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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Treatment plans may include surgery, radiation and/or chemotherapy.
FDA and EC grant Orphan Drug Designation to Boehringer’s volasertib for acute myeloid leukemia

FDA and EC grant Orphan Drug Designation to Boehringer’s volasertib for acute myeloid leukemia

Boehringer Ingelheim Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) and European Commission (EC) have granted Orphan Drug Designation to volasertib for acute myeloid leukemia (AML). [More]
BRI scientists receive grant to study new approach to blocking metastatic breast cancer

BRI scientists receive grant to study new approach to blocking metastatic breast cancer

Benaroya Research Institute at Virginia Mason recently received a grant to research how blocking a particular molecule in metastatic breast cancer reduces both the growth of primary tumors and the number of lung metastases. [More]
Highly advanced imaging method helps to monitor rapid changes in glutathione redox potentials in live cells

Highly advanced imaging method helps to monitor rapid changes in glutathione redox potentials in live cells

In the April issue of Experimental Biology and Medicine a multidisciplinary research team led by Drs. Rex Gaskins and Paul Kenis in the Institute of Genomic Biology (IGB) on the campus of the University of Illinois Urbana-Champaign describe their recent work on subcellular redox homeostasis. [More]
Genmab/GSK receive FDA sBLA approval for Arzerra in combination with chlorambucil for treatment of CLL

Genmab/GSK receive FDA sBLA approval for Arzerra in combination with chlorambucil for treatment of CLL

GlaxoSmithKline plc and Genmab A/S announced today that the U.S. Food and Drug Administration (FDA) has approved a Supplemental Biologic License Application (sBLA) for the use of Arzerra® (ofatumumab), a CD20-directed cytolytic monoclonal antibody, in combination with chlorambucil for the treatment of previously untreated patients with chronic lymphocytic leukaemia (CLL) for whom fludarabine-based therapy is considered inappropriate. [More]
Study sheds light on tiny environments that stem cells occupy in animal bodies

Study sheds light on tiny environments that stem cells occupy in animal bodies

Johns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them. [More]
Benzodiazepines may contribute to respiratory problems in people with COPD

Benzodiazepines may contribute to respiratory problems in people with COPD

A group of drugs commonly prescribed for insomnia, anxiety and breathing issues "significantly increase the risk" that older people with chronic obstructive pulmonary disease, or COPD, need to visit a doctor or Emergency Department for respiratory reasons, new research has found. [More]
Research roundup: Colonscopy in the countryside; retiree health benefits; what should hip surgery cost?

Research roundup: Colonscopy in the countryside; retiree health benefits; what should hip surgery cost?

Rural residents who commonly seek treatment for advanced stages of colorectal cancer have been thought to lack access to cancer screening and adjuvant therapy. ... Several theories have been postulated to explain these findings, some of which include low socioeconomic status, lower educational attainment, lack of insurance coverage, underinsurance, and travel distance to health care facilities. [More]
Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells. [More]
Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

Stanford researchers identify normal cell type that gives rise to most invasive bladder cancers

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers at the Stanford University School of Medicine. [More]

Twenty years data analysis shows patients treated with HIPEC may have improved survival rates

Meaningful long-term survival is possible for selected patients suffering from advanced cancer of the abdomen when treated with cytoreductive surgery with Hyperthermic IntraPeritoneal Chemotherapy, or HIPEC, according to a first-of-its-size analysis by physicians at Wake Forest Baptist Medical Center. [More]
Researchers receive $3.7M NIH grant to develop anti-smoking program for HIV-infected smoker

Researchers receive $3.7M NIH grant to develop anti-smoking program for HIV-infected smoker

Montefiore Medical Center researchers have received a $3.7 million grant from the National Institute on Drug Abuse at the National Institutes of Health (NIH) to develop an anti-smoking program for HIV-infected smokers. [More]
Researchers devise new approach to treatment of Alzheimer's disease

Researchers devise new approach to treatment of Alzheimer's disease

A team of researchers from Columbia University Medical Center, Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating the potentially toxic byproduct amyloid-beta, which is thought to contribute to the development of Alzheimer's. [More]
Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions. [More]

At 8 million sign-ups, health law enrollment surpasses target

President Barack Obama hailed the latest tally of people who gained insurance as a result of the health law. News outlets also look inside this latest round of data to find out what information the administration is providing and what is still to come. [More]

Pfizer to highlight Blue Button initiative at DIA 2014 Annual Meeting in San Diego

Craig Lipset, head of clinical innovation at Pfizer Inc., will join advocates of patient data accessibility to highlight the Blue Button initiative at the DIA 2014 50th Annual Meeting in San Diego. [More]

Olympus' surgical products named finalists for ATA award

Olympus, a global technology leader in delivering innovative diagnostic and therapeutic solutions in Medical and Surgical procedures, among other core businesses, announced today that two of its surgical products have been named finalists for an American Technology Award (ATA) in the Health and Medical Technologies category: ENDOEYE FLEX 3D and THUNDERBEAT. [More]

WOTV 4's Maranda and Forest Hills Central students honored for contributing to community-based causes

The second annual Carol Van Andel Angel of Excellence dinner and award presentation took place on April 17, 2014. The event, hosted by Van Andel Institute (VAI), honored individuals who have made a significant contribution to the Institute through volunteer service, philanthropy, special event support, innovation or scientific support. [More]
Viewpoints: Obamacare still has more challenges; GOP needs to help make law work; census change is not Obama's decision

Viewpoints: Obamacare still has more challenges; GOP needs to help make law work; census change is not Obama's decision

The first open enrollment period under the Affordable Care Act ended this week with roughly 7.5 million people obtaining policies through the new state insurance exchanges, including more than 1.3 million at Covered California. [More]

Cyclenium Pharma signs drug discovery and development agreement with Southern Research Institute

Cyclenium Pharma Inc., an emerging pharmaceutical company specializing in the research and development of novel drug candidates based on proprietary macrocyclic chemistry, today announced the signing of a discovery and co-development agreement with Southern Research Institute, a not-for-profit 501(c)(3) scientific research organization founded in 1941. [More]

Research report on flow cytometry market

According to the new market research report "Flow Cytometry Market by Technology (Cell & Bead-based), Products & Services (Reagents, Instruments, Software, & Accessories), Application (Research & Clinical), End User (Commercial Organizations & Diagnostics Laboratories) - Global Forecasts to 2018", analyzes and studies the major market drivers, restraints, opportunities, and challenges in North America, Europe, Asia-Pacific, and Rest of the world (RoW). [More]