The U.S. government's request that the journals Science and Nature withhold scientific information related to the genetically modified H5N1 virus because of biosecurity concerns does not violate the First Amendment, say two Georgetown University professors. They caution, however, that a fair, transparent process undertaken by research organizations is preferable to governmental constraints on disseminating scientific information.
Writing in Science, John D. Kraemer, JD, MPH, assistant professor of health systems administration at Georgetown University School of Nursing & Health Studies, and Lawrence O. Gostin, the Linda D. and Timothy J. O'Neill Professor of Global Health Law and faculty director of the O'Neill Institute for National and Global Health Law at Georgetown University Law Center, explore the balance of scientific freedom and national security in their opinion piece published online today entitled, "The Limits of Government Regulation of Science."
In 2011, two research teams genetically modified the H5N1 avian influenza virus. Their work, funded by the National Institutes of Health (NIH), demonstrates the ability to alter a virus in such a way that it could possibly spread rapidly among humans - killing more than half who contract it (the research was conducted in an animal model believed to represent human behavior of the virus). The research prompted the National Science Advisory Board for Biosecurity (NSABB), which advises the Department of Health and Human Services (HHS), to recommend that Science and Nature redact key information prior to publication. Both NSABB and HHS expressed concerns that published details about the papers' methodology and results could become a blueprint for bioterrorism.
"The NSABB process seems to have worked well in this instance," says Kraemer. "It raised legitimate security concerns while avoiding censorship of the scientific press. But there remains a need to strengthen precautions around this type of research before it occurs."
To date, Science and Nature have not yet announced their intentions regarding the government's request.
In their commentary, Kraemer and Gostin write "HHS' request reveals a troubled relationship between security and science." However, the authors point out, "Given the absence of legal force or undue inducements or penalties, the government's request to withhold information does not violate the First Amendment."
Kraemer and Gostin say the First Amendment, "affords considerable protection to political artistic and scientific expression, triggering 'strict scrutiny' by the Supreme Court." They point out that had the government compelled either the researchers or the journals to withhold publication, that act would have violated the First Amendment.
In their opinion piece, the authors explore various court cases that challenge and support the government's rights to go further with such an issue. They say the federal government has the power to prevent dissemination of sensitive life science research, but warn, "- there are good reasons to exercise that power sparingly."
Looking beyond the current dilemma, Kraemer and Gostin ask: "Can the review process for high-risk biologic research be improved further?"