Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Study investigates the production of a virosome-based COVID-19 vaccine candidate

In a new study, different signal peptides, baculovirus transfer vectors, cell lines, infection techniques, and formulation buffers were investigated with the purpose of building a scalable bioprocess to generate high-quality S protein for incorporation in a virosome-based COVID-19 vaccine candidate.

18 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

researchers discussed and identified the systemic functions and interactions of 52 active cell surface receptor tyrosine kinases, providing insights on RTK-RTK interactions and substrates, RTK-protein complexes, and signaling pathways.

13 Apr 2022

COVID-19 could change the levels of proteins related to male reproductive function

Many people who recover from COVID-19 experience long-term symptoms, such as brain fog or heart problems. Increasing evidence suggests that the virus can also impair fertility.

7 Apr 2022

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Researchers characterized SARS-CoV-2 spike (S) isolates extracted from the samples of two individuals infected with the virus in Peru (ΔN25) and Brazil (ΔN135) in January 2021.

6 Apr 2022

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.

6 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

A new study discovered immunoglobulins with powerful broad-acting neutralizing capacity against SARS-CoV-2 from SARS-CoV-2 convalescents.

5 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots contain isoflavonoids with high antioxidant and cytotoxic activity, scientists have discovered.

30 Mar 2022

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

A recent study presented topologically engineered fragment crystallizable-fusion proteins and antibodies as therapeutic options for diseases like human coronaviruses infections and cancers.

25 Mar 2022

IgG Fc glycosylation: A marker for severe COVID-19

Researchers suggest that low anti-spike IgG1 glycosylation, sialyation, and high bisection are markers of severe COVID-19.

24 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

$Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties$

Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties

A new study analyzed BoSG and its low molecular weight derivatives for their anticoagulant, anti-SARS-CoV-2, S-protein binding, and structural properties.

24 Mar 2022

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Researchers illustrated that vitamin D status and age influence antibody response following the initial dose of coronavirus disease 2019 vaccination.

21 Mar 2022

Acacetin shows potency against SARS-CoV-2 spike protein

Researchers use molecular docking to screen phytocompounds and evaluate their binding affinity with SARS-CoV-2.

15 Mar 2022

Merck and Waters to Collaborate on Extractables and Leachables Reference Library

Merck, a leading science and technology company, today announced that its Life Science business sector has entered into a collaboration with Waters Corporation to build and expand an Extractables and Leachables (E&L) Reference Library to include ion mobility measurements.

From Merck 11 Mar 2022

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

A new study used glycoprotein profiling technology platform that couples high-resolution LC-MS for glycoprotein analysis in regards to COVID-19.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Chromatography News and Research

Further Reading

Study investigates the production of a virosome-based COVID-19 vaccine candidate

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

COVID-19 could change the levels of proteins related to male reproductive function

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Gut bacterium may be an important factor in resistance to antihypertensive medications

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

Researchers use breast milk to identify new set of protein biomarkers for cancer

Soy molasses and kudzu roots may help fight against pediatric tumors

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

IgG Fc glycosylation: A marker for severe COVID-19

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

Study finds fractionation of sulfated galactan from red alga can isolate its anti-SARS-CoV-2 properties

Influence of vitamin D and age on first SARS-CoV-2 vaccine dose efficacy

Acacetin shows potency against SARS-CoV-2 spike protein

Merck and Waters to Collaborate on Extractables and Leachables Reference Library

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Current and future perspectives of mRNA technology

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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