Pharmacology News and Research

Latest Pharmacology News and Research

New drug combo shows promise in targeting RAS-mutant multiple myeloma

The combination of a drug and a protein fragment prevents the growth of blood cancer cells, a new study in mice shows.

11 Dec 2023

Study offers new hope for heart repair and regeneration with reduced mitochondrial activity

USF Health Heart Institute doctors are upbeat about cardiac regeneration. But when those batteries – heart muscle cells called cardiomyocytes − short circuit and die, the damage can be devastating.

8 Dec 2023

Vanderbilt's potential schizophrenia treatment enters phase 1 clinical trials

A potential schizophrenia treatment discovered through the Warren Center for Neuroscience Drug Discovery has been cleared by the U.S. Food and Drug Administration for use in phase 1 clinical trials-;the third WCNDD therapeutic to reach that benchmark.

7 Dec 2023

MedUni Vienna scientists discover new pain medication with fewer side effects

People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects.

6 Dec 2023

Research uncovers stealthy strategy of SARS-CoV-2 infection

Researchers have discovered a novel mechanism whereby the SARS-CoV-2 virus, which causes COVID-19, can vary its mode of infection in human cells. Published in the journal eLife, a team from the University of Minnesota and the Midwest Antiviral Drug Discovery (AViDD) Center found the virus can alternate between being highly infectious and avoiding detection by the immune system.

5 Dec 2023

Scientists uncover dopamine's role in learning from rewards and punishments

What happens in the human brain when we learn from positive and negative experiences? To help answer that question and better understand decision-making and human behavior, scientists are studying dopamine.

1 Dec 2023

Brain peptide identified as key player in heavy alcohol drinking

Alcohol is the most common addictive substance in the world. Every year in the U.S. excessive alcohol use costs $249 billion and causes approximately 88,000 deaths, as well as various chronic diseases and social issues.

1 Dec 2023

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Researchers at UC Davis Comprehensive Cancer Center have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice.

30 Nov 2023

Latest scientific findings provide new insights into heart and stroke health

More than 4,000 abstracts were presented during the American Heart Association's Scientific Sessions 2023 and Resuscitation Science Symposium 2023, held earlier this month in Philadelphia.

28 Nov 2023

Numbing agent lidocaine may have cancer-fighting properties

Lidocaine-;often used as numbing agent for outpatient medical procedures-;activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Nov 2023

MSU researchers discover why inflammation in the gut causes visceral pain

Researchers at Michigan State University may have discovered why visceral pain is so common in people who have experienced inflammation in their guts, including patients with irritable bowel syndrome, or IBS.

21 Nov 2023

Call for improved data sharing practices in the pharmaceutical industry

Development of potential or improved anti-cancer treatments are being blocked or slowed down by lack of transparency in data sharing between pharmaceutical companies and research groups, according to cancer clinicians, researchers and consumers.

21 Nov 2023

Study links nanoplastics to Parkinson's disease and dementia

Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson's disease and some types of dementia.

17 Nov 2023

New understanding of lung cancer cells' 'memories' suggests novel treatment approach

A new understanding of lung cancer cells' "memories" suggests a new strategy for improving treatment, Memorial Sloan Kettering Cancer Center (MSK) researchers have found.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Mediterranean diet linked to lower risk of cognitive decline in older adults

Old people who follow a Mediterranean diet are at a lower risk of cognitive decline, according to a study published in the journal Molecular Nutrition and Food Research.

17 Nov 2023

Hunger hormone directly impacts the brain to drive eating behavior

A hunger hormone produced in the gut can directly impact a decision-making part of the brain in order to drive an animal's behavior, finds a new study by UCL (University College London) researchers.

16 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Clinical trial underway for novel human milk-based microbiome therapy

In a breakthrough for human milk science, researchers at City of Hope, Los Angeles, have dosed the first patient in a Phase 2a clinical trial evaluating a novel therapy for blood cancer patients undergoing allogeneic hematopoietic stem cell transplantation.

10 Nov 2023

New report recommends mandatory prescribing exam for all UK doctors

The UK Prescribing Safety Assessment (PSA) is a ground-breaking medical exam with strong stakeholder support and is associated with increased confidence in prescribing and decreased reporting of medication-related patient harm. The

10 Nov 2023