A hemangioma of infancy (or haemangioma of infancy) is a benign self-involuting tumor of endothelial cells (the cells that line blood vessels). In most cases it appears during the first days or weeks of life and will have resolved at the latest by age 10. In infancy, it is the most common tumor.
Before considering the hemangioma, it is important to understand that
there have been changes in the terminology used to define, describe and
categorize vascular anomalies (abnormal lumps made up of blood vessels).
The term ''hemangioma'' was originally used to describe any vascular
tumor-like structure, whether it was present at or around birth or
appeared later in life. Mulliken et al. categorized these conditions
into two families; a family of self-involuting tumors (growing lesions
that eventually disappear) and another family of malformations (enlarged
or abnormal vessels present at birth and essentially permanent).
The
importance of this distinction is that it makes it possible for
early-in-life differentiation between lesions that will resolve versus
those that are permanent.
Examples of permanent malformations include
Port-wine stains (capillary vascular malformation) and masses of
abnormal swollen veins (venous malformations). Unfortunately many
textbooks and dictionaries are not up to date, creating great confusion.
Hemangiomas go through three stages of development and
decay:
- In the proliferation stage, a hemangioma
grows very quickly. This stage can last up to twelve months.
- In the rest stage, there is very little
change in a hemangioma's appearance. This usually lasts until the infant
is one to two years old.
- In the involution phase, a hemangioma
finally begins to diminish in size. Fifty percent of lesions will have
disappeared by age five with the vast majority gone by 10 years of age.
Further Reading
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"Hemangioma"
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