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Estrogens are a family of related molecules that stimulate the development and maintenance of female characteristics and sexual reproduction.

The natural estrogens produced by women are steroid molecules, which means that they are derived from a particular type of molecular skeleton containing four rings of carbon atoms, giving the shape shown here. The most prevalent forms of human estrogen are estradiol and estrone. Both are produced and secreted by the ovaries, although estrone is also made in the adrenal glands and other organs.
Long-term hormone treatment may negatively affect kidneys in postmenopausal women

Long-term hormone treatment may negatively affect kidneys in postmenopausal women

Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function. [More]
Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

It's somewhat of a little-known adverse effect of having breast cancer, but studies suggest that approximately 30% to 40% of women with breast cancer report persistent hot flashes. Nocturnal hot flashes are among the most problematic because they can contribute to poor sleep. [More]
Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Blocking key nutrient uptake may be effective way of treating triple negative breast cancer

Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines. [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Building on earlier clinical trials, UCLA researchers have confirmed that the "breakthrough" drug palbociclib when used in combination with the traditional hormonal therapy letrozole delays progression of advanced breast cancer significantly and without the harsh side effects seen in some women prescribed letrozole alone. [More]
Study finds positive link between later age at last pregnancy and cognitive function after menopause

Study finds positive link between later age at last pregnancy and cognitive function after menopause

A new study has found that women have better brainpower after menopause if they had their last baby after age 35, used hormonal contraceptives for more than 10 years or began their menstrual cycle before turning 13. [More]
Concerns about weight gain may affect contraception choices

Concerns about weight gain may affect contraception choices

Concerns about weight gain may be driving contraception choices, according to Penn State College of Medicine researchers. [More]
Allergan launches first and only oral contraceptive in softgel capsule for prevention of pregnancy

Allergan launches first and only oral contraceptive in softgel capsule for prevention of pregnancy

Allergan plc, a leading global pharmaceutical company, today announced the availability of TAYTULLA (norethindrone acetate and ethinyl estradiol capsules and ferrous fumarate capsules), 1mg/20mcg, the first and only oral contraceptive in a softgel capsule for the prevention of pregnancy [More]
Exposure to licorice compound disrupts steroid sex hormone production in ovary

Exposure to licorice compound disrupts steroid sex hormone production in ovary

A study of mouse reproductive tissues finds that exposure to isoliquiritigenin, a compound found in licorice, disrupts steroid sex hormone production in the ovary, researchers report. [More]
Study elucidates why women have higher risk of developing Alzheimer's disease than men

Study elucidates why women have higher risk of developing Alzheimer's disease than men

Women have a two-fold higher risk of developing Alzheimer's disease than men, yet strikingly little is known about how changes in brain function promote this difference -- and how early in midlife those changes can be detected. [More]
New study provides detailed timetable of sexual decline over menopause transition

New study provides detailed timetable of sexual decline over menopause transition

Although most medical professionals (and their patients) agree that sexual function declines with age, there remains debate about the contribution of menopause to sexual activity and functioning. [More]
NUS researchers identify molecular switch that makes breast cancer cells more aggressive

NUS researchers identify molecular switch that makes breast cancer cells more aggressive

A team of scientists from the National University of Singapore (NUS) has established novel insights into the relationship between breast cancer tumour intracellular redox environment and the cancer cells' ability to become invasive. [More]
Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

Researchers find link between estrogen levels in lung tissue and SMLA in postmenopausal women

Thanks to advances in medical imaging, the detection rate for synchronous multiple lung adenocarcinoma (SMLA) has been on the rise. Cases of SMLA in Japanese women have been on the rise despite having a national smoking rate of less than 10% in recent years. [More]
Low-dose estrogen therapy effective in alleviating menopause symptoms, study finds

Low-dose estrogen therapy effective in alleviating menopause symptoms, study finds

For early postmenopausal women concerned about the effectiveness of low-dose estrogen therapy for alleviating menopause symptoms such as hot flashes, night sweats, insomnia, and irritability, data from the Kronos Early Estrogen Prevention Study (KEEPS) was used to compare the efficacy of two forms of hormone therapy (HT) on menopause symptoms compared with placebo over 4 years. [More]
Painful sex in women after cancer needs to be addressed, UC Davis researcher suggests

Painful sex in women after cancer needs to be addressed, UC Davis researcher suggests

Painful sex in women after cancer treatment is relatively common, often treatable and needs to be addressed by medical providers, a UC Davis oncologist and researcher suggests. [More]
Small RNA molecules could contribute to serious pregnancy complication, study finds

Small RNA molecules could contribute to serious pregnancy complication, study finds

A family of small RNA molecules affects the development of cells that give rise to the placenta - an organ that transfers oxygen and nutrients from mother to fetus -- in ways that could contribute to a serious pregnancy complication, UT Southwestern Medical Center researchers report. [More]
Screening for prolactin receptor could help improve TNBC prognosis and treatment

Screening for prolactin receptor could help improve TNBC prognosis and treatment

A study conducted at the Research Institute of the McGill University Health Centre suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments [More]
New study examines how tumor genome testing helps improve breast cancer treatment

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy. [More]
Robot-assisted surgery at NYU Lutheran offers hope to women with endometrial cancer

Robot-assisted surgery at NYU Lutheran offers hope to women with endometrial cancer

Nandi Kumar Carpen, a 51-year-old wife, mother of two young girls, and a nurse at a major city hospital, noticed some "spotty" bleeding outside of her regular menstrual cycle. [More]
Gene variants linked to hot flashes in menopausal women

Gene variants linked to hot flashes in menopausal women

Most women experience hot flashes and night sweats either before or during menopause, but a significant minority don't have these symptoms. Could our genes be a factor in determining which women get hot flashes? [More]
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