GlobeImmune to present an abstract of GI-5005 drug at AASLD's annual meeting

GlobeImmune Inc. today announced that a late breaking abstract related to GI-5005, its investigational hepatitis C virus (HCV) product candidate, has been accepted for presentation at the 60th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), which will take place Oct. 31 through Nov. 4, 2009, in Boston, Mass.

The abstract, titled "GI-5005 Therapeutic Vaccine Plus PEG-IFN/Ribavirin Improves End of Treatment Response at 48 Weeks Versus PEG-IFN/Ribavirin in Naïve Genotype 1 Chronic HCV Patients," is published online at the AASLD website (www.aasld.org).

At the AASLD meeting, GlobeImmune will present end-of-treatment, 48-week data in interferon-naïve patients from a Phase 2 clinical study investigating the efficacy and safety of GI-5005 plus peg-interferon (peg-IFN) and ribavirin, the current standard of care (SOC), in patients with genotype 1 chronic HCV infection compared to patients receiving only SOC.

Dr. John G. McHutchison, associate director of the Duke Clinical Research Institute at Duke University Medical Center, is the lead author of the abstract that will be presented as part of a late breaking poster session beginning at 8 a.m. EST on Monday, Nov. 2, 2009. The presentation will include complete response rates and ALT data for patients who completed 48 weeks of triple therapy, as well as SOC patients in the control arm of the study.

GI-5005 is a therapeutic vaccine product candidate that contains conserved HCV proteins and is designed to generate HCV specific T-cell responses in both the pre-clinical and clinical setting.