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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.
Researchers develop revolutionary approach to treat drug-resistant tumors

Researchers develop revolutionary approach to treat drug-resistant tumors

In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is resistant to the drugs being used. To treat drug-resistant tumors, doctors typically use multiple drugs simultaneously, a practice called combination therapy. [More]
Filipino women who move to Canada face breast cancer risk at younger age

Filipino women who move to Canada face breast cancer risk at younger age

Filipinos who move to Canada are diagnosed with breast cancer at a younger age than women from other parts of East Asia or Caucasians, new research has found. [More]
Study shows that even breast cancers with few androgen receptors benefit from anti-androgen therapy

Study shows that even breast cancers with few androgen receptors benefit from anti-androgen therapy

A University of Colorado Cancer Center study published today in the journal Molecular Cancer Therapeutics shows that only about 1 percent of triple-negative breast cancer cells in a tumor must be "androgen-receptor-positive" to show benefit from anti-androgen therapies. [More]
PCORI funds five patient-centered comparative effectiveness research studies

PCORI funds five patient-centered comparative effectiveness research studies

The Patient-Centered Outcomes Research Institute Board of Governors today approved awards totaling more than $64 million to fund five large patient-centered comparative effectiveness research (CER) studies that will answer critical clinical questions about care for cancer, back pain, and stroke. [More]
Study reveals how household net worth affects breast cancer care

Study reveals how household net worth affects breast cancer care

Household net worth is a major and overlooked factor in adherence to hormonal therapy among breast cancer patients and partially explains racial disparities in quality of care. The findings suggest that physicians, health insurers, and policy makers need to pay more attention to this economic variable to ensure that breast cancer patients receive this potentially life-saving treatment. [More]
Local woman with breast cancer endorses University of Leicester's plans to transform medical education

Local woman with breast cancer endorses University of Leicester's plans to transform medical education

A 41-year-old woman from Leicester has spoken of the transformative influence of well-trained doctors as she backed the University of Leicester's Centre for Medicine Appeal, encouraging everyone to play a part in the development of a new generation of healthcare and medical education for the region. [More]
Beneficial effects of statin treatment exaggerated, say researchers

Beneficial effects of statin treatment exaggerated, say researchers

Hailed as miracle drugs when they hit the market two decades ago, statins, the cholesterol-lowering drugs prescribed to prevent heart attacks, are not as effective nor as safe as we have been led to believe, say Dr. David M. Diamond, a professor of psychology, molecular pharmacology and physiology at the University of South Florida, and Dr. Uffe Ravnskov, an independent health researcher and an expert in cholesterol and cardiovascular disease. [More]
MD Anderson awarded more than $22 million in research grants from CPRIT

MD Anderson awarded more than $22 million in research grants from CPRIT

The University of Texas MD Anderson Cancer Center has received more than $22 million in research grants this week from the Cancer Prevention and Research Institute of Texas. Approximately half of the funds awarded for Individual Investigator Research Awards went to MD Anderson faculty as well as 40 percent of total IIRA awards that include those for children's and adolescent cancer and early detection and prevention. [More]
Palbociclib extends progression-free survival in advanced breast cancer patients

Palbociclib extends progression-free survival in advanced breast cancer patients

Palbociclib, an investigational oral medication that works by blocking molecules responsible for cancer cell growth, is well tolerated and extends progression-free survival (PFS) in newly diagnosed, advanced breast cancer patients, including those whose disease has stopped responding to traditional endocrine treatments. [More]
Betaretrovirus may infect patients with primary biliary cirrhosis

Betaretrovirus may infect patients with primary biliary cirrhosis

In a new study published in Alimentary Pharmacology & Therapeutics, researchers at the University of Alberta's Faculty of Medicine & Dentistry have shown that a betaretrovirus which resembles a mouse mammary tumor virus infects patients with the rare liver disease, primary biliary cirrhosis (PBC). [More]
Majority of women support idea of more frequent breast screening for individuals at higher risk of cancer

Majority of women support idea of more frequent breast screening for individuals at higher risk of cancer

Most women (85 per cent) would back the idea of more frequent breast screening if they are at higher genetic risk of developing breast cancer, according to research published today by The Breast. [More]

Targeting pericytes and ANG2 signaling may help treat certain breast cancers

Tumors require blood to emerge and spread. That is why scientists at The University of Texas MD Anderson Cancer Center believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach when combined with vascular growth factors responsible for cell death. [More]

LBBC to host metastatic breast cancer conference in April 2015

Philadelphia-based Living Beyond Breast Cancer, the national information and support organization, has opened registration for its ninth annual conference for women living with metastatic breast cancer. The event takes place Saturday, April 11 – Sunday April 12, 2015 at the Loews Philadelphia Hotel in Philadelphia, Pennsylvania. [More]
Facts about precision medicine

Facts about precision medicine

President Barack Obama is requesting an increase of $215 million in the 2016 federal budget to launch the Precision Medicine Initiative. This boost in funding for research will give genetic causes of cancer a national focus specifically around precision or "personalized" treatments for cancer in the future. [More]
President of MD Anderson selected as new fellow of AACR Academy

President of MD Anderson selected as new fellow of AACR Academy

Ron DePinho, M.D., president of The University of Texas MD Anderson Cancer Center, will be inducted as a new fellow of the American Association for Cancer Research Academy. He joins 10 other cancer leaders in the prestigious academy that recognizes people who have made significant contributions to cancer research. [More]
Women who understand risks associated with mammography screening make better screening choices

Women who understand risks associated with mammography screening make better screening choices

Women who understand the risk of over-detection and over-diagnosis associated with mammography screening have lower intentions to have a breast screening test, according to a new Lancet study. [More]
Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

Researchers identify molecule that plays key role in aggressive thyroid cancer, other cancers

Cancer researchers at Mayo Clinic's campus in Jacksonville, Florida, have identified a molecule they say is important to survival of anaplastic thyroid carcinoma (ATC) — a lethal tumor with no effective therapies. [More]
Researchers show how gene mutations cause common forms of cartilage tumors

Researchers show how gene mutations cause common forms of cartilage tumors

Duke Medicine researchers have shown how gene mutations may cause common forms of cartilage tumors. In a study published in the Feb. 16, 2015, issue of the Proceedings of the National Academy of Sciences, Duke researchers and their colleagues revealed that mutations in the isocitrate dehydrogenase (IDH) gene contribute to the formation of benign tumors in cartilage that can be a precursor to malignancies. [More]
ASU to host inaugural meeting for brand new scientific society in Tempe, Arizona

ASU to host inaugural meeting for brand new scientific society in Tempe, Arizona

Arizona State University will host a premiere opportunity to engage and mingle with luminaries in the burgeoning field of evolutionary medicine, a new interdisciplinary approach that is becoming an essential perspective in our view of disease, today's medical practice and the worldwide impact on public health as it hosts the Inaugural International Society for Evolution, Medicine & Public Health Meeting, March 19-21, 2015 in Tempe, Arizona. [More]
New study finds promising target for future therapies to treat breast and ovarian cancer patients

New study finds promising target for future therapies to treat breast and ovarian cancer patients

The Food and Drug Administration's recent approval of the drug olaparib for ovarian cancer patients with inherited mutations in the genes BRCA1 or BRCA2 came as welcome news to the thousands of women now eligible to receive it. A new study by Dana-Farber Cancer Institute scientists indicates that the pool of patients who can benefit from the drug is potentially much wider - and offers a ready means of identifying them. [More]