Diagnosis of autoimmune disorders largely rests on accurate history and physical examination of the patient, and high index of suspicion against a backdrop of certain abnormalities in routine laboratory tests (example, elevated C-reactive protein). In several systemic disorders, serological assays which can detect specific autoantibodies can be employed. Localised disorders are best diagnosed by immunofluorescence of biopsy specimens.
Treatments for autoimmune disease have traditionally been immunosuppressive, anti-inflammatory, or palliative.
T cell vaccination is also being explored as a possible future therapy for auto-immune disorders.
Further Reading
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