Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Study pioneers phenotyping of human metabolome

The old excuse, "I am only overweight because of my genes," is suddenly gaining credibility as researchers uncover ever more evidence that the way our bodies digest and process nutrients in the food we eat is different for every person. The budding discipline of metabolomics strives to investigate these differences in a scientific manner.

12 Apr 2010

NMS Labs launches test to evaluate the efficacy of Milnacipran

NMS Labs launches another unique test suitable for the evaluation of toxicity vs. efficacy, the potential for physicians to establish therapeutic drug monitoring of individual patients, and the assessment of drug diversion of a new pain management drug therapy.

31 Mar 2010

ACS webinar on chemistry for food safety

Scheduled for Thursday, April 1, 2 - 3 p.m. Eastern Time, the free webinar will feature Walter Hammack with the Florida Department of Agriculture, as he discusses the various chromatographic tools, methods and regulations for food safety. His topic: "How Chemistry is Keeping Your Food Safe -Application of Ultra High Pressure Liquid Chromatography (UHPLC) in a Food Safety Laboratory."

24 Mar 2010

Agilent Technologies introduces new ion exchange and size exclusion columns for analysis of bio-molecules

Agilent Technologies Inc. today announced the availability of new ion exchange and size exclusion columns specifically designed for the analysis of bio-molecules including monoclonal antibodies, recombinant proteins, peptides, vaccine products and DNA/RNA. The columns provide robust, reproducible and high-resolution solutions for biopharmaceutical manufacturers to effectively monitor the safety, efficacy and stability of their products.

17 Mar 2010

Forensic Laboratories introduces first oral fluid test for Tapentadol

Forensic Laboratories, a Denver-based laboratory specializing in toxicology services for drug abuse, has unveiled the first oral fluid test for Tapentadol, a new federally approved drug prescribed by doctors for pain management. Previously, laboratories could only detect the drug through urine using liquid chromatography-mass spectrometry-mass spectrometry (LC/MS/MS) technology.

15 Mar 2010

Bruker to acquire certain product lines of Varian

Varian, Inc. announced today that Bruker Corporation and Agilent Technologies, Inc. have entered into a definitive asset purchase agreement pursuant to which Bruker will acquire certain product lines of Varian. As previously announced, Agilent committed to divest those product lines in connection with obtaining regulatory approval for Agilent's pending acquisition of Varian.

9 Mar 2010

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

AB SCIEX, a global leader in life science analytical technologies, today announced that it is collaborating with the University of Geneva’s Mass Spectrometry Centre to create new workflows and analytical strategies intended to significantly improve drug discovery and development.

4 Mar 2010

Repligen acquires BioFlash

Repligen Corporation announced today that it has acquired the assets of BioFlash Partners, LLC, (BioFlash) including a technology platform for the production of pre-packed, "plug and play" chromatography columns. This patented technology enables economical production of chromatography columns in a format that is ready for use in the production of a broad range of biopharmaceuticals including monoclonal antibodies, vaccines and recombinant proteins.

4 Mar 2010

Consumption of garlic reduces level of potential carcinogenic processes

Researchers have designed a urine test that can simultaneously measure the extent of a potential carcinogenic process and a marker of garlic consumption in humans.

2 Mar 2010

Agilent Technologies launches industry’s first transportable GC/MS system delivering laboratory-quality analysis

Agilent Technologies Inc. today introduced the 5975T Low Thermal Mass (LTM) Gas Chromatography/Mass Spectrometry Detector (GC/MSD), the industry’s first commercial transportable GC/MS system that delivers laboratory-quality analysis. Using proprietary LTM technology, Agilent has developed the 5975T LTM GC/MS to be smaller, more rugged and to consume less power than in-lab GC/MS instruments, yet capable of the same high-quality performance in the field.

2 Mar 2010

Agilent Technologies announces new lab informatics suite at Pittcon 2010

Agilent’s major new lab informatics suite, the OpenLAB portfolio, is designed to enable customers to easily capture, analyze and share scientific data throughout the lab and across the enterprise. OpenLAB is scalable, open architecture based on industry open standards.

2 Mar 2010

Supelco launches Ascentis Express Peptide ES-C18 HPLC columns

Supelco, a division of Sigma-Aldrich®, announced today the launch of Ascentis Express Peptide ES-C18, a high-speed, high-performance liquid chromatography (HPLC) column based on a new 160 angstrom Fused-Core™ particle design. This column design exhibits very high column efficiency, providing a stable, reversed phase packing with a pore structure and pore size that is optimized for reversed-phase HPLC separations of peptides and polypeptides.

26 Feb 2010

Aetna selects Millennium Laboratories as national pain management services provider

Millennium Laboratories, a leading provider of therapeutic drug monitoring and education to physicians and staff treating chronic pain patients, announced today a national agreement with Aetna, one of the nation’s leading diversified health care benefits companies that serves approximately 36.3 million people. Under the terms of the three-year ancillary services agreement which went into effect February 1, 2010, Millennium Laboratories’ will assist Aetna participating physicians nationwide with state-of-the-art therapeutic drug monitoring services and tools.

23 Feb 2010

Agilent Technologies wins breach of contract case against Advanced Materials Technology

Agilent Technologies Inc. today announced a favorable decision in its trade secrets and breach of contract case against Advanced Materials Technology, Inc. (AMT) and three of its employees in the Delaware Court of Chancery. Agilent filed the lawsuit in January 2008 to protect confidential and proprietary information relating to its high-performance liquid chromatography technology.

23 Feb 2010

Chiltern International and Charles River Laboratories to study radiolabelled drug products

Chiltern International Limited, a global contract research organization (CRO), announced its latest collaboration with Charles River Laboratories, Inc. As part of this collaboration, Chiltern Early Phase will partner with Charles River to conduct and support early phase radiolabelled studies.

22 Feb 2010

Health Canada approves Talecris Biotherapeutics' PROLASTIN-C for AAT deficiency

Talecris Biotherapeutics announced today that it has received approval from Health Canada for PROLASTIN®-C (Alpha1-Proteinase Inhibitor [Human]), a more purified and concentrated version of PROLASTIN® produced using advances in manufacturing technology. A similar approval for PROLASTIN-C was granted by the U.S. Food and Drug Administration on October 17, 2009.

17 Feb 2010

Waters launches new Viridis family of analytical and preparative SFC columns for compound purification

Waters Corporation introduces today Viridis™ SFC columns, a new family of analytical and preparative supercritical fluid chromatography (SFC) columns. Waters new Viridis SFC columns were developed to give laboratories using SFC a reliable source of high-quality columns for compound purification. Paired with Waters® TharSFC™ instrumentation laboratories now have a single source for both instrumentation and columns for their all-important purification work.

17 Feb 2010

BAC adds affinity resin for AAT purification to GE Healthcare’s range of custom designed media

BAC BV, the leading provider of antibody-based affinity purification technology, has extended its collaboration with GE Healthcare with the addition of a new bioprocess affinity chromatography ligand to GE Healthcare’s range of custom designed media. The latest addition to the range is an affinity resin for the purification of alpha-1 antitrypsin (AAT) from blood plasma, recombinant cell culture or transgenic sources. The new resin has been developed as part of GE Healthcare’s Custom Designed Media (CDM) programme and provides a new solution for AAT purification in the biopharmaceutical industry.

17 Feb 2010

AB SCIEX acquires liquid chromatography business of Eksigent Technologies

AB SCIEX, a global leader in life science analytical technologies, today announced that it has acquired the liquid chromatography business of Eksigent Technologies. This acquisition significantly strengthens AB SCIEX’s position in liquid chromatography, which is a key technology used frequently in a broad range of life science applications such as protein biomarker research, drug discovery and basic research.

16 Feb 2010

AB SCIEX technology solution implemented for anti-doping enforcement at the 2010 Winter Games

While millions of viewers around the world are watching breathtaking ski jumps, razor-sharp skating moves and other awe-inspiring athletic feats in Vancouver over the next few weeks, the official doping control laboratory of the 2010 Winter Games will be casting an equally intent eye on the athletes who are competing.

10 Feb 2010

Chromatography News and Research

Further Reading

Study pioneers phenotyping of human metabolome

NMS Labs launches test to evaluate the efficacy of Milnacipran

ACS webinar on chemistry for food safety

Agilent Technologies introduces new ion exchange and size exclusion columns for analysis of bio-molecules

Forensic Laboratories introduces first oral fluid test for Tapentadol

Bruker to acquire certain product lines of Varian

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

Repligen acquires BioFlash

Consumption of garlic reduces level of potential carcinogenic processes

Agilent Technologies launches industry’s first transportable GC/MS system delivering laboratory-quality analysis

Agilent Technologies announces new lab informatics suite at Pittcon 2010

Supelco launches Ascentis Express Peptide ES-C18 HPLC columns

Aetna selects Millennium Laboratories as national pain management services provider

Agilent Technologies wins breach of contract case against Advanced Materials Technology

Chiltern International and Charles River Laboratories to study radiolabelled drug products

Health Canada approves Talecris Biotherapeutics' PROLASTIN-C for AAT deficiency

Waters launches new Viridis family of analytical and preparative SFC columns for compound purification

BAC adds affinity resin for AAT purification to GE Healthcare’s range of custom designed media

AB SCIEX acquires liquid chromatography business of Eksigent Technologies

AB SCIEX technology solution implemented for anti-doping enforcement at the 2010 Winter Games

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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