<< More than half of women with ovarian cancer face delay in diagnosis | Stony Brook University Hospital and EPA sign historic green partnership >>
Read in | English | Français | Português | Nederlands | Filipino

Cannabis chemicals halt prostate cancer growth

Published on August 26, 2009 at 4:53 PM · 1 Comment

Active chemicals in cannabis have been shown to halt prostate cancer cell growth according to research published in the British Journal of Cancer.

Researchers from the University of Alcala, in Madrid tested the effects of the active chemicals in cannabis called cannabinoids on three human prostate cancer cell lines - called PC-3, DU-a45 and LNCaP.

The prostate cancer cells carry molecular "garages"" called receptors - in which cannabinoids can 'park'.

The scientists showed for the first time that if cannabinoids "park" on a receptor called CB2, the cancer cells stop multipyling.

But Dr Lesley Walker, Cancer Research UK's director of cancer information warned patients against smoking the drug. She said: "This is interesting research which opens a new avenue to explore potential drug targets but it is at a very early stage - it absolutely isn't the case that men might be able to fight prostate cancer by smoking cannabis."

Dr Walker added: "This research suggest that prostate cancer cells might stop growing if they are treated with chemicals found in cannabis but more work needs to be done to explore the potential of the cannabinoids in treatment."

To confirm the findings the scientists switched off the CB2 receptors - or 'closed the garage doors'- on the prostate cells. When cannabinoids were then added to cells without the CB2 receptor, the prostate cancer cells carried on dividing and growing. This suggests that cannabinoids connect with the CB2 receptors on prostate cancer cells to stop cell division and spread.

Comments
  1. anonymous anonymous United States says:

    I find it maddening that the United States govt refuses to allow people to conduct important research like this because of personal agendas and racist-based laws from long ago.

    The UK has also done cutting-edge research on cannabinoids inhibiting growth of MRSA bacteria.  I personally know someone who almost died from MRSA bacteria getting loose in his system and want to see more research allowed and funded.

    Maybe what it will take is people filing lawsuits against governmental bodies such as the U.S.-based DEA based on wrongful deaths to allow more people to conduct this sort of research without fear of being imprisoned.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.



  Country flag

biuquote
  • Comment
  • Preview
Loading