AMDL, Inc. has announced that it has received an important Israeli patent for an animal model for the evaluation of vaccines, which is a part of its unique Combination Immune Therapy (CIT) technology.
CIT is a technology owned by AMDL that may be useful in treating specific forms of cancer.
AMDL also has patents and patents pending claiming a novel model, and methods of using these models, derived through the CIT technology it believes will be far more useful than animal studies because AMDL's "humanized" mice have human-like immune systems. "Medical science has long been concerned about adverse occurrences in human trials that aren't predicted in traditional animal studies," said Gary Dreher, AMDL CEO. "With the novel animal models we have developed, some of these important concerns could be eliminated."
The "humanized" mouse as claimed by AMDL has been engineered to possess a human-like immune system. This "transgenic" mouse is extremely useful for studying the potential therapeutic benefits of candidate gene therapy compositions. Because the natural mouse immune system differs from the human immune system, experiments conducted in conventional mice are not always predictive of how new therapeutic compounds will work in humans. However, transgenic mice made in accordance with AMDL's patents have an immune system more like a human's. Results obtained from experiments using this mouse may correlate significantly better than traditional animal models. That is why these mice are referred to as "humanized mice."