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Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.
Need for standardised guidelines to fight Alzheimer's disease

Need for standardised guidelines to fight Alzheimer's disease

Some 47 million people worldwide suffer from some form of dementia. Scientists are working feverishly to find a cure for the most common form, Alzheimer's. At the Congress of the European Academy of Neurology in Copenhagen, Prof Gunhild Waldemar issued an appeal for researchers to work together and draw up standardised guidelines for early identification and treatment of the disease. [More]
Researchers detect blood-brain barrier leakage in people with early AD using contrast-enhanced MRI

Researchers detect blood-brain barrier leakage in people with early AD using contrast-enhanced MRI

Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier (BBB) of people with early Alzheimer's disease (AD), according to a new study published online in the journal Radiology. The results suggest that increased BBB permeability may represent a key mechanism in the early stages of the disease. [More]
New CRISPR-EZ method makes genome editing much easier in mice

New CRISPR-EZ method makes genome editing much easier in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool. [More]
Imaging data shows brains may have capacity to reverse schizophrenia effects

Imaging data shows brains may have capacity to reverse schizophrenia effects

A team of scientists from across the globe have shown that the brains of patients with schizophrenia have the capacity to reorganize and fight the illness. This is the first time that imaging data has been used to show that our brains may have the ability to reverse the effects of schizophrenia. [More]
Study finds positive link between perceptual difficulty and insular cortex activity

Study finds positive link between perceptual difficulty and insular cortex activity

As the difficulty of making a decision based on sensory evidence increases, activity in the brain's insular cortex also increases, according to researchers at Georgia State University. [More]
Self-care can help nurses manage compassion fatigue

Self-care can help nurses manage compassion fatigue

The heart of healthcare is stressed. With longer shifts, staffing shortages and healthcare changes taxing our nurses, it's no surprise that up to 80 percent report suffering compassion fatigue at some point in their careers, according to recent studies. [More]
Research sheds new light on biological processes underlying neurodegeneration in AD

Research sheds new light on biological processes underlying neurodegeneration in AD

Progranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal theme shared across several common neurodegenerative diseases. [More]
PET imaging with PiB may help in early diagnosis of Alzheimer's disease

PET imaging with PiB may help in early diagnosis of Alzheimer's disease

The effort to find ways to detect and diagnose preclinical Alzheimer's disease (AD) has taken a big step forward with the use of positron emission tomography (PET), a "nuclear medicine" for imaging processes in the body, when PET is used with a special 'tracer' that binds to the amyloid plaques in the brain that are a characteristic cause of AD. [More]
Neuroscientist distinguishes different forms of dementia using MRI scans

Neuroscientist distinguishes different forms of dementia using MRI scans

Neuroscientist Anne Hafkemeijer is able to distinguish two different forms of dementia using advanced imaging techniques. This is the first step towards early recognition of dementia in patients on the basis of brain networks. PhD defence 26 May. [More]
Existing MCI screening tools result in more than 7% false-negative error rate, study finds

Existing MCI screening tools result in more than 7% false-negative error rate, study finds

Mild cognitive impairment (MCI) is a slight but noticeable and measurable decline in cognitive abilities, such as remembering names or a list of items. While changes may not be severe enough to disrupt daily life, a clinical diagnosis of MCI indicates an increased risk of eventually developing Alzheimer's disease or another type of dementia. [More]
Heart failure patients who receive influenza vaccine less likely to develop dementia

Heart failure patients who receive influenza vaccine less likely to develop dementia

Influenza vaccination is associated with a lower risk of dementia in patients with heart failure, according to a study in more than 20 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Ju-Chi Liu, director of the Division of Cardiovascular Medicine, Department of Medicine, Taipei Medical University - Shuang Ho Hospital, in New Taipei City, Taiwan. [More]
New Spherical Brain Mapping for dementia diagnosis

New Spherical Brain Mapping for dementia diagnosis

Diagnosis, treatment and care of dementia is one of the major concerns in neurology research and associated healthcare programs. Dementia affects older age groups with a greater frequency, and as our population ages, the burden of dementia on public health is rapidly increasing. [More]
Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. [More]
Coprophagia linked to neurodegenerative dementia

Coprophagia linked to neurodegenerative dementia

Coprophagia, eating one's feces, is common in animals but rarely seen in humans. Mayo Clinic researchers reviewed the cases of a dozen adult patients diagnosed with coprophagia over the past 20 years and found that the behavior is associated with a wide range of neuropsychiatric disorders, particularly neurodegenerative dementias. [More]
Moblie, wearable technology could hold key to reducing social isolation among dementia patients

Moblie, wearable technology could hold key to reducing social isolation among dementia patients

Moblie and wearable technology used to support independent living for people with dementia could hold the key to cutting social isolation. [More]
Experts find vast mental health treatment gap in China and India

Experts find vast mental health treatment gap in China and India

A third of the global burden of disease for mental, neurological and substance use disorders occurs in India and China – more than in all high-income countries combined – yet most people with mental disorders in these countries do not receive needed treatment. [More]
High blood pressure could increase vascular dementia risk

High blood pressure could increase vascular dementia risk

High blood pressure could significantly raise the risk of developing the second most common form of dementia, according to a new study from The George Institute for Global Health. [More]
New Research: High blood pressure raises risk of dementia

New Research: High blood pressure raises risk of dementia

High blood pressure could significantly raise the risk of developing the second most common form of dementia, according to a new study from The George Institute for Global Health. [More]
Memory test offers clue to pathological diagnosis in primary progressive aphasia

Memory test offers clue to pathological diagnosis in primary progressive aphasia

Patients with primary progressive aphasia show selective vulnerabilities in effortless learning and delayed retrieval of verbal information if their syndrome is related to Alzheimer's disease rather than frontotemporal lobar degeneration, research indicates. [More]
Physical fitness may offer protection from Alzheimer's disease, other dementias

Physical fitness may offer protection from Alzheimer's disease, other dementias

Recent research suggests that exercise might provide some measure of protection from Alzheimer's disease and other dementias. [More]
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