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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Treatment plans may include surgery, radiation and/or chemotherapy.
Can-Fite BioPharma's CF101Phase II/III psoriasis trial fails to meet primary endpoint

Can-Fite BioPharma's CF101Phase II/III psoriasis trial fails to meet primary endpoint

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today that its Phase II/III psoriasis trial for the Company's drug candidate CF101 did not achieve its primary endpoint. [More]
CASI receives CFDA approval for ENMD-2076 Phase 2 clinical trial in ovarian clear cell carcinoma

CASI receives CFDA approval for ENMD-2076 Phase 2 clinical trial in ovarian clear cell carcinoma

CASI Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the acquisition, development and commercialization of innovative therapeutics addressing cancer and other unmet medical needs for the global market with a commercial focus on China, announced today that the China Food and Drug Administration (CFDA) has approved the Company's application to conduct a Phase 2 global clinical trial in ovarian clear cell carcinoma (OCCC) patients for its proprietary drug candidate ENMD-2076. [More]
Maternal diet during pregnancy and lactation may influence weight gain in offspring

Maternal diet during pregnancy and lactation may influence weight gain in offspring

Maternal diet during pregnancy and lactation may prime offspring for weight gain and obesity later in life, according to Penn State College of Medicine researchers, who looked at rats whose mothers consumed a high-fat diet and found that the offspring's feeding controls and feelings of fullness did not function normally. [More]
RSV infection rate on the rise among young children

RSV infection rate on the rise among young children

Children with Respiratory Syncytial Virus (RSV), a common virus that infects the lungs and breathing passageways, has been on the rise across the nation for the last several years. Though it may only produce minor cold symptoms in adults, it can lead to serious illness in young children and those with compromised immune systems. [More]
Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

BioDelivery Sciences International, Inc. announced that the primary efficacy endpoint in the Phase 3 clinical study of Clonidine Topical Gel compared to placebo for the treatment of painful diabetic neuropathy did not meet statistical significance, although certain secondary endpoints showed statistically significant improvement over placebo. In addition, a strong safety profile for the product was observed. [More]
Researchers identify bio-markers that could help detect early stage colorectal cancer

Researchers identify bio-markers that could help detect early stage colorectal cancer

Colorectal cancer is the third most common form of cancer globally and the second most common cause of cancer deaths. The chance of a cure is high if the cancer is detected early enough, but early detection is not a given. Researchers from VIB and KU Leuven - together with various European oncology centers, including UZ Leuven - have identified bio-markers that can be incorporated in a new diagnostic test. [More]
Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

Study compares cost, benefits, complications of uterine-sparing treatments for fibroids

The relative cost, benefits, and complications of three minimally invasive techniques for reducing or eliminating symptomatic uterine fibroids are being compared in women who don't have cancer and want to preserve their uterus. [More]

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

The American Association for Cancer Research will honor Christopher R. Vakoc, MD, PhD, assistant professor at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, with the 35th annual AACR Outstanding Achievement in Cancer Research Award at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22. [More]
Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

Naldemedine meets primary and secondary endpoints in phase III study for OIC treatment

Naldemedine, an investigational peripherally acting mu-opioid receptor antagonist (PAMORA) under development by Shionogi & Co., Ltd., met its primary and secondary endpoints in a phase III study (COMPOSE I) for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain receiving opioid therapy. [More]
Benefits of physical activity outweigh harmful effects of air pollution

Benefits of physical activity outweigh harmful effects of air pollution

New research from the University of Copenhagen has found that the beneficial effects of exercise are more important for our health than the negative effects of air pollution, in relation to the risk of premature mortality. In other words, benefits of exercise outweigh the harmful effects of air pollution. [More]
Combination treatment improves outcomes in women with ovarian cancer

Combination treatment improves outcomes in women with ovarian cancer

Medical researchers are always looking for ways to prevent or cure cancer. Given the complexity of this disease, reaching these milestones has been difficult. [More]
Queen's University Belfast, NCI partners to provide 4 year PhD programme in Precision Cancer Medicine

Queen's University Belfast, NCI partners to provide 4 year PhD programme in Precision Cancer Medicine

Queen's University Belfast is leading a major new international initiative into modern cancer care medicine which was announced today in Washington D.C. [More]
Researchers evaluate decision aids for patient's choice of localised prostate cancer treatment

Researchers evaluate decision aids for patient's choice of localised prostate cancer treatment

Doctors strive to make treatment decisions together with their patients - but is the decision really shared? According to adjunct professor Kari Tikkinen, shared decision-making isn't easy, and clinicians need help. The international research group led by Tikkinen has studied the decision aids for treatment choice of localised prostate cancer [More]
MRI technique may help detect cancerous cells

MRI technique may help detect cancerous cells

Imaging tests like mammograms or CT scans can detect tumors, but figuring out whether a growth is or isn't cancer usually requires a biopsy to study cells directly. Now results of a Johns Hopkins study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells. [More]
Experimental nanoparticle therapy speeds healing of all sorts of wounds

Experimental nanoparticle therapy speeds healing of all sorts of wounds

An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology. [More]
Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Nanoparticles hold great promise for cancer diagnostics and therapies, but only to the extent that they can be selectively guided to tumors and cancer cells. [More]
Study quantifies long-term effects of nutrition deprivation at different stages of pregnancy

Study quantifies long-term effects of nutrition deprivation at different stages of pregnancy

A study by researchers at Columbia University's Mailman School of Public Health and colleagues in the Netherlands evaluated the relationship between nutritional conditions in very early life and adult health, and found that famine exposure during the first pregnancy trimester was associated with increases in mortality from a variety of causes other than cancer or cardiovascular disease. [More]
Discovery opens new drug development avenues for treating multiple diseases

Discovery opens new drug development avenues for treating multiple diseases

Researchers at the University of California, San Diego School of Medicine have discovered a control switch for the unfolded protein response (UPR), a cellular stress relief mechanism drawing major scientific interest because of its role in cancer, diabetes, inflammatory disorders and several neural degenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's disease. [More]
Bariatric surgery prior to joint replacement improves outcomes in obese patients

Bariatric surgery prior to joint replacement improves outcomes in obese patients

Obesity is not only a risk factor for developing knee and hip arthritis. It is also linked to less favorable outcomes after joint replacement surgery. [More]
Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria. [More]
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