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Prokaryotic DNA Polymerases

Bacteria have 5 known DNA polymerases:

  • Pol I: implicated in DNA repair; has 5'->3' (Polymerase) activity and both 3'->5' exonuclease (Proofreading) and 5'->3' exonuclease activity (RNA Primer removal).
  • Pol II: involved in reparation of damaged DNA; has 3'->5' exonuclease activity.
  • Pol III: the main polymerase in bacteria (elongates in DNA replication); has 3'->5' exonuclease proofreading ability.
  • Pol IV: a Y-family DNA polymerase.
  • Pol V: a Y-family DNA polymerase; participates in bypassing DNA damage.

Further Reading


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