Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

A new drug can help control an overactive thyroid, a major complication of advanced kidney disease, by playing a trick on the gland, a new study finds. The drug, cinacalet, is much more effective at keeping the parathyroid gland working normally than a placebo, according to the study. It may be a good alternative to standard therapy, researchers said.

7 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

Hormone associated with obesity also plays a key role in male fertility

Researchers in the University of Warwick’s Department of Biological Sciences have found that a hormone associated with obesity is actually also very active in the male genitals where it plays a key role in male fertility and may even influence the erection response in male sexual arousal.

6 Apr 2004

Launch of The Oxford Genetics Knowledge Park by Matt Ridley

The Oxford Genetics Knowledge Park is a partnership between Oxford University and the Oxford Radcliffe Hospitals NHS Trust, and is one of six such Parks nationally, funded by the Departments of Health and Trade and Industry. The aim of the Genetics Knowledge Parks (GKPs) is to translate advances in genetics research into clinical practice.

6 Apr 2004

Phase 3 study of drug teduglutide in patients with short bowel syndrome

Teduglutide is an analog of glucagon-like peptide 2 (GLP-2), a naturally occurring hormone that regulates the growth, proliferation and maintenance of cells lining the gastrointestinal tract. Teduglutide has been shown in animal studies and previous human clinical trials to increase the size and number of these cells, thereby increasing the absorptive surface area of the intestines.

6 Apr 2004

NeoRx Corporation acquires worldwide rights to platinum-based anti-cancer agent

NeoRx Corporation today announced that it has acquired from AnorMED Inc. the worldwide exclusive rights, excluding Japan, to develop, manufacture and commercialize AMD473, a platinum-based anti-cancer agent. AMD473 has been administered to more than 500 cancer patients in phase I and phase II clinical trials, demonstrating anti-cancer activity in a wide range of tumors and a manageable safety profile. NeoRx expects to initiate clinical studies of AMD473 in one or more cancer indications in the second half of this year.

5 Apr 2004

BRITONS risk dying prematurely from cancer due to ignorance

An NOP survey, released today by Cancer Research UK's Race for Life, reveals that only three per cent of those surveyed know that people who are overweight are more likely to develop cancer than people of normal weight, while 70 per cent are aware of the link with heart disease.

5 Apr 2004

Sheffield University pioneers osteoporosis research

A leading osteoporosis expert from Sheffield has been awarded the prestigious Society for Endocrinology Medal and the Kohn Foundation Award for his 25-year commitment to revolutionising the treatment and diagnosis of osteoporosis.

31 Mar 2004

Drug, Nembutal can suppress activity in colon cancer cells

A barbiturate once commonly used to treat anxiety may play a role in controlling the spread of colon cancer, say researchers from The University of Texas M. D. Anderson Cancer Center.

30 Mar 2004

Discovery of gender difference in cartilage cells may help spinal disc repair

When biologist Barbara Boyan discovered science’s first proof of biochemical differences between male and female cartilage cells, she began to question the approaches she and other researchers were taking to study cells. Was their thinking biologically relevant?

30 Mar 2004

Removal of thyroid glands may be unnecessary for most patients

An unpleasant postoperative procedure for thyroid cancer patients who have had their thyroid glands surgically removed may be unnecessary for most patients, according to Washington University researchers at Siteman Cancer Center and Barnes-Jewish Hospital in St. Louis.

30 Mar 2004

Trial of new drug that may halt progression of Type I Diabetes

The results of a long-term clinical trial on a new drug designed to inhibit the progression of type I diabetes was announced at the International Diabetes Society meeting in Cambridge, England, March 29. The findings of the 18-month long clinical trial confirm the drug's efficacy in improving a diabetic's ability to produce insulin.

30 Mar 2004

Researchers tap modified plant viruses to ward off cervical cancer-causing infections

New vaccinations to prevent infections that lead to cervical cancer and targeted therapeutics aimed at breast cancer were examples of research highlights presented by scientists today at the 95th Annual Meeting of the American Association for Cancer Research. Scientists described advances that feed into the drug development 'pipeline,' and show strong promise for controlling existing tumors or addressing the pathogen that causes tumors.

29 Mar 2004

Data on pre-clinical activity of satraplatin in prostate cancer to be released

Spectrum Pharmaceuticals, Inc has announced that new data on pre-clinical activity of satraplatin in prostate cancer cell lines are being presented at the 95th Annual Meeting of the American Association for Cancer Research (AACR) in Orlando, Florida.

29 Mar 2004

Oral medication for diabetes a step closer

University of Toronto researchers have shown that "designer molecules" can interact with the body's insulin receptor, a step toward the development of an oral medication for diabetes. U of T professors Lakshmi Kotra, Cecil Yip, Peter Ottensmeyer and Robert Batey have created the first small molecules using the three-dimensional structure of the insulin receptor. A receptor is the site on the surface of a cell to which molecules with specific tasks, such as hormones, attach themselves. Insulin's task is to initiate the utilization of sugar in the blood.

26 Mar 2004

Thyroid disorders are often misdiagnosed

Thyroid disorders are among the most common medical conditions. However, because their symptoms often appear gradually, the condition is often misdiagnosed, according to Dr. Nila Vora, a board-certified endocrinologist at the Loyola Primary Care Center in Darien.

25 Mar 2004

FDA Approves Pre-Filled Pre-Mixed Fertility Medication

The U.S. Food and Drug Administration (FDA) today announced approval of Follistim®-AQ TM cartridge (follitropin beta injection) in the United States. Follistim-AQ cartridge is the first follicle stimulating hormone (FSH) treatment available in a pre-filled, pre-mixed solution, eliminating the need for patients to mix one or more vials of medication.

24 Mar 2004

Stem cell research that could help diabetics

University of Florida adult stem cell experts have restored normal blood sugar levels in diabetic mice for three months by chemically coaxing bone marrow cells to produce insulin, a hormone normally made in the pancreas.

22 Mar 2004

Research suggests protein released from lungs could initiate labour

A protein released from the lungs of a developing mouse fetus initiates a cascade of chemical events leading to the mother's initiation of labor, researchers at UT Southwestern Medical Center at Dallas have found.

22 Mar 2004

Plasticiser Phthalates connected with rising infertility rates

Phthalates, largely used as plasticisers, have long been suspected in connection with rising infertility rates, particularly among men. These substances are quite common and are considered highly hazardous to human health because they disrupt the hormonal balance and impair reproduction and development. What has not been clear up to now is the amount of phthalates that enter the human body.

22 Mar 2004