Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers used a UHPLC and mass spectrometry-based Metabolon platform to identify and characterize circulating metabolites associated with depression.

1 Aug 2023

The essential role of the MPL36 protein in leptospirosis

The Leptospira membrane protein L36 (MPL36) is essential for its pathogenesis.

31 Jul 2023

Gyros Protein Technologies introduces PurePep EasyClean Auto Kit for automated parallel peptide purification

Gyros Protein Technologies AB, a leading provider of peptide synthesizers and reagents, and a pioneer in automated nanoliter-scale immunoassays, today announced the launch of its PurePep® EasyClean (PEC) Auto Kit for the automated parallel purification of peptides, accelerating downstream processes for research, development, and production of simple to complex peptide drugs and therapies.

From Gyros Protein Technologies AB 31 Jul 2023

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Researchers have developed scalable processes to convert β-pinene into 4-IPEC, a feedstock for synthesizing sustainable versions of paracetamol and ibuprofen.

19 Jul 2023

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

Researchers used a murine model to demonstrate that functional excision of murine PITPNA eventually led to hyperglycemia in mice.

19 Jul 2023

Study investigates the antioxidant activity of hemp leaves

Researchers explored the antioxidant potential and extraction efficiency of active compounds from hemp leaves using different solvents and mixtures.

11 Jul 2023

Unique plant extract mixture has potent anti-acne effects

Researchers evaluate the efficacy of FRO, a formula composed of fermented Rhus verniciflua Stokes and Orostachys japonicus, against acne pathogenesis via antimicrobial assessment and an in vitro analysis. FRO was found to contain phenolics such as gallic acid, fisetin, quercetin, and kaempferol and was determined to alleviate acne by inhibiting the growth of Cutibacterium acnes, inflammation, and excess sebum.

9 Jul 2023

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

Study uncovers three previously unknown membrane proteins in ovarian cancer

A study led by Nagoya University in Japan has identified three previously unknown membrane proteins in ovarian cancer.

7 Jul 2023

Novel workflow reveals untapped diversity in fatty acid isomers across all life forms

Researchers introduced a comprehensive workflow to discover unsaturated fatty acids (FA).

6 Jul 2023

Purecap method offers hope for purer and safer mRNA vaccines

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

5 Jul 2023

Berlin's senator for economic affairs, Franziska Giffey, and state secretary Michael Biel visit lab-tech company KNAUER

The management of KNAUER Wissenschaftliche Geräte GmbH, a well-known Berlin-based manufacturer of high-tech laboratory instruments.

From KNAUER Wissenschaftliche Geräte GmbH 26 Jun 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

$New facile strategy for proteome analysis using ultracentrifugation fractionation$

New facile strategy for proteome analysis using ultracentrifugation fractionation

Urine is one of the attractive sources for early and sensitive biomarker discovery since it can accumulate and reflect changes in the human body while being collected non-invasively.

16 Jun 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin-;generally prepared from porcine intestinal mucosa in China-;was threatened by African swine fever in 2018.

15 Jun 2023

Bergamot fiber shows promise in battling neurodegenerative disorders

Bergamot fiber (BF), a byproduct of citrus fruit processing, shows antioxidant properties and protects against neurotoxicity induced by amyloid beta protein (Aβ), suggesting potential benefits for Alzheimer's disease treatment and waste reduction.

13 Jun 2023

Bamboo's hidden treasures: unveiling the possible health-boosting powers of leaf and sheath extracts

Researchers explored the antioxidant and anti-inflammatory properties of bamboo leaves and sheaths.

13 Jun 2023

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Researchers evaluated the presence of coronavirus disease 2019 (COVID-19) drugs in river water.

8 Jun 2023

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Researchers evaluated the impact of dietary lysophosphatidylcholine (LPC), comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on retinal function in Alzheimer’s disease (AD)-associated retinopathy.