Cardium Therapeutics (NYSE Amex: CXM) today reported on preclinical findings published in the scientific journal, Gene Therapy, demonstrating that Cardium's Gene Activated Matrix(TM) or GAM(TM) technology accelerates periodontal tissue regeneration of oral implant-supporting wounds. The PDGF-B gene therapy accelerates bone engineering and oral implant osseointegration study (Chang, et al., Gene Therapy; 10 September 2009; doi: 10.1038/gt.2009.117) conducted by researchers at the University of Michigan is available online at nature.com/doifinder/10.1038/gt.2009.117, and reports on the use of AdPDGF-B/collagen (the key component of the Company's Excellarate(TM) product candidate) to promote oral implant osseointegration. The study's findings demonstrate that AdPDGF-B/collagen is safe, accelerates and enhances oral implant osseointegration, and leads to significantly higher bone-implant contact, defect fill, bone area and tissue mineral density than placebo.