ConservoCare, LLC, a spinoff of research at Case Western Reserve University, has obtained license options through the university's Technology Transfer Office to develop a medical device for bladder control.
ConservoCare, based in Atlanta, is focused on restoring bladder function lost due to injury or illness. Patients with spinal cord injuries who experience urethral sphincter spasms are likely to be the first to benefit from the device, which uses electrical nerve stimulation to control the bladder.
"Along with providing world-class research in many areas, Case Western Reserve University is striving to translate these exciting discoveries, putting them into the marketplace," said Jeffrey Duerk, dean of the university's Case School of Engineering. "We encourage our faculty to conduct basic research, but also to provide innovative solutions to a wide variety of issues and clinical needs."
Kenneth Gustafson, PhD, associate professor of biomedical engineering and urology and a research scientist at Louis Stokes Cleveland VA Medical Center, is working closely with ConservoCare on feasibility of a nerve-block medical device.
"ConservoCare is taking this technology to the next step by translating what is learned in the laboratory and implementing it in the clinical setting," Gustafson said. His laboratory develops neural prostheses to restore pelvic functions. These "pacemakers for the bladder" are being tested in pre-clinical and clinical studies.
ConservoCare's device uses high-frequency electrical nerve stimulation to eliminate sphincter spasms and allow on-demand control of bladder function. Implanting a nerve cuff electrode for feasibility testing requires approval from the U.S. Food and Drug Administration (FDA). The company also hopes to receive FDA approval to commercialize the device within five years.
Researchers expect to market the device to spinal cord injury patients and others suffering from urinary retention or incontinence. Without a safe and reliable way to control the bladder, these patients run a risk of urinary tract infections and kidney damage.