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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.
Study: Hedgehog cell signaling pathway may play role in breast cancer metastasis

Study: Hedgehog cell signaling pathway may play role in breast cancer metastasis

Molecules called long non-coding RNAs (lncRNAs) have been implicated in breast cancer but exactly why they cause metastasis and tumor growth has been little understood…until now. [More]
Genetic testing, risk factor assessment could improve prevention strategies for breast cancer

Genetic testing, risk factor assessment could improve prevention strategies for breast cancer

Scientists used mathematical models to show that analysing genetic data, alongside a range of other risk factors, could substantially improve the ability to flag up women at highest risk of developing breast cancer. [More]
University of Leeds researchers make new synthetic anti-cancer molecule

University of Leeds researchers make new synthetic anti-cancer molecule

Researchers at the University of Leeds have made a new synthetic anti-cancer molecule that targets two key mechanisms in the spread of malignant tumours through the body. [More]
Unique immunochemotherapy approach to treating pancreatic cancer

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease. [More]
Scientists discover ways to detect several toxic flame retardants in people's bodies

Scientists discover ways to detect several toxic flame retardants in people's bodies

A new peer-reviewed study found that people are contaminated with several toxic flame retardants rarely studied in the US, including one that has never before been detected in Americans called TCEP. Scientists tested urine samples of California residents for biomarkers of six chemicals, all of which were present. [More]
RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

Cancer researchers at Roswell Park Cancer Institute have identified two independent classes of novel candidate prognostic markers for ovarian cancer, advancing efforts to develop targeted therapies for the disease. The findings resulted from two separate studies published in the peer-reviewed journal PLoS ONE and based on data from The Cancer Genome Atlas (TCGA), the world's largest public database on gene expression in different tumor types. [More]
Internet based screening mammography training: an interview with Dr. Holzhauer

Internet based screening mammography training: an interview with Dr. Holzhauer

About half of Radiologists in the USA who participate in breast imaging are estimated to read less than 2,000 screening mammograms per year. This is a suboptimal number, given that only 3-5 cancers in average are seen among 1,000 screening mammograms. [More]
New vaccination approach can reduce tumor burden, suppress formation of lung metastases

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer. [More]
Eribulin drug has minor added benefit in one patient group, indication of lesser benefit in others

Eribulin drug has minor added benefit in one patient group, indication of lesser benefit in others

Eribulin (trade name: Halaven) is approved for women with locally advanced or metastatic breast cancer in whom the disease has progressed despite prior drug therapy. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether the drug offers an added benefit over the appropriate comparator therapy in these patient groups. [More]
Researchers obtain detailed picture of how Gas5 RNA interacts with steroid hormone receptors

Researchers obtain detailed picture of how Gas5 RNA interacts with steroid hormone receptors

It arises from what scientists previously described as "junk DNA" or "the dark matter of the genome," but this gene is definitely not junk. [More]
Olaparib shows promise for advanced cancers associated with BRCA1 and BRCA2 mutations

Olaparib shows promise for advanced cancers associated with BRCA1 and BRCA2 mutations

Olaparib, an experimental twice-daily oral cancer drug, produces an overall tumor response rate of 26 percent in several advanced cancers associated with BRCA1 and BRCA2 mutations, according to new research co-led by the Abramson Cancer Center of the University of Pennsylvania. [More]
Osteoporosis drugs may also benefit patients with tumours outside the skeleton

Osteoporosis drugs may also benefit patients with tumours outside the skeleton

Australian researchers have shown why calcium-binding drugs commonly used to treat people with osteoporosis, or with late-stage cancers that have spread to bone, may also benefit patients with tumours outside the skeleton, including breast cancer. [More]
Study sheds light on DCIS recurrence

Study sheds light on DCIS recurrence

Work by University of Manchester scientists has explored what allows some cases of Ductal Carcinoma in Situ (DCIS), a non-invasive form of breast cancer, to resist treatment and come back, as well as identifying a potential new target to improve the effectiveness of radiotherapy. [More]
Study: Hot flashes are not adequately managed in patients treated for breast cancer

Study: Hot flashes are not adequately managed in patients treated for breast cancer

Hot flushes are one of the most distressing conditions faced by women who have been treated for breast cancer, but they are not being adequately addressed by healthcare professionals and some women consider giving up their post cancer medication to try and stop them, a new study has shown. [More]
Incidence of colon and rectal cancer expected to increase by 2030 among young patients

Incidence of colon and rectal cancer expected to increase by 2030 among young patients

In the next 15 years, more than one in 10 colon cancers and nearly one in four rectal cancers will be diagnosed in patients younger than the traditional screening age, according to researchers at The University of Texas MD Anderson Cancer Center. [More]
New studies offer hope for breast cancer survivors struggling with cancer-related pain, swelling

New studies offer hope for breast cancer survivors struggling with cancer-related pain, swelling

Two new studies from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania offer hope for breast cancer survivors struggling with cancer-related pain and swelling, and point to ways to enhance muscular strength and body image. [More]
Study reveals impact of meditation, support groups at cellular level in breast cancer survivors

Study reveals impact of meditation, support groups at cellular level in breast cancer survivors

For the first time, researchers have shown that practising mindfulness meditation or being involved in a support group has a positive physical impact at the cellular level in breast cancer survivors. [More]
People with lactose intolerance at lower risk of suffering from certain cancers

People with lactose intolerance at lower risk of suffering from certain cancers

People with lactose intolerance are at lower risk of suffering from lung, breast and ovarian cancers, according to a new study by researchers at Lund University and Region Skåne in Sweden. [More]

AbbVie and Myriad Genetics expand Tumor BRACAnalysis CDx collaboration

Myriad Genetics, Inc. announced today that it has signed an expanded companion diagnostic agreement with AbbVie, Inc., a leading global biopharmaceutical company to use Tumor BRACAnalysis CDx™ as a companion diagnostic in support of AbbVie’s novel poly (ADP-ribose) polymerase or PARP inhibitor, veliparib. [More]
Seno Imagio breast imaging system and associated predictive model can help eliminate breast biopsies

Seno Imagio breast imaging system and associated predictive model can help eliminate breast biopsies

Seno Medical Instruments, Inc., the company pioneering the development of opto-acoustic technology as a new tool to improve the process of diagnosing breast cancer, announced that the use of the Seno Imagio breast imaging system and the associated predictive model appear to have the potential to significantly improve the physicians’ ability to accurately rule out breast cancer compared to traditional ultrasound alone. [More]