Improved blood pressure control of people 80 years and older, especially women, must be made a national priority, a
Northwestern University researcher urged at the American Society of Hypertension’s 19th Annual Scientific Meeting in May.
“The current rates of blood pressure control in the elderly are unacceptably low,” said Donald M. Lloyd-Jones, M.D., assistant professor of preventive medicine and assistant professor of medicine, division of cardiology, at Northwestern University Feinberg School of Medicine.
Lloyd-Jones said that among hypertensive individuals in the 1990s, the overall prevalence of blood pressure control (lower than 140 systolic/90 diastolic) was around 34 percent. Control rates declined with advancing age, with a more dramatic decline in women. Among those 80 and older with hypertension, only 32 percent of men and 24 percent of women had their blood pressure under control.
“The elderly are the fastest-growing segment of the U.S. population, and they have the highest prevalence of hypertension. Yet, clinicians seem to be reluctant to treat older patients aggressively, perhaps because of perceived lower benefits or possible increased risk of side effects,” Lloyd-Jones said.
Lloyd-Jones and colleagues from the National Heart, Lung, and Blood Institute’s Framingham Heart Study pooled data from almost 14,100 examinations of participants in the study from 1990 through 1999.
The Framingham Heart Study, initiated in 1948 in Framingham, Mass., is the longest-running prospective epidemiological study of heart disease. Researchers are now enrolling the grandchildren of the study’s original participants.
The current study included about 2,230 men and 2,960 women. Participants were classified by age – younger than 60, 60 to 79 and 80 and older.
As expected, the prevalence of hypertension increased markedly with advancing age. In the younger-than-60 age group, around 27 percent had high blood pressure; and in the 60-to-79 age group, about 59 percent had high blood pressure. In the group aged 80 and older, over 70 percent had high blood pressure.
The overall prevalence of treatment was around 66 percent. Treatment rates increased substantially from the younger -to-old age group (57 percent to 72 percent), with no further increase in the “old-old,” 80-and-over group (73 percent).
However, the number of antihypertensive medications used was similar across all age groups, with two thirds of treated hypertensive patients using only one medication; 25 percent using two medications; and fewer than 10 percent using three medications, Lloyd-Jones said.
Lloyd-Jones noted that the use of thiazide diuretics increased steadily with advancing age, but remained suboptimal.
In the 80-and-older group, only 22 percent of men and 32 percent of women with hypertension were using thiazide diuretics for therapy, despite the fact that thiazides have been shown to be extremely effective in older hypertensive patients.