevents degeneration of nerve cells that are normally impaired or destroyed by the disease, according to University of Pittsburgh researchers.

24 Oct 2004

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Cyclopamine, derived from the corn lily may treat and prevent basal cell carcinoma

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have demonstrated in laboratory animals that a compound derived from a common plant can be used to treat and prevent the most widespread form of cancer in people

18 Oct 2004

New research points to potential new treatments for sickle cell disease

New research from the University of North Carolina at Chapel Hill reveals why red blood cells from people with sickle cell disease are stickier than healthy red cells, pointing the way to potential new treatments for sickle cell disease.

12 Oct 2004

Study raises important questions about the use of drugs that promote or prevent angiogenesis

Dartmouth Medical School cardiology researchers have discovered a new mechanism for what drives the growth of muscle tissue in the lining of injured heart vessels that can eventually lead to blockage.

11 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Stem cells and drug design

Victorian College of Pharmacy researchers hope stem cells will help them better understand the action of existing drugs and aid in the discovery of new drugs for illnesses such as depression, obesity and anxiety.

5 Oct 2004

Approval of Abilify (aripiprazole) for the treatment of acute bipolar mania

Bristol-Myers Squibb and Otsuka Pharmaceutical have announced that the U.S. Food and Drug Administration (FDA) has approved Abilify (aripiprazole) for the treatment of acute bipolar mania, including manic and mixed episodes associated with bipolar disorder.

4 Oct 2004

Should medical knowledge be extended to enhance the lives of those who are already healthy?

This question and others are addressed in three articles about cosmetic neurology in the September 28 issue of Neurology, the scientific journal of the American Academy of Neurology.

28 Sep 2004

Marijuana use may increase the risk of ectopic (tubal) pregnancies

It is not known whether drugs that block or, in the case of marijuana, over-stimulate the CB1 receptor can cause ectopic pregnancy in humans. However, "our results raise caution for women of reproductive ages regarding the chronic use of marijuana for recreation or pain alleviation," the researchers concluded.

27 Sep 2004

Arsenic could be toxic at much lower levels than previously thought

Arsenic could be toxic at much lower levels than previously thought, suggesting that the new EPA drinking water standard of 10 parts per billion might still be too high, according to a team of researchers at Dartmouth Medical School.

26 Sep 2004

Streptococcus bacteria uses sword and shield to fight white blood cells

A single gene called cylE within the important bacterial pathogen Group B Streptococcus (GBS), controls two factors that act together as a “sword” and “shield” to protect the bacteria from the killing effects of the immune system’s white blood cells

21 Sep 2004

New anti-inflammatory strategy for cancer therapy

A new strategy for cancer therapy, which converts the tumor-promoting effect of the immune system’s inflammatory response into a cancer-killing outcome, is suggested in research findings by investigators at the University of California, San Diego (UCSD) School of Medicine.

20 Sep 2004

Molecule that may be a primary cause of high blood pressure and link to diabetes

A study published in this week's Proceedings of the National Academy of Sciences identified the molecule that binds to a receptor (a molecule on the cell surface that triggers a reaction within the cell) in the brain that is known to regulate blood pressure and release of insulin.

14 Sep 2004

Researchers work to defeat acne by understanding it better on a molecular level

To defeat an enemy, you must first understand it, or so the saying goes. And for nearly every teenager and young adult, acne is a formidable foe, causing damage to their skin and their self-image that can leave long-lasting physical and emotional scars.

2 Sep 2004

Alcohol in moderation maintains a healthy heart and reduces tissue damage following a heart attack

For years researchers have tried to determine why the French have such a lower rate of cardiovascular disease, given the amount of fat consumed in their diets.

30 Aug 2004

Study of new gene and cell therapy to better understand how genetically-engineered cells can help pace the heart

Guidant Corporation, Columbia University and Stony Brook University will collaborate to study a new gene and cell therapy that may ultimately provide better understanding of how genetically-engineered cells can help pace the heart.

26 Aug 2004