Using just 1 popular test or the other could miss serious cardiac abnormalities
To best detect early signs of life-threatening heart defects in young athletes, screening programs should include both popular diagnostic tests, not just one of them, according to new research from heart experts at Johns Hopkins.
Sudden cardiac death due to heart rhythm disturbances is blamed for more than 3,000 deaths a year in young people, especially athletes who have inherited tendencies to develop overly enlarged and thickened hearts, says Theodore Abraham, M.D., an associate professor at the Johns Hopkins University School of Medicine and its Heart and Vascular Institute. In some instances, top athletes have died from heart conditions while seemingly in peak physical form, something that can hide warning signs and allow many cases to go undiagnosed.
In a study to be presented Nov. 15 at the American Heart Association's (AHA) annual Scientific Sessions in Orlando, Abraham and colleagues analyzed data from 134 top Maryland high school athletes that they screened at the 2008 track and field state championships. The researchers were looking for life-threatening cardiac abnormalities, such as hypertrophic cardiomyopathies. Doctors took a medical history, took weight and blood pressure measurements and listened for unusual heartbeats or murmurs. They also conducted an echocardiogram - a cardiac ultrasound, or ECHO - to measure heart size and pumping function and to check for faulty heart valves; and an electrocardiogram, or EKG, to assess the heart's electrical rhythms.
None of the student athletes were found to have life-threatening heart defects, but abnormal findings were discovered in 36 athletes. Twenty-two of those abnormalities were found by EKG alone, nine by ECHO alone and five were picked up on both tests. Those with abnormalities -- which included 19 with high blood pressure, 29 with elevated blood pressure in need of future monitoring, and five with low blood pressure readings -- were referred for follow-up to their doctors.
"If you are going to screen, it has to be comprehensive," says Abraham, who spearheads the annual "Heart Hype" screening program run by Johns Hopkins, and designed to serve as a national model for other leading academic medical centers. Some screening programs just include EKGs and not ECHOs. "An EKG does show you a lot," he says, "but it doesn't tell you the whole story. The advantage of a comprehensive screening is that it is holistic, rather than being pinpoint."
For example, if a doctor were screening for prostate cancer, "he wouldn't ignore a large tumor on your head," Abraham says.
Lead study investigator Aurelio Pinheiro, M.D., a postdoctoral research fellow at Hopkins, says he wasn't surprised that he and his colleagues didn't find anyone with a life-threatening heart abnormality since it is estimated that one in 500 Americans has undiagnosed hypertrophic cardiomyopathy and the Hopkins team screened fewer than that. Still, he says, the screening program is not just designed to prevent deaths from sudden cardiac arrest, but also to raise awareness of the risks to young athletes.