Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Flow Eighteen38 receives €5 million EUR (c.$5.58 million USD) to expand production and biophysical capabilities

Flow Eighteen38, a protein sciences division created to facilitate and accelerate antibody characterization and protein purification projects, today announced a €5 million EUR (c.$5.58 million USD) investment into its protein production and biophysical characterization capabilities and services from its parent company, FairJourney Biologics S.A. (FJB), leaders in the discovery and optimization of antibodies.

From FairJourney Biologics S.A. 8 Mar 2022

Manipulating carotenoids can improve plant growth, stress tolerance and increase yield

Manipulating the content of carotenoids, such as ß-carotene, has been found to improve plant growth and increase yield and tolerance to abiotic stresses such as drought and salinity.

7 Mar 2022

Aldosterone levels undetectably low in hospitalized COVID-19 patients

A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.

6 Mar 2022

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers assess the ability of GC-IMS to differentiate between COVID-19 and other respiratory infections, as well as predict disease severity.

4 Mar 2022

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications.

3 Mar 2022

Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Artificially intelligent olfactory system may diagnose Parkinson’s disease at an early stage

A couple of years ago, a woman named Joy Milne made headlines when scientists discovered that she could "smell" Parkinson's disease (PD) on people with the neurodegenerative disorder.

23 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Researchers use an integrated approach to reveal constituents in a multi-herb Chinese medicine

Rooted in ancient knowledge and principles, traditional Chinese medicine (TCM) has been used to treat many diseases, sparking the interest of pharmaceutical researchers. TCM formulas are quite complex, requiring multiple herbs for their formulation.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Refeyn launches TwoMP Auto for automated protein characterisation at single-molecule level in solution

New mass photometer enables rapid, autonomous, and label-free mass characterisation of biomolecules at the single-molecule level

From Refeyn 14 Feb 2022

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Researchers studied the preclinical PK) and in vitro ADME properties of GS-441524, a potential oral drug for COVID-19 treatment.

10 Feb 2022

Process-scale Chromatography Bed Supports

Porvair Sciences high performance, precision manufactured Vyon® porous plastics are perfect support materials for chromatographic resins used in the isolation and purification steps of pharmaceutical drug and vaccine production.

From Porvair Sciences Limited 9 Feb 2022

Fast & efficient evaporator for chromatography solvents

Designed to provide dry down of samples in microplates and glass tubes up to 150 mm in length - the Ultravap® Mistral XT150 blowdown evaporator from Porvair Sciences offers a low maintenance, sample-safe alternative to using water bath-based evaporators.

From Porvair Sciences Limited 6 Feb 2022

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

In a new study, a team of researchers developed a hybrid vaccine for SARS-CoV-2 and influenza viruses using influenza virus-like particles (VLP).

4 Feb 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022