The UK National Health Service could save millions of pounds a year by routinely using inexpensive dressings to treat venous leg ulcers, after a study published in the October issue of BJS showed that they are just as effective as expensive silver dressings in the majority of cases.
Researchers, led by Professor Jonathan Michaels from the Sheffield Vascular Institute and Professor Bruce Campbell from the Royal Devon and Exeter Hospital, studied 213 leg ulcer patients who received either standard low-adhesive dressings or antimicrobial silver-donating dressings.
There were no significant differences between the two groups when it came to healing rates and quality of life, but the silver dressings were significantly more expensive.
Median healing time for the group treated with silver dressings was 67 days, with 59.6 per cent healing by 12 weeks, compared to 58 days and 56.7 per cent for the control group. By six months, 85 per cent of the silver dressing group and 77 per cent of the control group had a healed ulcer and by one year the figures were 96 per cent for both groups.
But the average cost of treating a patient with silver dressings was £417.97, including staff time and materials, more than 30 per cent higher than the £320.12 for the control group.
"Latest figures from the National Prescribing Centre suggest that wound dressings cost the NHS £100 million in 2006-7, excluding staff time, and that silver dressings accounted for a quarter of this cost" says Professor Michaels.
"However, until now, no studies have been published examining the cost-effectiveness of using antimicrobial silver-donating dressings beneath compression therapy to treat venous leg ulcers."
Venous leg ulcers are relatively common in older people and, as the population ages, the costs of caring for them increases. They occur when blood pressure in the veins of the lower leg causes fluid to ooze out of the veins beneath the skin. This causes swelling and thickening and the damaged skin may eventually break down to form an ulcer.
Multilayer compression bandaging is now the standard treatment for venous leg ulcers, with dressings placed over the actual wound to promote healing.
"A great variety of different dressings are used, but quality evidence for the benefits of specific dressings is sparse and systematic reviews have shown no statistically significant difference in the number of ulcers healed between any of the dressing types" says Professor Michaels.
"The use of antimicrobial dressings has become widespread, particularly for venous ulcers, based on an anticipated advantage over simple dressings. As venous ulcers are common, and antimicrobial dressings are relatively expensive, their use has potentially large consequences for health services."
The VULCAN study, funded by the NIHR Health Technology Assessment programme, was carried out over a two-and-a-half year period on patients who had had active ulceration of their lower leg for more than six weeks. Patients were recruited from South Yorkshire and Devon, mainly from primary care clinics specialising in leg ulcers.