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Breast cancer is cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare. When breast cancer cells spread to other parts of the body, they are called metastases. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer. Breast cancer can begin in different parts of the breast, like the ducts or the lobes.
Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

Research brief describes enrollment of first patient with TRK fusion cancer in LOXO-101 Phase 1 trial

The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced the publication of a research brief in the online edition of the journal Cancer Discovery, describing the first patient with a tropomyosin receptor kinase (TRK) fusion cancer enrolled in the Phase 1 dose escalation trial of LOXO-101, the only selective TRK inhibitor in clinical development. [More]
Lidocaine benefits breast cancer survivors who experience pain during intercourse

Lidocaine benefits breast cancer survivors who experience pain during intercourse

Scientists at Oregon Health & Science University report that breast cancer survivors who experience pain during sexual intercourse, a common side effect of breast cancer treatment, may achieve comfort when liquid lidocaine is applied strategically to prevent pain. [More]
New special issue addresses hottest areas of research in cancer and metabolism

New special issue addresses hottest areas of research in cancer and metabolism

The latest Special Issue in ecancermedicalscience collects four original articles from experts in cancer and metabolism, addressing the hottest areas of research in this rapidly developing field. [More]

Study analyzes effect of shift work on prostate cancer

In a recent original article in Deutsches Ärzteblatt International (Dtsch Arztbl Int 112: 463-70), Gael P. Hammer et al. show that shift workers do not develop prostate cancer more frequently than their colleagues who work during the day. [More]
Case Western cancer researchers develop algorithm to detect DNA copy-number alterations in tumors

Case Western cancer researchers develop algorithm to detect DNA copy-number alterations in tumors

An algorithm dubbed ENVE could be the Google for genetic aberrations — and it comes from Case Western Reserve. [More]
Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards. [More]
Deep Genomics set to bring the power of deep learning technologies to genomics

Deep Genomics set to bring the power of deep learning technologies to genomics

Evolution has altered the human genome over hundreds of thousands of years -- and now humans can do it in a matter of months. [More]
Additional radiation to surrounding lymph nodes provides added benefit to breast cancer patients

Additional radiation to surrounding lymph nodes provides added benefit to breast cancer patients

A study has found no increase in overall survival but a reduction in breast cancer recurrence when additional radiation is given to the lymph nodes as well as the standard treatment of whole-breast irradiation after breast-conserving surgery. [More]
Genetic variation influences survival in patients with multiple myeloma

Genetic variation influences survival in patients with multiple myeloma

As part of a multi-institutional effort, researchers with Huntsman Cancer Institute at the University of Utah have found that multiple myeloma patients with a genetic variation in the gene FOPNL die on average 1-3 years sooner than patients without it. [More]
UCLA's Jonsson Comprehensive Cancer Center named among top 10 cancer centers in nation

UCLA's Jonsson Comprehensive Cancer Center named among top 10 cancer centers in nation

UCLA's Jonsson Comprehensive Cancer Center is ranked among the top 10 cancer centers in the nation, according to a U.S. News & World Report survey of board-certified physicians from across the country. The survey reviewed patient outcomes, the cancer center's reputation among physicians, mortality rates and other care-related factors. [More]
Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Tyrone Regional Health Network signs letter of intent to become member of Penn State Health

Tyrone Regional Health Network and Penn State Health have signed a letter of intent to enter into formal affiliation. With approval by organizational boards and state authorities, Tyrone Regional will become a member of Penn State Health. [More]
Breast cancer survivors in Appalachia not taking life-saving follow-up treatment, new study finds

Breast cancer survivors in Appalachia not taking life-saving follow-up treatment, new study finds

Nearly a third of breast cancer survivors in Appalachia are not taking the critical, potentially life-saving follow-up treatment - despite having insurance that would pay for it, a troubling new study has found. [More]

State healthcare regulations linked to late-stage cancer diagnoses

States' regulations of health insurance and practitioners significantly influence when patients receive colorectal or breast cancer diagnoses, especially among people younger than the Medicare-eligible age of 65, according to a new study by researchers at Georgia State University's School of Public Health and the University of North Carolina at Chapel Hill. [More]
Postmenopausal adiposity benefits with increasing aerobic exercise

Postmenopausal adiposity benefits with increasing aerobic exercise

An aerobic exercise regimen of 300 min/week versus 150 min/week significantly improves adiposity outcomes among postmenopausal women, shows research published in JAMA Oncology. [More]
NeoGenomics announces launch of new germline cancer predisposition testing services

NeoGenomics announces launch of new germline cancer predisposition testing services

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today the launch of a new line of germline cancer predisposition testing services. The new tests include comprehensive testing for BRCA1 and BRCA2 encompassing an analysis of all exons and adjacent intronic regions. [More]

UT scientists develop system to map out the odds of breast cancer recurrence in individual patients

Scientists of UT research institute MIRA have developed a system that maps out the odds of recurrence of breast cancer in individual patients. On the basis of information about the patient, the original tumour and the treatment used, they can accurately predict the odds of recurrence of breast cancer per year. [More]
Study shows that 14-3-3 sigma opposes, reverses tumor-promoting metabolic programs

Study shows that 14-3-3 sigma opposes, reverses tumor-promoting metabolic programs

Every parent knows the maxim "feed a cold, starve a fever." In cancer, however, exactly how to feed or starve a tumor has not been easy to determine. [More]
Two chemical compounds effectively inhibit growth of brain cancer cells and breast tumors

Two chemical compounds effectively inhibit growth of brain cancer cells and breast tumors

Researchers have discovered two chemical compounds that effectively stop the growth of brain cancer cells and breast tumors, opening the way for potential new drugs to be developed. [More]
Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Among women with a family history of breast cancer, those diagnosed with breast cancer gained weight at a greater rate compared with cancer-free women of the same age and menopausal status. [More]
Women with low levels of anti-stress hormone at increased risk of getting breast cancer

Women with low levels of anti-stress hormone at increased risk of getting breast cancer

A new study from Lund University in Sweden shows that women with low levels of an anti-stress hormone have an increased risk of getting breast cancer. The study is the first of its kind on humans and confirms previous similar observations from animal experiments. [More]
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