Tuberous Sclerosis News and Research

Latest Tuberous Sclerosis News and Research

Study discourages use of non-standard therapies for infantile spasms

Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment with an effective therapy is important for improving neurodevelopmental outcomes and, for some children, can result in permanent remission of epilepsy.

28 Aug 2021

CBD may reduce the adverse effects of anti-seizure drugs in people with epilepsy

Artisanal (non-pharmaceutical) cannabidiol (CBD) products have become popular in recent years for their apparent therapeutic effects. CBD — a naturally occurring compound of the cannabis plant legally derived from hemp — is used widely as a naturopathic remedy for a number of health conditions, including epilepsy and seizure disorders.

11 Aug 2021

Study could help understand how Tuberous Sclerosis Complex arises

Tuberous Sclerosis Complex (TSC) affects between one and two of every 10,000 new-born babies. This genetic disease leads to the formation of benign tumors which can massively impair the proper functioning of vital organs such as the kidneys, the liver and the brain.

12 May 2021

Type 2 diabetes drug can successfully reduce symptoms associated with tuberous sclerosis complex

A team of researchers led by UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumors.

29 Mar 2021

FDA warns two companies for illegal marketing of unapproved CBD products

The U.S. Food and Drug Administration has issued warning letters to two companies for selling products labeled as containing cannabidiol (CBD) in ways that violate the Federal Food, Drug, and Cosmetic Act (FD&C Act).

22 Mar 2021

Study shows how genetic mutations lead to kidney cysts in tuberous sclerosis complex

Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin and kidneys. In about 80 percent of cases, it causes cysts and benign tumors to form in the kidney, eventually resulting in kidney failure.

5 Feb 2021

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the renowned journal Cell.

26 Jan 2021

Anchor proteins inhibit a key metabolic driver that plays critical role in cancer and neuronal diseases

Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders.

26 Jan 2021

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options.

8 Jan 2021

FDA issues warning letters to companies illegally selling unapproved CBD products

Today, the U.S. Food and Drug Administration issued five warning letters to companies for selling products containing cannabidiol (CBD) in ways that violate the Federal Food, Drug, and Cosmetic Act (FD&C Act).

22 Dec 2020

FDA approves CBD oral solution for treatment of seizures related to tuberous sclerosis complex

Today, the U.S. Food and Drug Administration approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with tuberous sclerosis complex (TSC) in patients one year of age and older.

31 Jul 2020

Study identifies brain circuitry that plays key role in ASD-relevant behaviors

A team led by UT Southwestern researchers has identified brain circuitry that plays a key role in the dysfunctional social, repetitive, and inflexible behavioral differences that characterize autism spectrum disorders (ASD).

15 Jul 2020

Clemson researcher receives DOD grant to explore cellular underpinnings of developmental disorder

College of Science associate professor and researcher David Feliciano has received a $667,000 grant from the Department of Defense to explore the cellular underpinnings of Tuberous Sclerosis Complex (TSC), a developmental disorder characterized by the growth of benign tumors throughout the body, most notably in the brain.

6 Jul 2020

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

24 Jun 2020

UM Medicine launches new centers in Maryland to treat adults with neurodevelopmental disabilities

The University of Maryland School of Medicine, University of Maryland Medical Center, and the Tuberous Sclerosis Alliance have joined together to launch first-of-a-kind centers in Maryland to treat adults with neurodevelopmental disabilities, such as autism.

8 Dec 2019

Tuberous Sclerosis News and Research

Latest Tuberous Sclerosis News and Research

Study discourages use of non-standard therapies for infantile spasms

CBD may reduce the adverse effects of anti-seizure drugs in people with epilepsy

Study could help understand how Tuberous Sclerosis Complex arises

Type 2 diabetes drug can successfully reduce symptoms associated with tuberous sclerosis complex

FDA warns two companies for illegal marketing of unapproved CBD products

Study shows how genetic mutations lead to kidney cysts in tuberous sclerosis complex

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

Anchor proteins inhibit a key metabolic driver that plays critical role in cancer and neuronal diseases

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

FDA issues warning letters to companies illegally selling unapproved CBD products

FDA approves CBD oral solution for treatment of seizures related to tuberous sclerosis complex

Study identifies brain circuitry that plays key role in ASD-relevant behaviors

Clemson researcher receives DOD grant to explore cellular underpinnings of developmental disorder

Cell signaling pathway may offer new drugs for tuberous sclerosis complex

UM Medicine launches new centers in Maryland to treat adults with neurodevelopmental disabilities

Study of 'face blindness' provides clues to what goes wrong in the brain

Findings could lead to potential new therapies for tumor-causing disorder

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

Gene mutation in the brain of autism patients alters behaviors in mice

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Tuberous Sclerosis News and Research

Latest Tuberous Sclerosis News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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