Patients with moderate COPD were randomized to receive "usual care" or to undergo an interdisciplinary, community-based program (INTERCOM) that offered an intensive lifestyle moderation phase of four months, during which patients were instructed in detail to perform two 15-minute intervals of pleasurable walking or cycling, and offered instruction in other lifestyle changes such as nutrition and smoking cessation.
After the four-month introductory period, there was a less intensive 20-month maintenance during which patients were offered guidance but not intensive intervention.
Researcher Carel van Wetering, from the Department of Respiratory Medicine at the Maxima Medical Centre and colleagues randomized patients with mild to moderate COPD to receive "usual care" or undergo an interdisciplinary, community-based program (INTERCOM) that offered an intensive lifestyle moderation phase of four months, during which patients were instructed in detail to perform two 15-minute intervals of pleasurable walking or cycling, and offered instruction in other lifestyle changes such as nutrition and smoking cessation. After the four-month introductory period, there was a less 20-month maintenance period.
The study results will be presented at the 105th international conference of the American Thoracic Society, taking place in San Diego from May 15-20.
After two years, the researchers found that, compared with patients who had gotten the usual care, those who had undergone the INTERCOM program showed significant improvements in health status (SGRQ); exercise capacity, and dyspnea. Improvements were seen at four months with respect to disease-specific quality of life, walk distance, exercise capacity, dyspnea, handgrip force and fat free mass index. After two years improvements in exercise capacity remained significant, as were improvements over the entire period in dyspnea (MRC) and disease-specific quality of life.
Furthermore, perceived effectiveness - the patients' subjective evaluation of the benefits of the program highly favored the INTERCOM program.