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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists find seven new genes that can cause X-linked intellectual disability

X-linked intellectual disability is a disorder that predominantly affects men and can have highly variable clinical manifestations. Scientists at the Max Planck Institute for Molecular Genetics in Berlin have found seven new genes that can cause this genetic disease: Mutations of these genes on the X chromosome lead to various forms of intellectual disability.

15 Feb 2015

UT Southwestern researchers identify common signaling mechanism that controls immune system

UT Southwestern Medical Center researchers have identified a common signaling mechanism to produce interferon - one of the main proteins used to signal the immune system when the body needs to defend itself against a virus, tumor, or other diseases.

15 Feb 2015

A*STAR's GIS scientists develop new system that can predict treatment targets for cancer

In recent months, several national initiatives for personalized medicine have been announced, including the recently launched precision medicine initiative in the US, driven by rapid advances in genomic technologies and with the promise of cheaper and better healthcare. Significant challenges remain, however, in the management and analysis of genetic information and their integration with patient data.

15 Feb 2015

New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

Scientists from NTU Singapore, the world's No. 1 young university, have developed an antibody which boosts the survival chances for patients suffering from influenza and pneumonia.

14 Feb 2015

$Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC$

Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC

Eisai Inc. announced today that the U.S. Food and Drug Administration approved the company's receptor tyrosine kinase inhibitor LENVIMA (lenvatinib) for the treatment of locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer (RAI-R DTC).

13 Feb 2015

Immune system exploits flu virus' dependence on host's machinery

Viruses are masters of outsourcing, entrusting their fundamental function - reproduction - to the host cells they infect. But it turns out this highly economical approach also creates vulnerability.

13 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

Doctor's Best adds three new sports nutrition powders to its science-based supplement portfolio

Doctor's Best has introduced three new sports nutrition powders – Creatine, Branched Chain Amino Acids (BCAA) and L-Arginine - into its science-based supplement portfolio.

13 Feb 2015

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Astute Medical, Inc., developer of the NephroCheck® Test, today previewed the upcoming AKI & CRRT 2015 conference to be held in San Diego from February 17 to February 20.

13 Feb 2015

Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

A new whitepaper from Malvern Panalytical provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.

From Malvern Panalytical 12 Feb 2015

Researchers identify RGS6 protein that controls both alcohol-seeking behavior and organ damage

What if there was a drug that could simultaneously curb a person's craving for alcohol while also protecting their heart and liver from alcohol's damaging effects?

12 Feb 2015

Researchers develop new method for preventing destructive activity of osteoclasts

Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of these very same osteoclast cells. Researchers from the CNRS, Inserm and the Université de Montpellier and Université Jean Monnet - Saint-étienne have developed a new approach for preventing the destructive activity of osteoclasts without affecting their viability.

12 Feb 2015

RAB3GAP complex plays important role in autophagy

Neurodegenerative disorders such as Alzheimer's disease are typically characterized by protein deposits in the brain. These are comprised of defective, insoluble proteins which no longer fulfill their function and which cells are unable to break down. The work group headed by Professor Christian Behl of the Institute of Pathobiochemistry of the University Medical Center of Johannes Gutenberg University Mainz has determined the RAB3GAP complex as a novel factor that influences the efficient degradation of proteins.

12 Feb 2015

SIB Swiss Institute of Bioinformatics designated as FAO Reference Centre for bioinformatics

The Food and Agriculture Organization of the United Nations (FAO) has appointed SIB Swiss Institute of Bioinformatics as the FAO Reference Centre for bioinformatics.

12 Feb 2015

Research provides new insights into rapid defence responses in human immune system

Researchers have uncovered a sieve-like structure in lymph nodes that regulates the transport of proteins and migration of white blood cells into lymph nodes.

12 Feb 2015

Rare and classic EGFR mutations have different impacts on NSCLC outcome

Certain rare epidermal growth factor receptor (EGFR) mutations are associated with tobacco smoking, worse prognosis and poor response to EGFR tyrosine kinase inhibitor (TKI) therapy compared to the more common "classical" EGFR mutations.

12 Feb 2015

Specific combinations of therapies kill cancer cells, reduce tumors

Controlling the time and sequence of cancer therapies may hold the key to unlocking better outcomes for patients with aggressive cancers, according to research published today.

12 Feb 2015

Understanding the pattern of cellular changes that lead to retinal ganglion cell death in glaucoma

Glaucoma, the second leading cause of blindness, usually stems from elevated eye pressure, which in turn damages and destroys specialized neurons in the eye known as retinal ganglion cells. To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease.

12 Feb 2015

Oral pathogen protects different tumor cells from being killed by immune cells

Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press February 18th in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells.

12 Feb 2015

Common protein may play strategic role in tumor growth

A common, yet previously undistinguished protein, which is elevated in many late-stage cancers, may play a strategic role in tumor growth through a non-conventional pathway, researchers at the Indiana University School of Medicine report in the Feb. 10 issue of the Proceedings of the National Academy of Sciences.

12 Feb 2015

Protein News and Research

Further Reading

Scientists find seven new genes that can cause X-linked intellectual disability

UT Southwestern researchers identify common signaling mechanism that controls immune system

A*STAR's GIS scientists develop new system that can predict treatment targets for cancer

New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC

Immune system exploits flu virus' dependence on host's machinery

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

Doctor's Best adds three new sports nutrition powders to its science-based supplement portfolio

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

Researchers identify RGS6 protein that controls both alcohol-seeking behavior and organ damage

Researchers develop new method for preventing destructive activity of osteoclasts

RAB3GAP complex plays important role in autophagy

SIB Swiss Institute of Bioinformatics designated as FAO Reference Centre for bioinformatics

Research provides new insights into rapid defence responses in human immune system

Rare and classic EGFR mutations have different impacts on NSCLC outcome

Specific combinations of therapies kill cancer cells, reduce tumors

Understanding the pattern of cellular changes that lead to retinal ganglion cell death in glaucoma

Oral pathogen protects different tumor cells from being killed by immune cells

Common protein may play strategic role in tumor growth

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