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Need for greater recognition of the use of placebos

Published on January 4, 2008 at 2:54 AM · No Comments

In the first study examining American physicians' use of placebos in clinical practice in the 21st Century, 45 percent of Chicago internists report they have used a placebo at some time during their clinical practice researchers report in the January issue of Journal of General Internal Medicine.

This study indicates a need for greater recognition of the use of placebos and unproven therapies and discussion about its implications," say the study authors, Rachel Sherman, a fourth year medical student at the University of Chicago's Pritzker School of Medicine, and John Hickner, MD, MSc, professor of family medicine, at the University of Chicago and University of Chicago Medical Center.

The authors sent questionnaires inquiring about placebo use to 466 internists at the University of Chicago, Northwestern University, and University of Illinois – Chicago. Fifty percent (231) of the physicians responded.

"Placebos have been used in medicine since ancient times, and remain both clinically relevant and philosophically interesting. In addition to their recognized use as controls in clinical trials, this study suggests that placebos themselves are viewed as therapeutic tools in medical practice," says Sherman.

Of the respondents who reported using placebos in clinical practice, 34 percent introduced the placebos to the patient as "a substance that may help and will not hurt." Nineteen percent said, "it is medication," and nine percent said, "it is medicine with no specific effect." Only four percent of the physicians explicitly said, "it is a placebo." In addition, 33 percent of the physicians reported they gave other information to patients, including, "this may help you but I am not sure how it works."

Only 12 percent of respondents said that placebo use should be categorically prohibited. The authors write that in the broader ethics literature, the routine use of placebos is controversial. Some commentators on informed consent and non-deceptive therapeutics caution against the use of placebos in medical practice. Others propose that the placebo effect can be harnessed in various therapeutic contexts that do not pose ethical dilemmas.

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