Chromatography News and Research

RSS

Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

The Emerging Field of Gene Therapy with Adeno-Associated Viruses

In this interview, Arnaud Delobel, the R&D and Innovation Director at Quality Assistance talks to NewsMed-LS about the emerging field of gene therapy with adeno-associated viruses (AAV).

From Waters | Wyatt Technology 18 Oct 2022

Do phthalates in face masks pose health hazards with increased usage during the COVID-19 pandemic?

In a new study, researchers investigated the presence of phthalic acid esters (PAEs) or phthalates in commercially available face masks to assess the health risks associated with the increased use of face masks during the coronavirus disease 2019 (COVID-19) pandemic.

17 Oct 2022

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

In a new study, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium cations (Ca2+) cations.

14 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes-;or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

In a new study, researchers synthesized and evaluated a silver and polyurethane nanocomposite surface coating material that exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Oct 2022

Consuming more omega-3s associated with better brain health and cognition in middle age

Eating cold-water fish and other sources of omega-3 fatty acids may preserve brain health and enhance cognition in middle age, new evidence indicates.

5 Oct 2022

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Researchers used various analytical characterization techniques to determine the biophysical attributes of the Imperial College London self-amplifying viral RNA vaccine (IMP-1) developed for SARS-CoV-2.

5 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

In a new study, researchers explored the crystalline structure of the monkeypox (MPX) virus (MPXV) and the complex of VP39, a 2′-O-RNA methyltransferase (MTase) and sinefungin, a pan-MTase inhibitor.

30 Sep 2022

Associations between potential endocrine-disrupting chemicals and female fertility in women attending fertility clinics

Researchers explored the correlation between female fertility and chemical mixtures.

30 Sep 2022

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

A new study demonstrated the efficacy of a newly engineered angiotensin-converting enzyme 2 (ACE2) based immunoadhesin against Omicron and other SARS-CoV-2 VOCs.

30 Sep 2022

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

A recent study explored the diet-exercise-gut microbiome dynamics in male bodybuilders.

30 Sep 2022

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein.

29 Sep 2022

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

New Jersey Institute of Technology researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic monoclonal antibodies being developed to treat a variety of diseases, from cancers to infectious diseases.

27 Sep 2022

Repligen expands process analytics portfolio with DRS Daylight Solutions agreement

Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, today announced it has entered into a strategic partnership and exclusive license agreement with DRS Daylight Solutions to expand the use of mid-infrared (mid-IR) technology in the bioprocessing market.

From Daylight Solutions Inc 22 Sep 2022

What are the effects of pesticides on neonates' health?

A new study explores the impact of pesticide exposure in neonates, reviewing current literature while evaluating the research methods used in this area.

20 Sep 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

Chromatography News and Research

Further Reading

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

The Emerging Field of Gene Therapy with Adeno-Associated Viruses

Do phthalates in face masks pose health hazards with increased usage during the COVID-19 pandemic?

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

Metabolite discovery offers a potential way to address metabolic conditions

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

Consuming more omega-3s associated with better brain health and cognition in middle age

Key biophysical attributes of a self-amplifying viral RNA vaccine developed for SARS-CoV-2

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

Structural analysis of monkeypox virus to guide the development of broad antiviral agents

Associations between potential endocrine-disrupting chemicals and female fertility in women attending fertility clinics

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

How are diet and exercise in bodybuilders associated with the gut microbiota and metabolites?

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

Repligen expands process analytics portfolio with DRS Daylight Solutions agreement

What are the effects of pesticides on neonates' health?

Molecular engineered low-cost highly effective RBD-based COVID vaccine

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest Life Science News