Study exposes widespread inaccuracies in cannabidiol product labeling

Scientists at the North-West University, South Africa, have recently tested the cannabidiol content of many commercial products and found discrepancies between the actual amount and the claimed amount of cannabidiol present in these products.

The study is published in the journal Phytomedicine Plus.

Study: Cure-all Cannabidiol? The cannabidiol content of commercial products. Image Credit: 24K-Production / ShutterstockStudy: Cure-all Cannabidiol? The cannabidiol content of commercial products. Image Credit: 24K-Production / Shutterstock

Background

Cannabidiol is the second most active compound found in cannabis plants. With the recent relaxation in cannabis use law, a sharp increase in commercial products containing cannabidiol has been observed worldwide. Many cannabidiol-containing products that do not include Δ9-tetrahydrocannabinol (the main psychoactive compound in cannabis) are now available in the market mainly as cure-all medications.

One major problem associated with cannabidiol-containing products is the misleading and false claims made by the manufacturers regarding the health benefits of these products. Such misleading health claims can potentially put consumers at risk of developing serious health complications because of not getting the actual medication or treatment they need.

Recent evidence indicates that many cannabidiol-containing products also contain Δ9-tetrahydrocannabinol above the legal limit. Moreover, inaccuracies in cannabidiol content have been noticed in some products. These observations indicate the lack of proper quality control measures in marketed cannabidiol products.

In this study, scientists have tested the cannabidiol content in commercially available products in South Africa to examine the accuracy of product label claims. They have also investigated whether these products contain Δ9-tetrahydrocannabinol.

Study design

A total of 40 commercially available products were quantitatively analyzed in the study to determine the concentration of cannabinoids. The products that included oils, drinks, topicals, and other categories were selected based on the label claims of cannabidiol content.

The high-performance liquid chromatography (HPLC) method was used to analyze the products and determine cannabinoid concentration. The labeling accuracy of the products was determined by the United States Pharmacopeia products purity guidance, which sets the acceptable range for the product labeling as ± 10%. The products were classified as over-labeled <90%, under-labeled >110%, and correctly labeled 90 – 110%.   

Important observations

Cannabidiol-containing oils

A total of 16 oil products were tested in this study. The product with the highest claimed cannabidiol content was found to have 98% less cannabidiol than the claimed concentration. Another product from the same manufacturer, labeled as "essential CBD oil blends," failed to show detectable levels of cannabidiol when measured.

Only 3 out of 16 products in this category were correctly labeled. Over-labeling and under-labeling were observed in eight products and one product, respectively. Notably, the products that did not mention cannabidiol concentration in the labels were found to have no detectable amount of cannabidiol.

Cannabidiol-containing topicals

A total of five topicals were analyzed in this study. A face mask product claiming "anti-aging ingredients" was found to have 98% less cannabidiol than the concentration mentioned on the label. Another product with a label claim of 10,000 mg cannabidiol hemp oil content failed to reach any detectable level of cannabidiol when measured.

A product marketed as a CBD lip balm with no mention of cannabidiol concentration on the label also failed to show detectable levels of cannabidiol.

Cannabidiol-containing drinks 

A total of 12 drinks were tested in this study. None of the products in this category were correctly labeled. All products were over-labeled. However, the analysis revealed that the products have considerably lower cannabidiol content than the claimed concentrations.

All these products were water-based. A low solubility of cannabidiol in water could be the reason behind the lower cannabidiol concentrations detected in these products.

Besides these three categories, cannabidiol-containing coffee, honey, capsules, gummy bears, and sachets were tested in this study. The majority of these products were over-labeled. However, the analysis revealed that these products either have undetected cannabidiol content or a lower-than-claimed concentration of cannabidiol.

Presence of Δ9-tetrahydrocannabinol

Of all tested products, 12 were correctly labeled regarding their Δ9-tetrahydrocannabinol content. One product that claimed to contain only cannabidiol was found to have trace amounts of Δ9-tetrahydrocannabinol.

Study significance

The study finds that a significant proportion of cannabidiol-containing products in South Africa have misleading information about concentrations and chemical properties of cannabidiol in their labels. This information indicates a significant lapse in quality control measures.

Overall, the study highlights that a wide range of health benefits claimed by these products do not actually have any fundamental basis.  

Journal reference:
Dr. Sanchari Sinha Dutta

Written by

Dr. Sanchari Sinha Dutta

Dr. Sanchari Sinha Dutta is a science communicator who believes in spreading the power of science in every corner of the world. She has a Bachelor of Science (B.Sc.) degree and a Master's of Science (M.Sc.) in biology and human physiology. Following her Master's degree, Sanchari went on to study a Ph.D. in human physiology. She has authored more than 10 original research articles, all of which have been published in world renowned international journals.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Dutta, Sanchari Sinha Dutta. (2023, November 30). Study exposes widespread inaccuracies in cannabidiol product labeling. News-Medical. Retrieved on October 31, 2024 from https://www.news-medical.net/news/20231130/Study-exposes-widespread-inaccuracies-in-cannabidiol-product-labeling.aspx.

  • MLA

    Dutta, Sanchari Sinha Dutta. "Study exposes widespread inaccuracies in cannabidiol product labeling". News-Medical. 31 October 2024. <https://www.news-medical.net/news/20231130/Study-exposes-widespread-inaccuracies-in-cannabidiol-product-labeling.aspx>.

  • Chicago

    Dutta, Sanchari Sinha Dutta. "Study exposes widespread inaccuracies in cannabidiol product labeling". News-Medical. https://www.news-medical.net/news/20231130/Study-exposes-widespread-inaccuracies-in-cannabidiol-product-labeling.aspx. (accessed October 31, 2024).

  • Harvard

    Dutta, Sanchari Sinha Dutta. 2023. Study exposes widespread inaccuracies in cannabidiol product labeling. News-Medical, viewed 31 October 2024, https://www.news-medical.net/news/20231130/Study-exposes-widespread-inaccuracies-in-cannabidiol-product-labeling.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Study reveals slight increase in ADHD risk from prenatal cannabis exposure