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Anal Cancer Risk Factors

HPV: Human papillomavirus examination of squamous cell carcinoma tumor tissues from patients in Denmark and Sweden showed a high proportion of anal cancers to be positive for the types of HPV that are also associated with high risk of cervical cancer (90% of the tumors from women, 100% of the tumors from homosexual men, and 58% of tumors from heterosexual men).

In another study done, high-risk types of HPV, notably HPV-16, were detected in 84 percent of anal cancer specimens examined.

Sexual activity: Having multiple sex partners due to the increased risk of exposure to the HPV virus. Receptive anal intercourse, whether male or female, increases the chances of anal cancer sevenfold.

Smoking: Current smokers are several times more likely to develop anal cancer compared with nonsmokers. hemorrhoids, fistulae or cicatrices).

Inflammation resulting from benign anal lesions, such as hemorrhoids and anal fistulas, has been considered to cause a predisposition to anal cancer.

Further Reading


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