More than 250 million women worldwide smoke tobacco. Compared to men, women have a greater risk of smoking-related diseases, and also have more difficulty quitting. A new study, the first of its kind, has found that cigarette smoking and having a family history of alcoholism have different effects on sweet-taste perception and food cravings.
Results are published in the November issue of Alcoholism: Clinical & Experimental Research.
“Tobacco is one of the most heavily used addictive drugs,” said M. Yanina Pepino, a researcher at the Monell Chemical Senses Center in Philadelphia and corresponding author for the study, “leading to an increased risk of lung and heart diseases and a variety of cancers.” In fact, lung cancer has surpassed breast cancer as the leading cause of death among US women, she added.
“Women who smoke also have an increased risk of cervical cancer, reproductive and pregnancy complications, and early menopause,” said Pepino. “Compared to men, women are also more sensitive to some of the harmful effects of smoking: lung disease progresses more quickly in women, and they are at a greater risk for coronary heart disease, especially if they smoke while using oral contraceptives.”
Despite the greater health risks, women derive more pleasure than men from the smell and taste of cigarettes, are more likely to smoke as a way to reduce stress and feelings of depression, and use smoking as a diet tool. In fact, said Pepino, many women who try to quit smoking often relapse because of concerns about gaining weight.
At the same time, said Alexei B. Kampov-Polevoy, research assistant professor of psychiatry at The University of North Carolina at Chapel Hill, sweet taste is one of the first pleasures we experience, for example, mother's milk. “There is growing evidence that our hedonic response to sweet taste reflects integrative activity of the brain-reward system, specifically, of the brain opioid system,” he said. “Distortions of perception of sweet taste and craving for sweets have been reported in patients with various psychiatric conditions – depression, substance abuse, eating disorders, premenstrual syndrome, several forms of obesity etc. Considering that hedonic response to sweet taste is at least in part regulated by genetic mechanisms, and that differences in response can be detected at birth, this trait may be a potential marker of the risk for many psychiatric conditions.”
For this study, researchers examined two groups of women between 21 and 40 years of age: 27 current smokers (18 had a positive family history of alcoholism), and 22 women who had never smoked in their lives (9 had a positive family history of alcoholism). Each woman was tested on two days separated by one week. Cravings for specific foods and, for the smokers, cravings for cigarettes, were measured. Smokers were given nicotine-containing cigarettes during one test session, and nicotine-free cigarettes during the other. Thirty minutes after smoking for smokers, and 30 minutes after arrival for nonsmokers, study authors assessed sucrose thresholds and preferences during both test sessions.