A new multicenter study published in The Open Pain Journal (2012, 5, 32-37) showed that daily consumption of the pentose carbohydrate D-ribose (Corvalen™: 5 grams, 3 times a day over 3 weeks) resulted in an average energy boost of 61 percent among patients diagnosed with Chronic Fatigue Syndrome (CFS) and fibromyalgia (FMS). In addition, sleep, pain, mental clarity and overall well-being improved. The study, headed by board certified internist Jacob Teitelbaum, MD, involved 257 people with (CFS) and FMS from 53 different health clinics.
The research showed that consuming D-ribose led to both statistically (p<.0001) and clinically highly significant average improvements in all categories:
- 61.3 % increase in energy
- 37% increase in overall well-being
- 29.3% improvement in sleep
- 30% improvement in mental clarity
- 15.6% decrease in pain
These findings confirmed results of an earlier pilot study published in the Journal of Alternative and Complementary Medicine (2006:12 (9):857-862), involving 36 patients from a single medical center, who took D-ribose for an average of 25 days. Approximately 66% of patients experienced significant improvement while on D-ribose, with an average increase in energy of 45% and an average improvement in overall well-being of 30% (p<.0001).
The purpose of the new study was to reconfirm the efficacy of D-ribose for improving the quality of life in energy-depleted patients diagnosed with fibromyalgia (FMS) and/or CFS, and to see if the results could be generalized to the CFS and FMS community as a whole.