In an effort to provide breast cancer patients with prompt, critical information about treatment options for use at their first visit with the medical oncologist, a number of leading U.S. surgeons request Genomic Health's Oncotype DX molecular test at the time of surgery or biopsy.
Oncotype DX is a multigene expression test that analyzes the activity of 21 genes within a breast cancer patient's tumor to calculate an individualized result known as a Recurrence Score®. Additionally, the test report provides quantitative scores for certain individual genes. As of May 2009, physicians have used Oncotype DX for breast cancer treatment planning in more than 100,000 patients in over 40 countries worldwide. It is the only validated multigene expression test recommended in the treatment guidelines issued by both the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN).
"Obtaining these findings early on helps reduce a patient's anxiety about treatment and helps us ensure adherence to established quality-of-care indicators," says Harry D. Bear, MD, PhD, chairman, Division of Surgical Oncology and professor of Surgery and Microbiology & Immunology at the Virginia Commonwealth University School of Medicine & VCU Massey Cancer Center in Richmond.
Dr. Bear served as chair and moderator for the monograph entitled, "Oncotype DX Assay for Breast Cancer" in the August 2009 issue of Contemporary Surgery. The recommendations are based on his experience as a surgical oncologist and that of three other physicians from leading U.S. cancer centers.