Proteostasis Therapeutics announced today that it has entered into an
exclusive license agreement with New York University for intellectual
property related to discoveries from the laboratory of David Ron, M.D.,
Professor of Medicine and Julius Raynes Professor of Cell Biology at NYU
Langone Medical Center’s Skirball Institute of Biomolecular Medicine.
Dr. Ron’s research focuses on the Unfolded Protein Response (UPR) and
his laboratory identifies new components of the cellular response to
stress, which is the mechanism behind many common diseases of aging. The
UPR is an important part of the Proteostasis Network (PN), the cellular
machinery that maintains protein health. The exclusive license
accelerates the Company’s drug discovery efforts to identify
Proteostasis Regulators (PRs), small molecule drugs designed to restore
protein balance. In addition, Dr. Ron has joined the Company’s
Scientific Advisory Board.
“Our lab is focused on uncovering new components of the cellular stress
response and understanding their role in the pathology of human
diseases”