Melanoma News and Research RSS Feed - Melanoma News and Research

Melanoma is a form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines.
Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, "Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient," that will be published online May 30 in The Journal of Experimental Medicine. [More]
Researchers develop new drugs for melanoma

Researchers develop new drugs for melanoma

Finding new, more effective and personalised treatments for cancer is the challenge of many researchers. A challenge that has been successfully met by a team from Inserm led by St├ęphane Rocchi, which has just synthesised and developed new drugs for melanoma. [More]
TSRI study shows how specific gene mutation promotes growth of aggressive tumors

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors. [More]
Adolescents and young adults have lower cancer survival rates compared to children

Adolescents and young adults have lower cancer survival rates compared to children

More young people of all ages are surviving cancer than ever before, but new research published today in The Lancet Oncology journal shows that adolescents and young adults have a lower chance of surviving eight relatively common types of cancer than children, according to the latest data from a long-running study of cancer survival across Europe. [More]
Novel photonics device that listens to light can accurately detect skin cancer

Novel photonics device that listens to light can accurately detect skin cancer

Scientists are developing a new photonics device that listens to light and could be capable of detecting skin cancer and other diseases more accurately than ever before, eliminating the need for unnecessary and invasive biopsies. [More]
Advanced cancer patients lack palliative, hospice care

Advanced cancer patients lack palliative, hospice care

Medical societies, including the American Society of Clinical Oncology, recommend that patients with advanced cancer receive palliative care soon after diagnosis and receive hospice care for at least the last three days of their life. Yet major gaps persist between these recommendations and real-life practice, a new study shows. [More]
SBP scientists discover new regulator of immune responses

SBP scientists discover new regulator of immune responses

Research led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a new regulator of immune responses. The study, published recently in Immunity, sheds new light on why T cells fail to clear chronic infections and eliminate tumors. [More]
Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells. [More]
Researchers find ways to switch on Natural Killer cells to combat cancer

Researchers find ways to switch on Natural Killer cells to combat cancer

Our bodies are constantly and successfully fighting off the development of cells that lead to tumours - but when there is disruption to this process cancer is free to develop. [More]
Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial. [More]
Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount. [More]
Malicious form of ATF2 protein drives formation of melanoma

Malicious form of ATF2 protein drives formation of melanoma

An international collaborative study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a malicious form of a protein that drives the formation of melanoma. [More]
Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Study assesses utility of tumor cfDNA as predictor of therapeutic response to immunotherapy

Chronix Biomedical, Inc., a developer of blood-based molecular diagnostics, today announces positive data from a blinded proof of concept clinical study, assessing the utility of tumor cell-free DNA as a predictor of therapeutic response to immunotherapy after the first cycle of treatment in eight different types of cancer. [More]
Radiation-immunotherapy combination can help treat melanoma

Radiation-immunotherapy combination can help treat melanoma

Combining radiation treatments with a new generation of immunotherapies is showing promise as a one-two-punch against melanoma, Loyola Medicine researchers report in a review article. [More]
Borrowed immune system may help combat cancer

Borrowed immune system may help combat cancer

A new step in cancer immunotherapy: researchers from the University of Oslo/Oslo University Hospital and the Netherlands Cancer Institute show that even if one's own immune cells cannot recognize and fight their tumors, someone else's immune cells might. [More]
Research on immune system sets stage for novel approach to cancer immunotherapy

Research on immune system sets stage for novel approach to cancer immunotherapy

Basic research into the dual nature of certain immune system cells has set the stage for a new approach to cancer immunotherapy that avoids some of the shortcomings associated with other methods, scientists at Dana-Farber Cancer Institute report in a new study in the Proceedings of the National Academy of Sciences. [More]
Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models. [More]
Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines. [More]
UV clothing can give better sunblock

UV clothing can give better sunblock

Just as most people know there is no such thing as safe smoking, there is also no such thing as safe sunbathing or tanning. Exposure to UVA and UVB rays can cause more than just a sunburn or tan - it can lead to everything from wrinkles to skin cancer. [More]
Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

Bim protein may hold clue for immunotherapy response in metastatic melanoma patients

A protein called Bim may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma, according to the results of a study by Mayo Clinic researchers led by senior author Haidong Dong, M.D., Ph.D., and published online in the May 5 edition of JCI Insight. [More]
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