Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

Understanding Monoclonal Antibody Unfolding and Aggregation

A therapeutic monoclonal antibody and its Fab and Fc fragments were recently investigated using differential scanning fluorimetry, temperature-ramped dynamic light scattering, and turbidity measurements.

From Waters | Wyatt Technology 8 Nov 2019

DuPont to highlight innovative solutions for future pharma challenges at AAPS: PharmSci 360

DuPont Nutrition & Biosciences scientists have proven their expertise through decades of research and manufacturing excellence to create one of the industry’s broadest product portfolios.

From DuPont 8 Nov 2019

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

Rice scientists take a step toward simplifying drug manufacture

With a lot of hard work and a dash of salt, Rice University scientists have taken a step toward simplifying drug manufacture.

29 Oct 2019

Heuneburg Early Celts from all social classes may have used local ceramics to consume Mediterranean wine

Early Celts from the Heuneburg settlement may have enjoyed Mediterranean wine well before they began importing Mediterranean drinking vessels—and this special drink may have been available to all in the community, according to a study published October 23, 2019 in the open-access journal PLOS ONE by Maxime Rageot from Ludwig-Maximilians-Universität München and the University of Tübingen, and colleagues.

From PLOS ONE 18 Oct 2019

Researchers identify compounds that could help study the toxicological properties of fire ant venom

Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections and even kidney failure.

17 Oct 2019

Impress your boss with this course

In this webinar, Dr. Michael W. Dong, Pittcon Short Course Instructor, will review best practices, short cuts, and tricks-of-the-trade to help pharmaceutical and other scientists to become more successful in developing effective HPLC methods (potency and ICH-compliant stability-indicating assays) using method templates and universal generic gradient methods.

From Pittcon 14 Oct 2019

Researchers show how food estrogen migrates through the placenta

The human fetus is considered to be particularly sensitive to environmental contaminants. A team led by Benedikt Warth from the Faculty of Chemistry at the University of Vienna and Tina Bürki from the Swiss Materials Science and Technology Institute, Empa, has now been able to demonstrate for the first time how the widespread food estrogen zearalenone behaves in the womb.

10 Oct 2019

BIA Separations launches CORNERSTONE Exosome Process Development Solution

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its CORNERSTONE Exosome Process Development Solution, designed to help drug-developers overcome critical development bottlenecks in the preparation of exosomes for clinical use.

10 Oct 2019

Regional chromatography industry meeting in Berlin Zehlendorf was a great success

More than 50 users, technology visionaries and laboratory experts met on Monday, September 30, 2019 for a regional chromatography industry meeting in Berlin Zehlendorf to discuss opportunities and challenges of this analytical laboratory technology.

8 Oct 2019

Restek to present fundamentals of gas chromatography at Waters' GC-MS seminar

Chromatographers from Restek will be presenting at Waters’ upcoming seminar on October 23, 2019, in Wood Dale, IL. This educational opportunity is aimed at scientists looking to learn more about GC-MS capabilities in all areas, particularly in food and environmental applications.

From Restek Corporation 4 Oct 2019

Study shows how AF4-MALS-UV can separate and size large AAV aggregates

Postnova Analytics has published a new applications study that reports on how Asymmetric Flow Field Flow Fractionation (AF4) coupled with multi-angle light scattering (MALS) and Ultraviolet (UV) detectors can be used to quantify Adeno-Associated Virus (AAV) aggregation.

From Postnova Analytics 25 Sep 2019

New technique for police to quickly and safely test drug evidence

Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains illegal drugs without having to handle any suspicious contents directly.

17 Sep 2019

Atlas Antibodies presents QPrEST standards for absolute quantification of proteins using mass spectrometry

Atlas Antibodies AB, a leading supplier of advanced research reagents, announced today the introduction of pre-quantified QPrEST™ Protein Standards for absolute quantification of proteins in biological samples such as cell lysate and plasma using liquid chromatography (LC)–mass spectrometry (MS).

From Atlas Antibodies 16 Sep 2019

BIA Separations launches Cornerstone AAV Process Development Service to improve gene therapy production

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of CORNERSTONE AAV Process Development Service, a program of integrated process development services and novel technology designed to improve the robustness and yield of AAV-based gene therapy production, while improving the safety of therapeutic products.

12 Sep 2019

KNAUER joins industrial sustainability research project

Starting September 2019, KNAUER is now part of the EU funded IMPRESS research program, with the goal to advance the sustainable production of chemistry raw materials.

From KNAUER Wissenschaftliche Geräte GmbH 8 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

Using anion exchange chromatography and electrochemical detection for determination of carbohydrates

Carbohydrates are among the most widespread organic compounds in the living nature. As monosaccharides and di-saccharides, they primarily serve the direct supply of energy in the organism. In the form of oligomers or polymers, they are used more for storage of energy or information, or take over tasks as a structural element in cell walls, primarily of plants.

From KNAUER Wissenschaftliche Geräte GmbH 3 Sep 2019